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Document #:600-03-00021 Rev AA
Salient Imaging
pioneer in the development of medical imaging software algorithms
 Private U.S. Corporation
 Patented Te...
Salient Imaging’s technology is based on proven pattern recognition principles
Pattern Recognition is a well established a...
Salient Imaging’s technology is based on proven pattern recognition principles
Pattern Recognition is a well established a...
Visualize:Vascular
Current technology The crucial diagnostic The Salient Image
shows the outside information is inside of ...
Technology
Works on a transverse cine clip of the artery
Technology
Finds the lumen on each frame
Visualize:Vascular Technology
Finds the lumen on each frame
Reconstructs 3D rendering of the lumen
Visualize:Vascular Technology
Clinical Value
Comparison of CDE to Visualize:Vascular to MRA
• 100 consecutive cases
• Any case where Visualize disagreed...
The images to the left are from a study comparing the
results of 2D Ultrasound to 3D Visualize:Vascular over
the same sect...
Ultrasound
Some plaque
The complete outline and
extent of the plaque
Visualize:Vascular
Magnetic Resonance Angiography (MR...
Ultrasound
Velocities show 80-89%
Visualize:Vascular
▪No significant concern, 52%
MRA
No significant concern, no break
...
Ultrasound
Velocities show 70-79%
Visualize:Vasclar
Over 80%
Clinical Significance –Turbulence
Ultrasound
Velocities show 70-79%
Visualize:Vascular
Over 80%
Clinical Significance –Turbulence
Ultrasound
Velocities show 70-79%
Visualize:Vascular
Over 80%
Clinical Significance –Turbulence
Ultrasound
Velocities show 50-69%
Visualize:Vascular
Significant concern, 92%
CTA
Significant concern, 90%
CTA confirm...
The procedure should be performed on patients who demonstrate medical
necessity observed during the primary exam:
Noted Pr...
Document #:600-02-00003 Rev AA
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Visualize vascular  (slides) Slide 1 Visualize vascular  (slides) Slide 2 Visualize vascular  (slides) Slide 3 Visualize vascular  (slides) Slide 4 Visualize vascular  (slides) Slide 5 Visualize vascular  (slides) Slide 6 Visualize vascular  (slides) Slide 7 Visualize vascular  (slides) Slide 8 Visualize vascular  (slides) Slide 9 Visualize vascular  (slides) Slide 10 Visualize vascular  (slides) Slide 11 Visualize vascular  (slides) Slide 12 Visualize vascular  (slides) Slide 13 Visualize vascular  (slides) Slide 14 Visualize vascular  (slides) Slide 15 Visualize vascular  (slides) Slide 16 Visualize vascular  (slides) Slide 17 Visualize vascular  (slides) Slide 18 Visualize vascular  (slides) Slide 19
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Visualize vascular (slides)

Visualize:Vascular generates focused 3-D rendering from 2-D standard ultrasound images and effectively tracks the true lumen in arterial pathways. Visualize focuses on the lumen and residual lumen by essentially removing the other image content revealing a 3-D rendering of the active area through which the blood can flow. Visualize provides direct luminal measurements to calculate luminal reduction directly from ultrasound imaging.

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Visualize vascular (slides)

  1. 1. Document #:600-03-00021 Rev AA
  2. 2. Salient Imaging pioneer in the development of medical imaging software algorithms  Private U.S. Corporation  Patented Technology in Imaging Algorithms  U.S. FDA certified product: Visualize:Vascular™  1st 3D rendering from 2D ultrasound focusing on the true lumen Company
  3. 3. Salient Imaging’s technology is based on proven pattern recognition principles Pattern Recognition is a well established and widely used method of identifying and classifying complex data sets  Mammography  Lung  Colon  Liver  Brain Tumor Salient Imaging applies these proven practices to medical imaging to specifically focus on ultrasound Technology
  4. 4. Salient Imaging’s technology is based on proven pattern recognition principles Pattern Recognition is a well established and widely used method of identifying and classifying complex data sets  Mammography  Lung  Colon  Liver  Brain Tumor Salient Imaging applies these proven practices to medical imaging to specifically focus on ultrasound Technology
  5. 5. Visualize:Vascular Current technology The crucial diagnostic The Salient Image shows the outside information is inside of the residual lumen of the carotid artery the carotid artery in the ICA  Find the overriding pattern  Identify the anomaly  Create focused 3D rendering  Automatically measure and calculate luminal reduction / Stenosis  Provide clinicians with focus on the salient diagnostic detail
  6. 6. Technology Works on a transverse cine clip of the artery
  7. 7. Technology Finds the lumen on each frame
  8. 8. Visualize:Vascular Technology Finds the lumen on each frame Reconstructs 3D rendering of the lumen
  9. 9. Visualize:Vascular Technology
  10. 10. Clinical Value Comparison of CDE to Visualize:Vascular to MRA • 100 consecutive cases • Any case where Visualize disagreed with Doppler or >70% on either also had MRA Key Findings: Correlation between CDE to Visualize 75% Correlation between MRA and Visualize 99% Gurell, et. al. ACR/SRU 2012 Key Findings: Correlation between CDE to Visualize 75% Correlation between MRA and Visualize 99%
  11. 11. The images to the left are from a study comparing the results of 2D Ultrasound to 3D Visualize:Vascular over the same section of the carotid artery Top Image: Ultrasound color flow can mis-lead  Measured Moderate Stenosis of 50 to 69%  Measurement is made in color block at left which is beyond the Stenosis (black)  Ultrasound data indicates patient call back in 1 yr Bottom Image: Visualize:Vascular is more accurate  Measured Severe Stenosis (85%)  Visualize data indicates immediate surgery Visualize:Vascular is Correct  Pathology confirmed that Visualize:Vascular is correct. Patient has severe amount of plaque in vessel. Clinical Significance – Shadowing
  12. 12. Ultrasound Some plaque The complete outline and extent of the plaque Visualize:Vascular Magnetic Resonance Angiography (MRA) Break Clinical Significance – Poor Fidelity The images to the right are from a case study comparing the results of 2D Ultrasound and MRA technologies to Visualize:Vascular the over the same section of artery Top Image: Ultrasound shows the outer arterial walls with limited detail of the lumen pathway, no significant plaque Middle Image: Visualize:Vascular Significant vulnerable plaque provides the most clinical detail about the region of interest Bottom Image: MRA shows that there is an occlusion by the break, but does not give specific detail Pathology confirmed results from Visualize
  13. 13. Ultrasound Velocities show 80-89% Visualize:Vascular ▪No significant concern, 52% MRA No significant concern, no break MRA confirmed results from Visualize Clinical Significance – Tortuosity
  14. 14. Ultrasound Velocities show 70-79% Visualize:Vasclar Over 80% Clinical Significance –Turbulence
  15. 15. Ultrasound Velocities show 70-79% Visualize:Vascular Over 80% Clinical Significance –Turbulence
  16. 16. Ultrasound Velocities show 70-79% Visualize:Vascular Over 80% Clinical Significance –Turbulence
  17. 17. Ultrasound Velocities show 50-69% Visualize:Vascular Significant concern, 92% CTA Significant concern, 90% CTA confirmed results from Visualize Clinical Significance – Artifact?
  18. 18. The procedure should be performed on patients who demonstrate medical necessity observed during the primary exam: Noted Presence of Plaque Noted Presence of Tortuosity Noted Presence of Artifacts: Shadowing, Speckling, Fidelity Concerns Noted Presence of Turbulent Flow Conditions Follow-up to Surgery or Interventional Procedure Medical Necessity
  19. 19. Document #:600-02-00003 Rev AA

Visualize:Vascular generates focused 3-D rendering from 2-D standard ultrasound images and effectively tracks the true lumen in arterial pathways. Visualize focuses on the lumen and residual lumen by essentially removing the other image content revealing a 3-D rendering of the active area through which the blood can flow. Visualize provides direct luminal measurements to calculate luminal reduction directly from ultrasound imaging.

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