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Critical appraisal: Checklists
Dr. S. A. Rizwan, M.D.
Public Health Specialist
SBCM, Joint Program – Riyadh
Ministry of Health, Kingdom of Saudi Arabia
Learning objectives
Critical appraisal of health literature SBCM, Joint Program – Riyadh
• Describe the role of checklists in critically
appraise of a research article
• Describe the difference between checklists and
critical appraisal
• Describe advantages and limitations of checklist
2
Introduction
Critical appraisal of health literature SBCM, Joint Program – Riyadh
• Reporting guidelines checklist
• An instrument which ensures that all studies
of a particular design report all the essential
items
• Enables the reader to make complete sense
of the study
• Standardises the reporting of findings
• Enables a valid critical appraisal to be done
3
Introduction
Critical appraisal of health literature SBCM, Joint Program – Riyadh
• Critical appraisal
• It is a process which enables the reader to
determine whether what has been reported
is right or wrong, truthful or not.
4
Section 1: RCTs
Critical appraisal of health literature SBCM, Joint Program – Riyadh
Reporting guidelines
Critical appraisal of health literature SBCM, Joint Program – Riyadh
• Whether details are mentioned or not?
(intentional or unintentional?)
6
Critical appraisal: Cochrane tool
Critical appraisal of health literature SBCM, Joint Program – Riyadh 7
Example of Cochrane ROB tool
Critical appraisal of health literature SBCM, Joint Program – Riyadh 8
Critical appraisal: Non-Cochrane tool
Critical appraisal of health literature SBCM, Joint Program – Riyadh 9
Section 2:
Case control,
cohort, cross-
sectional studies
Critical appraisal of health literature SBCM, Joint Program – Riyadh
Reporting guidelines
Critical appraisal of health literature SBCM, Joint Program – Riyadh
• Whether details are mentioned or not?
(intentional or unintentional?)
11
Critical appraisal tools
Critical appraisal of health literature SBCM, Joint Program – Riyadh 12
A Cochrane Risk Of Bias Assessment Tool: for Non-
Randomized Studies of Interventions (ACROBAT-NRSI)
ACROBAT-NRSI (7 domains)
Critical appraisal of health literature SBCM, Joint Program – Riyadh 13
Example of ACROBAT NRSI tool
Critical appraisal of health literature SBCM, Joint Program – Riyadh 14
Example of ACROBAT NRSI tool
Critical appraisal of health literature SBCM, Joint Program – Riyadh 15
Section 3:
Case series, case
reports
Critical appraisal of health literature SBCM, Joint Program – Riyadh
Reporting guidelines
Critical appraisal of health literature SBCM, Joint Program – Riyadh 17
Critical appraisal tools
Critical appraisal of health literature SBCM, Joint Program – Riyadh 18
For case reports
For case series
CEBM tool for case report
Critical appraisal of health literature SBCM, Joint Program – Riyadh 19
Carey et al tool for case series
Critical appraisal of health literature SBCM, Joint Program – Riyadh 20
Section 4:
Animal studies
Critical appraisal of health literature SBCM, Joint Program – Riyadh
Reporting guidelines
Critical appraisal of health literature SBCM, Joint Program – Riyadh 22
Critical appraisal tools
Critical appraisal of health literature SBCM, Joint Program – Riyadh 23
SYRCLE tool
SYstematic Review Centre for Laboratory animal
Experimentation tool
Critical appraisal of health literature SBCM, Joint Program – Riyadh 24
Take home messages
Critical appraisal of health literature SBCM, Joint Program – Riyadh
• Reporting guidelines compel the authors to stick
to a standard format
• However, they do not ensure validity and
reliability of the study findings
• For this critical appraisal tools are required
25
Thank you!
Email your queries to sarizwan1986@outlook.com

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Use of checklists in critical appraisal of health literature