INTRODUCTION
Fundamental unit of life
THE FIRST CELL WAS OBSERVED BY ROBERT Hooke (slice of corK)
That was dead and suberized cell wall
FIRST LIVING CELL WAS OBSERVED BY Antonie van Leeuwenhoek
GLYCOCALYX
OUTERMOST LAYER OF CELL
Carbohydrate molecules form a thin and loose covering over the entire
surface of the cell membrane called glycocalyx.
CELL MEMBRANE
Seperate extra cellular fluid to intra cellular fluid
Semipermeable in nature so ,freely permeable to fat soluble substances
Tipical thickness is about -75-110Å
Composition of membrane
Potein-55%
Lipid-40%
Carbohydrate -5%
STRUCTURE OF CELL MEMBRANE
DANIELLI-DAVSON MODEL-”SANDWICH OF LIPID”
UNIT MEMBRANE MODEL-JD ROBERTSON , GAVE STRUCTURAL MODEL ON THE BASIS
OF ELECTRON MICROSCOPY
FLUID MOSAIC MODEL – SINGER AND NICOLSON
This model explain about fluid nature of plasma membrane here MOSAIC is the
pattern produced by the protein present in the cell membrane
LIPID PRESENT IN CELL MEMBRANE ARE-1.Phospholipids 2. Cholesterol.
Protein molecules are classified into two categories:
1. Integral proteins 2. Peripheral protein
FUNCTION OF PROTEIN
Integral proteins provide the structural integrity of the cell membrane
Antigens: Some proteins act as antigens and induce the process of antibody
formation
Pump
Channel proteins
FUNCTION OF CELL MEMBRANE
Protective function
maintenance of shape and size of the cell
Excretory function
Selective permeability
Cytoplasm – Cytoplasm of the cell is the jellylike material formed by 80% of
water.
Provide medium for the various chemical reaction occurring in the cell
Cytoplasm is made up of two zones:
1. Ectoplasm:
2. Endoplasm
CELL ORGANELLES
MITOCHONDRION– membrane bound cytoplasmic organelle concerned with
production of energy.
The outer membrane is smooth contains various enzymes such as acetyl-CoA
synthetase and glycerolphosphate acetyltransferase.
The inner membrane is folded in the form of shelf-like inward projections
called cristae
Cristae contain many enzymes and other protein molecules which are
involved in respiration and synthesis of adenosine triphosphate (ATP)
FUNCTION OF MITOCHONDRIA-1.PRODUCTION OF ATP
2.Involve in the process of APOPTOSIS
Other functions of mitochondria include storage of calcium and detoxification
of ammonia in liver
NUCLEUS
Nuclear membrane is double layered and porous in nature.
Nucleoplasm -highly viscous fluid that forms the ground substance of the
nucleus. It is similar to cytoplasm present outside the nucleus
Nucleoplasm surrounds chromatin and nucleolus.
Chromatin –DNA HISTONE PROTEIN COMPLEX
Nucleolus- ribosomal factory
Function OF NUCLEUS
1. Control of all the cell activities that include metabolism, protein synthesis,
growth
2. Synthesis of RNA
3. Formation of subunits of ribosomes
4.Control of the cell division through genes
5.Storage of hereditary information
ENDOPLASMIC RETICULUM
Endoplasmic reticulum is a network of tubular and microsomal vesicular
structures
The endoplasmic reticulum forms the link between nucleus and cell
membrane by connecting the cell membrane with the nuclear membrane
Types of Endoplasmic Reticulum– 1.ROUGH ENDOPLASMIC RETICULUM.
2.SMOOTH ENDOPLASMIC RETICULUM
1.ROUGH ENDOPLASMIC RETICULUM-
endoplasmic reticulum with rough appearance, Rough appearance is due to
the attachment of granular ribosomes to its outer surface
FUNCTION OF ROUGH ENDOPLASMIC RETICULUM
1. Synthesis of proteins
2. Degradation of worn-out organelles
SMOOTH ENDOPLASMIC RETICULUM –It is the endoplasmic reticulum with
smooth appearance
FUNCTION OF SMOOTH ENDOPLASMIC RETICULUM
1. Synthesis of non-protein substance
2. Storage and metabolism of calcium
3.Catabolism and detoxification
GOLGI APPARATUS
Golgi complex is a membrane-bound organelle, involved in the
processing of proteins. It is present in all the cells except red blood
cells
It consists of 5 to 8 flattened membranous sacs called the cisternae
Functions of Golgi Apparatus
1.Processing of materials
2.Packaging of materials