Is it possible that "nodding disease" in Uganda is coming from pigs infected with a new chronic or subacute strain of African Swine Fever Virus? African Swine Fever has been a serious problem in Uganda. It has become endemic in Uganda. Scientists often quickly dismiss the notion of a human epidemic of African Swine Fever Virus because they think African Swine Fever Virus does not infect people. But that may not be the case. Sick or ASFV-infected pigs in places like Gulu, Anaka, Arua, Kitgum, Masindi, and Pader may be the source of a "nodding disease" zoonotic virus. Even if the pigs are not overtly sick, they could be carriers of a strain of this very insidious virus. African Swine Fever Virus infects many parts of the pig's body, including the brain. It causes serious neurological damage. It is also interesting that in some epidemics of African Swine Fever, it is mainly the young piglets that are affected which would be a strong parallel to "nodding disease." The ASFV-infected piglets suffer from ataxia, wasting, stunted growth, blindness, increased salivation, and opportunistic infections, just like the children with Nodding Disease.
America's Centers for Disease Control has been investigating Nodding Disease for almost three years without figuring out what the cause is. They have yet to test the Ugandan children with Nodding Disease for African Swine Fever Virus. That raises serious questions about the CDC's credibility and competence.
According to a patent,"Polypeptides from African Swine Fever virus as vaccines for preventive and therapeutic use," (http://www.google.com/patents/US20080131449) filed by Matthias Rath, "African Swine Fever is an endemic disease in sub-Saharan Africa and many other parts of the developing world. It is caused by the African Swine Fever virus that primarily replicates in macrophages and monocytes leading to the impairment of the structure and function of the immune system of the infected organisms. Until now the African Swine epidemic continues to spread despite all efforts to contain it. Thus, there is an objective need for effective, safe and affordable preventive and therapeutic approaches, in particular for effective vaccines, to control and eventually eradicate this disease. Since the characteristic feature of the African Swine Fever virus is to impair the immune system and to cause immune deficiencies in its hosts the development of vaccines and other therapeutic approaches against the African Swine Fever virus has implications for other immune deficiencies or diseases. Since antibodies for the African Swine Fever virus have been detected in humans, the possibility of human infection with the African Swine Fever virus exists and may thus far have escaped any systematic screening. Thus, any preventive and therapeutic approach to African Swine Fever can have far-reaching implications to control immune deficiency conditions in humans. "