MB:- 603 CLINICAL DIAGNOSTIC MICROBIOLOGY
UNIT:-4 EPIDEMIOLOGY AND MICROBIAL AGENTS OF DISEASE
4.2 CANDIDA ALBICANS
Rajani vishva j
Roll no:- 33

 CANDIDA ALBICANS
A. Introduction
B. Pathogenesis and clinical features
C. Laboratory Diagnosis
D. Treatment
E. Prevention

 A INTRODUCTION
 Candida Albicans also known as CANDIDIASIS.
 It is yeast like fungi.
 It is unicellular
 Dimorphic Yeast
 Reproduction :- Budding and Fission.
 Microscopic Appearance:- Spherical, oval form (in tissue)

 Kingdom :- Fungi
 Family :- Saccharomycetaceae
 Species :- C. Albicuns
 Distribution : Candida species are normally found on skin
surface and mucos.
 Candida sp. Mostly grow in warm and moise area.

 CANDIDOSIS ( CANDIDIASIS / MONILIASIS)
 Candidosis refers to an infection of skin mucosa and rarly of the
internal organs.
 A yeast infection of the vagina and tissues.
 Very rarely, yeast infections may become invasive, spreading to
other parts of the body.

 SYMPTONS:
 White Patches
 Cause intense itching
 Redness
 Growing skin rash

 B :- PATHOGENESIS AND CLINICAL FEATURES
 Mucosal Lesion:-
 Common lesions are varginities:- acidic discharge ( frequently
in pregenancy)
 Oral thrush:- creamy whitch patches apper on the tounge or
buccal mucosa.

ORAL CANDIDIASIS

 Oesophagel Cndidiasis :-
 It is also know as an THRUSH
 Tube that connected to the throat to the stomach.
 Considered an AIDS – defining illness.

Oesophage Candidiasis

 C:- LABORATORY DIAGNOSIS :-
 Microscopy.
 Wet films/ gram staines smears from lesions show budding
gram positive cells.
 Candida can colonise normal skin or mucosa as well .

 Respiratory Casndidiasis
 Blood culture test

 D :- TREATMENT
 Amphoteecian B
 5- Flurocytosine
 Imidazoles ( micronozole, Ketoconazole)
 Triazoles
 Some clinical isolates of C albican are resistant to fluconazole
and amphotericin.

 E :- PREVENTION OF INFECTION
1.Maintaining good oral and physical hygiene.
2.Eating a well-balanced diet.
3.Managing your stress.
4.Managing your blood sugar levels if you have
diabetes.