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Riki CV HSR format

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Riki CV HSR format

  1. 1. Dr Riccardo Magistroni Tel: 059 422-2866 -4116 Divisione di Nefrologia Dialisi e Trapianto Renale , Policlinico di Modena, Università di Modena 1 Dr. Riccardo Magistroni CURRICULUM VITAE Date of preparation : 18 October 2015 Personal Data : Surname: Magistroni Name: Riccardo Place of birth: Bologna, Italy Citizenship Italian Mail address: Divisione di Nefrologia, Dialisi e Trapianto Renale, Policlinico di Modena V.del Pozzo 71 41100 Modena Telephone: 059 4224135; 4224116; 4224175 Telefax: 059.4222167 E-mail: riccardo.magistroni@unimore.it WORK EXPERIENCE July 2014 – until now Assistant Professor, “Dipartimento Chirurgico, Medico, Odontoiatrico e di Scienze Morfologiche con Interesse Trapiantologico, Oncologico e di Medicina Rigenerativa” , Division of Nephrology. University of Modena and Reggio Emilia Modena, Italy Associate Research Scientist, Department of Internal Medicine, Division of Nephrology Columbia University New York, NY Jan 2005 – June 2014 Assistant Professor with Clinical Integration, “Dipartimento Chirurgico, Medico, Odontoiatrico e di Scienze Morfologiche con Interesse Trapiantologico, Oncologico e di Medicina Rigenerativa”, Division of Nephrology. University of Modena and Reggio Emilia Modena, Italy Nov 2004 –Dic 2004 Staff Nephrologist, Division of Nephrology Azienda ospedaliero Universitaria Policlinico di Modena Modena, Italy TRAINING AND COURSES July 2014 – Present Columbia University, Department of Medicine New York, NY Division of Nephrology
  2. 2. Dr Riccardo Magistroni Tel: 059 422-2866 -4116 Divisione di Nefrologia Dialisi e Trapianto Renale , Policlinico di Modena, Università di Modena 2 Postdoctoral Research Fellow, Mentor: Ali G. Gharavi. Field: Nephrology/Genetics. During this period the researcher worked on the association analysis of rare and common variants, collected by Genome Wide Exome Sequencing and Exome Microarray Genotyping, in IgA Nephropathy. Furthermore Dr Riccardo Magistroni participated to the project of Precision Medicine in Nephrology of the Columbia University based on Exome Sequencing Technology. Jan 2002 – Nov 2002 University of Toronto Toronto, Canada Division of Nephrology, General Hospital Postdoctoral Research Fellow, Mentor: York Pei. Field : Nephrology/Genetics. During this period the researcher worked on the genotype – phenotype correlation of Autosomal Dominant Polycystic Kidney Disease. Furthermore he contributed to a project of positional cloning by linkage analysis in familial IgA Nephropathy. Sep 1999- Oct 2004 University of Modena and Reggio Emilia Modena, Italy Division of Nephrology Resident/Fellow in Nephrology Sep 1993 - Sep1999 University of Modena and Reggio Emilia Modena, Italy Division of Biochemical, Department of Biomedical Sciences, Mentor. Professor Sergio Ferrari. As medical student he learned the main techniques and strategies of research in molecular biology: PCR, Northern Blot, Southern Blot, Western Blot, Microsatellites Analysis, DNA Sanger Sequencing. EDUCATION Sep 1993 – Sep 1999 University of Modena and Reggio Emilia Modena, Italy Faculty of Medicine and Surgery MD degree at University Medical School, Sep 1999 Sep 1988 – Jul 1992 L.A. Muratori Liceo Modena, Italy High school degree : ‘Maturità Classica’ LICENSURE Sep 1999 Medical Licence Italy ADDITIONAL TRAINING AND ADVANCED COURSES Jun 2015 Genetic Association Course With Application to Sequence and Genotype Data Max Delbruck Center for Molecular Medicine – Berlin, Germany Jan 2010- Dic 2010 Advanced Course in “Statistics applied to clinical questions”
  3. 3. Dr Riccardo Magistroni Tel: 059 422-2866 -4116 Divisione di Nefrologia Dialisi e Trapianto Renale , Policlinico di Modena, Università di Modena 3 University of Modena and Reggio Emilia Modena, Italy Sep 2006- May2007 Advanced Course in Evidence Based Medicine and Methodology of Health Research. University of Modena and Reggio Emilia Modena, Italy April 11-13, 2002: “II Course in genetics and renal disorders”, Sestri Levante (Genova, Italy). PROFESSIONAL ORGANIZATIONS, SOCIETIES AND SERVICE Memberships 2013 – 2014: American Society of Nephrology. 2004 – present: Italian Society of Nephrology. Ad hoc reviewer 2010 – present Journal of Nephrology FELLOWSHIP AND GRANT SUPPORT 2015 Inhibition of Glycolysis by 2-Deoxy-D-Glucose as a Therapeutic Strategy for Polycystic KidneyDisease. Phase I Clinical Trial -Year 2015 – project code RF-2013-02356802. Italian Ministry of Health Principal Investigator : Dr.Riccardo Magistroni (Istituto San Raffaele) Groups Collaborating : Dr.ssa Alessandra Boletta (Istituto San Raffaele) Dr. Marco Lenonell (Azienda Ospedaliero Universitaria Policlinico di Modena) Dr. Mariano Capistrano (Presidio Ospedaliero di Montichiari dell'Azienda Spedali Civili di Brescia) Total funding : : € 422.516 2008 Autosomal Dominant Polycystic Kidney Disease: from the clinic to the cellular and molecular analysis: multidisciplinar approach for a diagnostic and prognostic evaluation. RESEARCH PROJECT -Year 2007 - prot. 2007FJRB7H. Italian Ministry of University and Research Principal Investigator : Riccardo Magistroni (Università di Modena e Reggio Emilia) Groups Collaborating : Maurizio Ferrari (Laboraf, Università Vita- Salute San Raffaele)
  4. 4. Dr Riccardo Magistroni Tel: 059 422-2866 -4116 Divisione di Nefrologia Dialisi e Trapianto Renale , Policlinico di Modena, Università di Modena 4 Alessandra Boletta (Dipartimento di Biologia Molecolare e Genomica Funzionale, Ospedale San Raffaele) Laura del Senno (Dipartimento di Biologia Molecolare, Università degli Studi di Ferrara) Total funding : € 164.770 2007 Quantitative and functional analysis of PKD1 and PKD2 gene expressed proteins: development and validation of a new diagnostic test widely applicable in clinical practice of Autosomal Dominant Polycystic Kidney Disease (ADPKD). Research Program Regione-Università 2007-2009 Area 1a – Innovative Research Regione Emilia Romagna, Italy Principal Investigator : Laura del Senno (Dipartimento di Biologia Molecolare, Università degli Studi di Ferrara) Groups Collaborating : Riccardo Magistroni (Università di Modena e Reggio Emilia) Luigi Catizone (Divisione di Nefrologia, Ospedale S’Anna di Ferrara) Total funding : € 215.000 2004 Membranous glomerulonephritis: researching prognostic factors for treatment efficacy by urine and renal biopsy proteomic analysis. RESEARCH PROJECT -Year 2004 - prot. 2004064212. Italian Ministry of University and Research COMMERCIAL COLLABORATION 2004 – 2010 Collaboration on clinical trial with Otsuka Pharmaceutical as Principal Investigator : “A phase 3, Multi-center, Double Blind, Placebo- controled, Parallel-arm Trial to Determine Long Term Safety and Efficacy of Oral Tolvaptan Tablet Regimens in Adult Subjects with Autosomal Dominant Polycystic Kidney Disease” Protocol No. 156- 04-251; EudraCT No. 2006-002768-24 Total turnover : € 126.785,00+IVA 2011 – present Collaboration on clinical trial with Otsuka Pharmaceutical as Principal Investigator: “Multi-center, Open-label, Extension Study to Evaluate the Long-term Efficacy and Safety of Oral Tolvaptan Tablet Regimens in Subjects with Autosomal Dominant Polycystic Kidney Disease (ADPKD)” Protocol: 156-08-271 ; EudraCT n: 2010-018401-10 Total turnover until now: € 77.253.17 +IVA 2012 – present Collaboration on clinical trial with Otsuka Pharmaceutical as Principal Investigator: ““A Multi-center, Longitudinal, Observational Study of Patients with Autosomal Dominant Polycystic Kidney Disease
  5. 5. Dr Riccardo Magistroni Tel: 059 422-2866 -4116 Divisione di Nefrologia Dialisi e Trapianto Renale , Policlinico di Modena, Università di Modena 5 (ADPKD) to Establish the Rate, Characteristics, and Determinants of Disease Progression” Protocol:156-10-291 ; Total turnover (expected): € 75.000 +IVA 2013 – present member of the Advisory Board for Otsuka Pharmaceutical Europe Ltd (OPEL) Autosomal dominant polycystic kidney disease Focus Group 4: Dosing and Titration (tolvaptan). 2014 – present member of the Advisory Board for Otsuka Pharmaceutical Italia : “Gruppo di discussione per la implementazione clinica di Tolvaptan nel trattamento di ADPKD” TEACHING EXPERIENCE AND RESPONSIBILITIES Jan 2005 – present University of Modena and Reggio Emilia Modena, Italy Medical School Course of Nephrology Jan 2005 – present University of Modena and Reggio Emilia Modena, Italy Nephrology Residency School Course of Glomerulonephrites and Renal Genetic Diseases Sep 2012 – Mar 2013 University of Modena and Reggio Emilia Modena, Italy Glomerular and Renal Genetic Disease Course Master of Renal Dietistic. Academic Master of level I. Sep 2011 – present University of Modena and Reggio Emilia Modena, Italy School of Medical Specialties - Dietistic Course of Nephrology Jan 2005 – Aug 2011 University of Modena and Reggio Emilia Modena, Italy Medical School Clinical Methodology
  6. 6. Dr Riccardo Magistroni Tel: 059 422-2866 -4116 Divisione di Nefrologia Dialisi e Trapianto Renale , Policlinico di Modena, Università di Modena 6 PUBLICATIONS Original, Peer Reviewed Articles 1. Magistroni R, D'Agati VD, Appel GB, Kiryluk K. New developments in the genetics, pathogenesis, and therapy of IgA nephropathy. Kidney Int 2015 IF = 8.563 2. Turco D, Severi S, Mignani R, Aiello V, Magistroni R, Corsi C. Reliability of Total Renal Volume Computation in Polycystic Kidney Disease From Magnetic Resonance Imaging. Acad Radiol 2015 IF = 1.751 3. Vergano L, Loiacono E, Albera R, Coppo R, Camilla R, Peruzzi L, Amore A, Donadio ME, Chiale F, Boido A, Mariano F, Mazzucco G, Ravera S, Cancarini G, Magistroni R, Beltrame G, Rollino C, Stratta P, Quaglia M, Bergia R, Cravero R, Cusinato S, Benozzi L, Savoldi S, Licata C. Can tonsillectomy modify the innate and adaptive immunity pathways involved in IgA nephropathy? J Nephrol 2014 IF = 1.454 4. Kiryluk K, Li Y, Scolari F, Sanna-Cherchi S, Choi M, Verbitsky M, Fasel D, Lata S, Prakash S, Shapiro S, Fischman C, Snyder HJ, Appel G, Izzi C, Viola BF, Dallera N, Del Vecchio L, Barlassina C, Salvi E, Bertinetto FE, Amoroso A, Savoldi S, Rocchietti M, Amore A, Peruzzi L, Coppo R, Salvadori M, Ravani P, Magistroni R, Ghiggeri GM, Caridi G, Bodria M, Lugani F, Allegri L, Delsante M, Maiorana M, Magnano A, Frasca G, Boer E, Boscutti G, Ponticelli C, Mignani R, Marcantoni C, Di Landro D, Santoro D, Pani A, Polci R, Feriozzi S, Chicca S, Galliani M, Gigante M, Gesualdo L, Zamboli P, Battaglia GG, Garozzo M, Maixnerova D, Tesar V, Eitner F, Rauen T, Floege J, Kovacs T, Nagy J, Mucha K, Paczek L, Zaniew M, Mizerska-Wasiak M, Roszkowska-Blaim M, Pawlaczyk K, Gale D, Barratt J, Thibaudin L, Berthoux F, Canaud G, Boland A, Metzger M, Panzer U, Suzuki H, Goto S, Narita I, Caliskan Y, Xie J, Hou P, Chen N, Zhang H, Wyatt RJ, Novak J, Julian BA, Feehally J, Stengel B, Cusi D, Lifton RP, Gharavi AG. Discovery of new risk loci for IgA nephropathy implicates genes involved in immunity against intestinal pathogens. Nat Genet 2014; 46: 1187-1196 IF = 29.352 5. Corsi C, Mignani R, Turco D, Magistroni R, Severi S. Comment on the paper: 'novel approach to estimate kidney and cyst volumes using mid-slice magnetic resonance images in polycystic kidney disease'. Am J Nephrol 2014; 39: 163-164 IF = 2.669 6. Murtas C, Bruschi M, Candiano G, Moroni G, Magistroni R, Magnano A, Bruno F, Radice A, Furci L, Argentiero L, Carnevali ML, Messa P, Scolari F, Sinico RA, Gesualdo L, Fervenza FC, Allegri L, Ravani P, Ghiggeri GM. Coexistence of different circulating anti-podocyte antibodies in membranous nephropathy. Clin J Am Soc Nephrol 2012; 7: 1394-1400 IF = 5.068
  7. 7. Dr Riccardo Magistroni Tel: 059 422-2866 -4116 Divisione di Nefrologia Dialisi e Trapianto Renale , Policlinico di Modena, Università di Modena 7 7. Cavazzini F and Magistroni R, Furci L, Lupo V, Ligabue G, Granito M, Leonelli M, Albertazzi A, Cappelli G. Identification and characterization of a new autoimmune protein in membranous nephropathy by immunoscreening of a renal cDNA library. PLoS One 2012; 7: e48845 IF = 3.73 8. Magistroni R, Cantu M, Ligabue G, Masellis M, Spisni E, Furci L, Lupo V, Genovese F, Cavazzini F, Albertazzi A. Interstitial fluid obtained from kidney biopsy as new source of renal biomarkers. J Nephrol 2011; 24: 329-337 IF = 1.703 9. Gharavi AG, Kiryluk K, Choi M, Li Y, Hou P, Xie J, Sanna-Cherchi S, Men CJ, Julian BA, Wyatt RJ, Novak J, He JC, Wang H, Lv J, Zhu L, Wang W, Wang Z, Yasuno K, Gunel M, Mane S, Umlauf S, Tikhonova I, Beerman I, Savoldi S, Magistroni R, Ghiggeri GM, Bodria M, Lugani F, Ravani P, Ponticelli C, Allegri L, Boscutti G, Frasca G, Amore A, Peruzzi L, Coppo R, Izzi C, Viola BF, Prati E, Salvadori M, Mignani R, Gesualdo L, Bertinetto F, Mesiano P, Amoroso A, Scolari F, Chen N, Zhang H, Lifton RP. Genome-wide association study identifies susceptibility loci for IgA nephropathy. Nat Genet 2011; 43: 321-327 IF = 35.532 10. Bruschi M, Carnevali ML, Murtas C, Candiano G, Petretto A, Prunotto M, Gatti R, Argentiero L, Magistroni R, Garibotto G, Scolari F, Ravani P, Gesualdo L, Allegri L, Ghiggeri GM. Direct characterization of target podocyte antigens and auto-antibodies in human membranous glomerulonephritis: Alfa-enolase and borderline antigens. J Proteomics 2011; 74: 2008-2017 IF = 4.878 11. Papale M, Di Paolo S, Magistroni R, Lamacchia O, De Mattia A, Teresa Rocchetti M, Furci L, Pasquali S, De Cosmo S, Cignarelli M, Gesualdo L. Urine Proteome Analysis May Allow Non-Invasive Differential Diagnosis of Diabetic Nephropathy. Diabetes Care 2010 IF = 7.141 12. Magistroni R, Cantu M, Ligabue G, Masellis M, Spisni E, Furci L, Lupo V, Genovese F, Cavazzini F, Albertazzi A. Interstitial fluid obtained from kidney biopsy as new source of renal biomarkers. J Nephrol 2010 IF = 1.623 13. Liu M, Shi S, Senthilnathan S, Yu J, Wu E, Bergmann C, Zerres K, Bogdanova N, Coto E, Deltas C, Pierides A, Demetriou K, Devuyst O, Gitomer B, Laakso M, Lumiaho A, Lamnissou K, Magistroni R, Parfrey P, Breuning M, Peters DJ, Torra R, Winearls CG, Torres VE, Harris PC, Paterson AD, Pei Y. Genetic variation of DKK3 may modify renal disease severity in ADPKD. J Am Soc Nephrol 2010; 21: 1510-1520 IF = 8.288 14. Limardo M, Imbasciati E, Ravani P, Surian M, Torres D, Gregorini G, Magistroni R, Casellato D, Gammaro L, Pozzi C. Pregnancy and progression of IgA nephropathy: results of an Italian multicenter study. Am J
  8. 8. Dr Riccardo Magistroni Tel: 059 422-2866 -4116 Divisione di Nefrologia Dialisi e Trapianto Renale , Policlinico di Modena, Università di Modena 8 Kidney Dis 2010; 56: 506-512 IF = 5.242 15. Pei Y, Obaji J, Dupuis A, Paterson AD, Magistroni R, Dicks E, Parfrey P, Cramer B, Coto E, Torra R, San Millan JL, Gibson R, Breuning M, Peters D, Ravine D. Unified criteria for ultrasonographic diagnosis of ADPKD. J Am Soc Nephrol 2009; 20: 205-212 IF = 7.505 16. Magistroni R, Ligabue G, Lupo V, Furci L, Leonelli M, Manganelli L, Masellis M, Gatti V, Cavazzini F, Tizzanini W, Albertazzi A. Proteomic analysis of urine from proteinuric patients shows a proteolitic activity directed against albumin. Nephrol Dial Transplant 2009; 24: 1672-1681 IF = 3.306 17. Brezzi B, Del Prete D, Lupo A, Magistroni R, Gomez-Lira M, Bernich P, Anglani F, Mezzabotta F, Turco A, Furci L, Ceol M, Antonucci F, Abaterusso C, Bonfante L, D'Angelo A, Albertazzi A, Gambaro G. Primary IgA nephropathy is more severe in TGF-beta1 high secretor patients. J Nephrol 2009; 22: 747-759 IF = 1.252 18. Paterson AD, Liu XQ, Wang K, Magistroni R, Song X, Kappel J, Klassen J, Cattran D, St George-Hyslop P, Pei Y. Genome-wide linkage scan of a large family with IgA nephropathy localizes a novel susceptibility locus to chromosome 2q36. J Am Soc Nephrol 2007; 18: 2408-2415 IF = 7.111 19. Pereira TV, Nunes AC, Rudnicki M, Magistroni R, Albertazzi A, Pereira AC, Krieger JE. Influence of ACE I/D gene polymorphism in the progression of renal failure in autosomal dominant polycystic kidney disease: a meta-analysis. Nephrol Dial Transplant 2006; 21: 3155-3163 IF = 3.154 20. Magistroni R, Furci L, Leonelli M, Masellis M, Ligabue G, Lucchi L, Lupo A, Brezzi B, Gambaro G, Manganelli L, Pedrazzi G, Ricardi M, Bormioli L, Albertazzi A. A validated model of disease progression in IgA nephropathy. J Nephrol 2006; 19: 32-40 IF = 1.448 21. Paterson AD, Magistroni R, He N, Wang K, Johnson A, Fain PR, Dicks E, Parfrey P, St George-Hyslop P, Pei Y. Progressive loss of renal function is an age-dependent heritable trait in type 1 autosomal dominant polycystic kidney disease. J Am Soc Nephrol 2005; 16: 755-762 IF = 7.240 22. Magistroni R, Manfredini P, Furci L, Ligabue G, Martino C, Leonelli M, Scapoli C, Albertazzi A. Epidermal growth factor receptor polymorphism and autosomal dominant polycystic kidney disease. J Nephrol 2003; 16: 110-115 IF = 1.025
  9. 9. Dr Riccardo Magistroni Tel: 059 422-2866 -4116 Divisione di Nefrologia Dialisi e Trapianto Renale , Policlinico di Modena, Università di Modena 9 23. Magistroni R, He N, Wang K, Andrew R, Johnson A, Gabow P, Dicks E, Parfrey P, Torra R, San-Millan JL, Coto E, Van Dijk M, Breuning M, Peters D, Bogdanova N, Ligabue G, Albertazzi A, Hateboer N, Demetriou K, Pierides A, Deltas C, St George-Hyslop P, Ravine D, Pei Y. Genotype-renal function correlation in type 2 autosomal dominant polycystic kidney disease. J Am Soc Nephrol 2003; 14: 1164-1174 IF = 7.499 24. Del Prete D, Gambaro G, Lupo A, Anglani F, Brezzi B, Magistroni R, Graziotto R, Furci L, Modena F, Bernich P, Albertazzi A, D'Angelo A, Maschio G. Precocious activation of genes of the renin-angiotensin system and the fibrogenic cascade in IgA glomerulonephritis. Kidney Int 2003; 64: 149-159 IF = 5.302 Chapters of books 1. Furci L, Magistroni R, Albertazzi A. Le Sindromi Renali. Trattato italiano di Medicina Interna 6° edizione. Teodori, Editor: Universo (2000). pp 829-837 2. P.F. Calmieri, R.Magistroni, A.Albertazzi. Le Nefropatie Glomerulari: glomerulonefriti primitive; glomerulonefriti secondarie. Trattato di Medicina Interna Vol VII. Malattie del Rene, delle Vie Urinarie e dell’Apparato Genitale Maschile. Alberto Albertazzi, Massimo Porena. Editore Piccin(2003). pp115-147. New York, 18 October 2015 Riccardo Magistroni, MD

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