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Research Facilities

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Research Facilities

  1. 1. Research Facilities & Resources
  2. 2. Overview <ul><li>Community-based research clinic in San </li></ul><ul><li>Gabriel valley </li></ul><ul><li>Well-developed infrastructure and facilities </li></ul><ul><li>DOM resource administered by Division of </li></ul><ul><li>Geriatrics </li></ul><ul><li>Growing links with other DOM and SOM core research resources </li></ul>
  3. 3. RCA 10 Pasadena South El Monte Eagle Rock 710 110 210 134 Monterey Park Temple City Arcadia South Pasadena San Gabriel Altadena Highland Park San Marino Rosemead Boyle Heights UCLA LA County-USC Hosp
  4. 4. Facilities <ul><li>Clinic space: 2 suites of exam/procedure rooms </li></ul><ul><ul><li>Large: 8 pt rooms; Small: 6 pt rooms </li></ul></ul><ul><ul><li>Each has scales, stadiometers, sphygs, phlebotomy station, locker room </li></ul></ul><ul><li>Snack room </li></ul><ul><li>Kitchen for food storage </li></ul>
  5. 5. Facilities <ul><li>Specialized technologies </li></ul><ul><ul><li>Ultrasound </li></ul></ul><ul><ul><li>ECG </li></ul></ul><ul><ul><li>Fundus photography </li></ul></ul><ul><ul><li>DEXA (Hologic 4500) </li></ul></ul><ul><li>Secure medication storage </li></ul><ul><ul><li>Regular inventory </li></ul></ul><ul><ul><li>Experienced with automatic phone dispensing </li></ul></ul>
  6. 6. Facilities <ul><li>Laboratory </li></ul><ul><ul><li>Refrigerated centrifuge </li></ul></ul><ul><ul><li>-20 °C and –80 °C storage freezers (limited) </li></ul></ul><ul><ul><li>CLIA certified </li></ul></ul>
  7. 7. <ul><li>Educational </li></ul><ul><ul><li>Flexibly configured classrooms </li></ul></ul><ul><ul><li>Grouped workstations for 6 participants </li></ul></ul><ul><ul><li>Audiovisual equipment </li></ul></ul><ul><li>Telephone / in-person surveying </li></ul><ul><ul><li>6-line phone bank available </li></ul></ul><ul><li>Community-based data collection </li></ul><ul><ul><li>Headquarter staff with easier access to community sites such as schools and senior centers </li></ul></ul><ul><ul><li>Offices linked to UCLA infrastructure </li></ul></ul>Facilities
  8. 8. <ul><li>Experienced study coordinators, data collectors, and recruiters </li></ul><ul><li>Many staff bilingual (Spanish, Mandarin, Cantonese, Vietnamese, Farsi) </li></ul><ul><li>Certified phlebotomists, medical assistants, laboratory assistants & DEXA technicians </li></ul>Staff Resources
  9. 9. <ul><li>Data processing and management </li></ul><ul><li>Regulatory and fund management </li></ul><ul><li>Nutritionists </li></ul><ul><li>Specialized software development (Available through OAIC-ROC) </li></ul>Staff Resources
  10. 10. <ul><li>2 passenger vans & staff drivers for transporting participants </li></ul><ul><li>Free parking </li></ul><ul><li>Handicap access </li></ul><ul><li>Convenient public transportation </li></ul>Accessibility
  11. 11. Research Support Services <ul><li>Initial evaluation meeting </li></ul><ul><ul><li>Feasibility for RCA, resource needs/availability, costs </li></ul></ul><ul><li>Proposal preparation </li></ul><ul><ul><li>Operations budget & justification, boilerplate text </li></ul></ul><ul><li>Project implementation </li></ul><ul><ul><li>Staffing, training, certification </li></ul></ul><ul><ul><li>Coordination with other RCA projects (staff, space, transportation, other resources/equipment) </li></ul></ul><ul><ul><li>IRB correspondence </li></ul></ul>
  12. 12. <ul><li>Westwood GCRC/proposed CTSI </li></ul><ul><li>Office of Clinical Trials </li></ul><ul><li>UCLA Older Adults Independence Center </li></ul><ul><ul><li>4 research cores: Research Operations, Recruitment, Analysis/Cost-Effectiveness, Inflammatory Biology </li></ul></ul><ul><li>In development: </li></ul><ul><ul><li>Resource Center for Minority Aging Research </li></ul></ul><ul><ul><li>UCLA-Harbor GCRC </li></ul></ul>Linkages
  13. 13. <ul><li>Through OAIC Research Operations Core </li></ul><ul><li>Help with quality control flow </li></ul><ul><ul><li>Development of protocols & manuals </li></ul></ul><ul><ul><li>Design training and certification sessions </li></ul></ul><ul><ul><li>Data flow and review analysis </li></ul></ul><ul><li>Data entry application and design </li></ul><ul><ul><li>Analysis of data forms for collection & entry </li></ul></ul><ul><ul><li>Pepper Informatics </li></ul></ul>Data Management Expertise
  14. 14. Current Studies <ul><li>Multi-Ethnic Study of Atherosclerosis (MESA) (PI: Karol Watson) + affiliated ancillary studies </li></ul><ul><ul><li>Longitudinal study of 4 ethnic groups </li></ul></ul><ul><ul><li>Observational study started in 2001 </li></ul></ul><ul><ul><li>Physical exam, interviews, imaging, phlebotomy </li></ul></ul><ul><ul><li>Ancillary studies consist of similar exams </li></ul></ul><ul><li>MESA Air (PI:Adrian Casillas) </li></ul><ul><ul><li>Original MESA cohort plus new Riverside & Santa Monica residents, 2006-2007 </li></ul></ul><ul><ul><li>Exam similar to MESA, adding air quality monitoring </li></ul></ul>
  15. 15. Current Studies <ul><li>Diabetes Prevention Project – Outcome Study (DPPOS) (PI: Karol Watson) </li></ul><ul><ul><li>Originally randomized trial for diabetes prevention through metformin or lifestyle intervention </li></ul></ul><ul><ul><li>Physical exam, interviews, phlebotomy </li></ul></ul><ul><ul><li>Behavior interventions and health education </li></ul></ul><ul><li>Diabetes education programs (PI: Preethi Srikanthan) </li></ul><ul><ul><li>Two small pilots examining feasability of computer-based education modules to Mexican-Americans </li></ul></ul>
  16. 16. Current Studies <ul><li>Pharmaceutical trials (PIs: Karol Watson & Christine Darwin) </li></ul><ul><ul><li>Trials for a variety of sponsors (Novartis, Novo Nordisc) targeting outcomes related to diabetes or cardiovascular health </li></ul></ul><ul><ul><li>Dispense medication & conduct physical exams as indicated by protocol </li></ul></ul>
  17. 17. Costs <ul><li>Costs competitive with on-campus costs </li></ul><ul><ul><li>On campus 54% IDC ~ off campus facility fees + 26% IDC </li></ul></ul><ul><ul><li>Direct personnel costs are fee for service (e.g., interviewers, phlebotomists) </li></ul></ul><ul><li>Small projects may have facility fees waived </li></ul>
  18. 18. Summary <ul><li>Location </li></ul><ul><ul><li>Access to diversity of ethnic communities </li></ul></ul><ul><li>Facilities </li></ul><ul><ul><li>Clinic & classroom space, phlebotomy, lab w/ temporary specimen storage, ultrasound, DEXA, ECG </li></ul></ul><ul><li>Staff </li></ul><ul><ul><li>Experienced multi-lingual project directors and research staff, data management staff and software </li></ul></ul>
  19. 19. For further information, contact Heather McCreath, PhD (310) 267-0848 e-mail: [email_address] 330 S. Garfield, Suite 308 Alhambra, CA 91801 (626) 979-4920

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