Current PsoriasisCurrent Psoriasis
Situation in ChinaSituation in China
Zheng MinZheng Min ,, M.D.M.D.
Dermatology Departm...
 Practical organisation of Chinese
Psoriasis Network
 National projects
 opportunitis to develop international
collabor...
Chairman Prof. Zhu Xuejun,
Chinese Dermatologist Association
Six National Psoriasis Center
 Institute of Dermatology, Chinese Academy of
Medical Sciences and Peking Union Medical
Col...
Geographic Coverage of 46 hospitals in China
未覆盖区域
山西
贵州
四川
西藏
香港
台湾
 Practical organisation of Chinese
Psoriasis Network
 National projects
 opportunitis to develop international
collabor...
 World Psoriasis Day event
 Targeted Patients
Epidermological Investigation
 National Treatment Guideline
National proj...
Press conference focus on national psoriasis prevention and treatment on 29. Oct.
Prof. Zhu Xuejun, chairman of China Dermatologist Association, in Press conference in
International day of Psoriasis
•
Beijing
•
Shanghai
•
Hangzhou
46 hospitals in different cities of China
4879 cases of psoriasis
(2009.Nov.23-Dec. 12)
●
...
New Data 2009New Data 2009
 46 hospitals in China
 4879 cases of psoriasis vulgaris
 Male, 61.14%; Female, 38.86% ,
Mal...
 Family history of psoriasis: 22.84%
(1057/4628)
 62.53 % in first degree relatives62.53 % in first degree relatives
27....
Peak age of first onsetPeak age of first onset
male: 20~29 yearsmale: 20~29 years
female: 10~19 yearsfemale: 10~19 years
Z...
Psoriasis vulgaris may be a multigenicPsoriasis vulgaris may be a multigenic
inheritable disease and the geneticinheritabl...
Causative factorCausative factor
 Psychological factorPsychological factor
 Infection, wound
 Alcohol, diet, smoking, d...
Relapse and aggratateRelapse and aggratate
 Season, especially winter (83.36%)
 Psychological factor
 Pharyngolaryngiti...
Releave SeasonReleave Season
 Summer ( 90.56% )
 Spring
 Paracmasia: 14.06±37.93 m
Clinical Type of psoriasisClinical Type of psoriasis
in Chinain China
 Psoriasis vulgaris: 4489 ( 92.01% )
Guttae 26.09%
...
 19.67%: 932/4737 have accompanied
disease
 High blood pressure:
576 ( 12.16% )
 Diabetes: 237 ( 5.00% )
 Coronary hea...
ManagementManagement
Systemic therapy;Systemic therapy;
Topical therapy;Topical therapy;
Patient education.Patient educati...
 79.55% (3809/4788)79.55% (3809/4788)
 Traditional Chinese Medicine 89.47%Traditional Chinese Medicine 89.47%
AcitretinA...
Systemic treatmentSystemic treatment
 Methotrexate 7.5mg/weekMethotrexate 7.5mg/week
widespread plaque, senile personwide...
Topical therapyTopical therapy
 90.34% (4283/4741)90.34% (4283/4741)
 Topical steroids: 85.59%Topical steroids: 85.59%
V...
Physical therapyPhysical therapy
 26.54%: 124426.54%: 1244//46884688
 NB-UVBNB-UVB >> 50%50%
UVBUVB
PUVAPUVA
Insurance and treatment costsInsurance and treatment costs
 71.2% patients have a social medical71.2% patients have a soc...
Insurance and treatment costsInsurance and treatment costs
 In the past 2 years, 7.07% patients wereIn the past 2 years, ...
QOL
 18.73% patients were affected
severely, 29.45% moderately , and
37.56% slightly. Only 14.27% were
unaffected.
 13.3...
 Update our National Treatment
Guideline according to the new data
from evidence based medicine:
 National Disease Regis...
 Practical organisation of Chinese
Psoriasis Network
 National projects
 Opportunitis to develop international
collabor...
 Comparison study on the background
between Eastern and Western in
genetics and clinical pattern
background
 Some mechan...
THANK YOU !THANK YOU !
•
Beijing
•
Shanghai
•
Hangzhou
Zhejiang Univ. School ofZhejiang Univ. School of
Med.Med.
Current Psoriasis Situation in China
Current Psoriasis Situation in China
Current Psoriasis Situation in China
Current Psoriasis Situation in China
Current Psoriasis Situation in China
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Current Psoriasis Situation in China

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Current Psoriasis Situation in China

  1. 1. Current PsoriasisCurrent Psoriasis Situation in ChinaSituation in China Zheng MinZheng Min ,, M.D.M.D. Dermatology DepartmentDermatology Department Second HospitalSecond Hospital Zhejiang University, School of MedicineZhejiang University, School of Medicine 浙江大学医学院附属第二医院郑敏浙江大学医学院附属第二医院郑敏 PSORIASIS 2010 Congress of the Psoriasis International Network PARIS, July 1-4, 2010 Palais des Congrès
  2. 2.  Practical organisation of Chinese Psoriasis Network  National projects  opportunitis to develop international collaborations on specific topics  other issues
  3. 3. Chairman Prof. Zhu Xuejun, Chinese Dermatologist Association
  4. 4. Six National Psoriasis Center  Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College.Nanjing;  First Hospital Beijing Univerity.Beijing;  Second Hospital Zhejiang University.Hangzhou;  Huashan Hospital, Fudan University.Shanghai;  Xijing Hospital, Fourth Military Medical University; Xi’an ;  Peking Union Medical College Hospital.Beijing. Chinese Psoriasis Network
  5. 5. Geographic Coverage of 46 hospitals in China 未覆盖区域 山西 贵州 四川 西藏 香港 台湾
  6. 6.  Practical organisation of Chinese Psoriasis Network  National projects  opportunitis to develop international collaborations on specific topics  other issues
  7. 7.  World Psoriasis Day event  Targeted Patients Epidermological Investigation  National Treatment Guideline National projects
  8. 8. Press conference focus on national psoriasis prevention and treatment on 29. Oct.
  9. 9. Prof. Zhu Xuejun, chairman of China Dermatologist Association, in Press conference in International day of Psoriasis
  10. 10. • Beijing • Shanghai • Hangzhou 46 hospitals in different cities of China 4879 cases of psoriasis (2009.Nov.23-Dec. 12) ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ●● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ● ●
  11. 11. New Data 2009New Data 2009  46 hospitals in China  4879 cases of psoriasis vulgaris  Male, 61.14%; Female, 38.86% , Male : Female=1.57 : 1  Mean age 40.49±22.11
  12. 12.  Family history of psoriasis: 22.84% (1057/4628)  62.53 % in first degree relatives62.53 % in first degree relatives 27.72 % in second degree relatives27.72 % in second degree relatives 9.76 % in third degree relativesin third degree relatives Genetic epidemiologyGenetic epidemiology
  13. 13. Peak age of first onsetPeak age of first onset male: 20~29 yearsmale: 20~29 years female: 10~19 yearsfemale: 10~19 years Zhang XJ et al: Analyses of Genetic Epidemiology of Psoriasis Vulgaris Chinese Journal of Dermatology 2000;33(6):383-385.
  14. 14. Psoriasis vulgaris may be a multigenicPsoriasis vulgaris may be a multigenic inheritable disease and the geneticinheritable disease and the genetic factors play an important role in thefactors play an important role in the pathogenesis of psoriasis.pathogenesis of psoriasis. Zhang XJ et al: Analyses of Genetic Epidemiology of Psoriasis Vulgaris Chinese Journal of Dermatology 2000;33(6):383-385.
  15. 15. Causative factorCausative factor  Psychological factorPsychological factor  Infection, wound  Alcohol, diet, smoking, drug  Endocrine and metabolic diseaseEndocrine and metabolic disease
  16. 16. Relapse and aggratateRelapse and aggratate  Season, especially winter (83.36%)  Psychological factor  Pharyngolaryngitis or tonsillitisPharyngolaryngitis or tonsillitis  Alcohol and food  Medicine and smoking
  17. 17. Releave SeasonReleave Season  Summer ( 90.56% )  Spring  Paracmasia: 14.06±37.93 m
  18. 18. Clinical Type of psoriasisClinical Type of psoriasis in Chinain China  Psoriasis vulgaris: 4489 ( 92.01% ) Guttae 26.09% Plaque 57.01% Mix 16.91%  Psoriasis pustulosa: 169 ( 3.46% )  Psoriasis erythroderma: 79 ( 1.62% )  Psoriasis arthropathica: 142 例( 2.91% )。
  19. 19.  19.67%: 932/4737 have accompanied disease  High blood pressure: 576 ( 12.16% )  Diabetes: 237 ( 5.00% )  Coronary heart disease:149 ( 3.15% )  Hyperlipemia: 340 ( 7.18% )  Rheumatoid arthritis: 61 ( 1.29% ), ComorbiditiesComorbidities in psoriatic patientsin psoriatic patients
  20. 20. ManagementManagement Systemic therapy;Systemic therapy; Topical therapy;Topical therapy; Patient education.Patient education.
  21. 21.  79.55% (3809/4788)79.55% (3809/4788)  Traditional Chinese Medicine 89.47%Traditional Chinese Medicine 89.47% AcitretinAcitretin 22.06%22.06% MTX 5.64%MTX 5.64% Immunosupressants 14.02%Immunosupressants 14.02% Steroids 13.30%Steroids 13.30% Others 27.59%Others 27.59% Systemic treatmentSystemic treatment
  22. 22. Systemic treatmentSystemic treatment  Methotrexate 7.5mg/weekMethotrexate 7.5mg/week widespread plaque, senile personwidespread plaque, senile person  Acitretin 0.5mg/kg.dAcitretin 0.5mg/kg.d erythroderma and pustular psoriasiserythroderma and pustular psoriasis  Cyclosporin A 5mg/kg.d psoriasis arthritisCyclosporin A 5mg/kg.d psoriasis arthritis  Corticosteroids.Corticosteroids.  BiologicsBiologics  Alternative therapy TCMAlternative therapy TCM
  23. 23. Topical therapyTopical therapy  90.34% (4283/4741)90.34% (4283/4741)  Topical steroids: 85.59%Topical steroids: 85.59% Vitamin D3 analogue: 31.64%Vitamin D3 analogue: 31.64% Topical retinoids: 27.01%Topical retinoids: 27.01% Salicylic acid: 18.98%Salicylic acid: 18.98% Coal tar: 14.57%Coal tar: 14.57% Anthralin: 3.34%Anthralin: 3.34% Topical TCM: 23.67%Topical TCM: 23.67% Others: 25.40%Others: 25.40%
  24. 24. Physical therapyPhysical therapy  26.54%: 124426.54%: 1244//46884688  NB-UVBNB-UVB >> 50%50% UVBUVB PUVAPUVA
  25. 25. Insurance and treatment costsInsurance and treatment costs  71.2% patients have a social medical71.2% patients have a social medical insurance (non-commercial), andinsurance (non-commercial), and 7.43% patients attend other7.43% patients attend other commercial medical insurancecommercial medical insurance  In the past 6 months, about 29.84%In the past 6 months, about 29.84% went to see a dermatologist 6 times.went to see a dermatologist 6 times. The mean fees is $101±2000, andThe mean fees is $101±2000, and about $52±100 were paid by patientsabout $52±100 were paid by patients themselvesthemselves 。。
  26. 26. Insurance and treatment costsInsurance and treatment costs  In the past 2 years, 7.07% patients wereIn the past 2 years, 7.07% patients were accepted in the hospital and 0.21% were inaccepted in the hospital and 0.21% were in the hospital more than 6 times.the hospital more than 6 times.  The duration in the hospital isThe duration in the hospital is 27.26±46.27d27.26±46.27d ,, mean spent ismean spent is $1100±1200$1100±1200 ,, and the patients themselvesand the patients themselves have to pay $600±1000have to pay $600±1000
  27. 27. QOL  18.73% patients were affected severely, 29.45% moderately , and 37.56% slightly. Only 14.27% were unaffected.  13.31% patients’ family expenditure were affected greatly, 25.96% moderately, 38.90% slightly and 21.82% unaffected.
  28. 28.  Update our National Treatment Guideline according to the new data from evidence based medicine:  National Disease Registration;  National Epi Invetigation;  International co-operation. More to do
  29. 29.  Practical organisation of Chinese Psoriasis Network  National projects  Opportunitis to develop international collaborations on specific topics and other issues
  30. 30.  Comparison study on the background between Eastern and Western in genetics and clinical pattern background  Some mechanism study on traditional Chinese Medicine on psoriasis  …….
  31. 31. THANK YOU !THANK YOU ! • Beijing • Shanghai • Hangzhou
  32. 32. Zhejiang Univ. School ofZhejiang Univ. School of Med.Med.

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