Part A: Module A8
Session 8
Skin Lesions
Part A/Module2A/Session 8
Skin lesions
 80-100% of persons livng with HIV/AIDS
develop dermatological conditions
 May be...
Part A/Module2A/Session 8
Etiologies of Skin Lesions
 Bacterial infection: Streptococcus aureus, streptococcus
species, T...
Part A/Module2A/Session 8
Clues from presentation
 Warm, inflamed, painful and/or fluctuant---a
bacterial infection
 Dis...
Part A/Module2A/Session 8
Possible Differentials: Skin Conditions
Bacterial Skin abscess or pyomyositis
Furunculosis or fo...
Part A/Module2A/Session 8
Skin Conditions, continued.
Prurigo and other skin conditions
 Drug eruptions
 HIV-associated ...
Part A/Module2A/Session 8
Prurigo Nodularis
Part A/Module2A/Session 8
Prurigo
Part A/Module2A/Session 8
Psoriasis
Part A/Module2A/Session 8
Fixed drug eruption on cotrimoxazole
Part A/Module2A/Session 8
Stevens-Johnson in patient on
thiocetazone: severe mucositis lesions
Part A/Module2A/Session 8
Seborrheic Dermatitis
Part A/Module2A/Session 8
Non-Hodgkins Lymphoma
 Fever, night sweats, unexplained weight loss
 Lymphadenopathy, splenome...
Part A/Module2A/Session 8
Central Nervous System Lymphoma
 End-stage complication (CD4<100)
 IF no biopsy available, fai...
Part A/Module2A/Session 8
Cryptococcosi
s
Part A/Module2A/Session 8
Herpes
Zoster--
Shingles
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Session 8

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Session 8

  1. 1. Part A: Module A8 Session 8 Skin Lesions
  2. 2. Part A/Module2A/Session 8 Skin lesions  80-100% of persons livng with HIV/AIDS develop dermatological conditions  May be very disabling, disfiguring and even life-threatening
  3. 3. Part A/Module2A/Session 8 Etiologies of Skin Lesions  Bacterial infection: Streptococcus aureus, streptococcus species, Treponema pallidum,  Bartonella species   Mycobacterial infection: M. tuberculosis, M. Avium complex  Viral infection: Herpes simplex and zoster virus, molluscum contagiosum, condylomata accuminata  Infestations: Scabies  Fungal infection: seborrheic dermatitis, tinea corporis, pityriasis versicolor, Cryptococcus neoformans, Histoplasma capsulatum, Candida species  
  4. 4. Part A/Module2A/Session 8 Clues from presentation  Warm, inflamed, painful and/or fluctuant---a bacterial infection  Discolored skin patches----a fungal infection or Kaposi’s sarcoma  Localized eruptions or localized pimple-like swellings--- a viral infection  Prurigo/urticaria, macular, maculopapular or scaly lesions-- classified as other skin conditions, including drug eruptions, seborrhea, psoriasis, and scabies
  5. 5. Part A/Module2A/Session 8 Possible Differentials: Skin Conditions Bacterial Skin abscess or pyomyositis Furunculosis or folliculitis Hydradenitis suppurativa Impetigo Kaposi’s Sarcoma Fungal Tinea, Candidiasis Viral Herpes Simplex Condylomata acuminata Herpes zoster Molluscum contagiosum
  6. 6. Part A/Module2A/Session 8 Skin Conditions, continued. Prurigo and other skin conditions  Drug eruptions  HIV-associated rash  itchy generalized maculo-papular rash  Seborrheic dermatitis or generalized erythroderma  Psoriasis  Scabies  Other dermatoses
  7. 7. Part A/Module2A/Session 8 Prurigo Nodularis
  8. 8. Part A/Module2A/Session 8 Prurigo
  9. 9. Part A/Module2A/Session 8 Psoriasis
  10. 10. Part A/Module2A/Session 8 Fixed drug eruption on cotrimoxazole
  11. 11. Part A/Module2A/Session 8 Stevens-Johnson in patient on thiocetazone: severe mucositis lesions
  12. 12. Part A/Module2A/Session 8 Seborrheic Dermatitis
  13. 13. Part A/Module2A/Session 8 Non-Hodgkins Lymphoma  Fever, night sweats, unexplained weight loss  Lymphadenopathy, splenomegaly, pancytopenia, bowel obstruction, ascites, cranial nerve lesions, spinal cord suppression, nerve root lesions, cutaneous, testicular and lung mass lesions  Prognosis poor when CD4 is <100  Treatment is chemotherapy
  14. 14. Part A/Module2A/Session 8 Central Nervous System Lymphoma  End-stage complication (CD4<100)  IF no biopsy available, failure of trial of treatment for toxo considered diagnostic of CNS lymphoma  Irradiation is palliative, no cytotoxic therapy  Survival after diagnosis limited to a few months
  15. 15. Part A/Module2A/Session 8 Cryptococcosi s
  16. 16. Part A/Module2A/Session 8 Herpes Zoster-- Shingles

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