Ruben A. Mesa, MD, FACP, Nicolaus Kröger, MD, Francesco Passamonti, MD, and Robyn M. Scherber, MD, discuss myeloproliferative neoplasms in this CME activity titled "Stories From the MPN Casebook: Expert Perspectives on Challenging Treatment Decisions in Polycythemia Vera and Myelofibrosis." For the full presentation, downloadable practice aids, monograph, complete CME information, and to apply for credit, please visit us at http://bit.ly/2Bf2yCv. CME credit will be available until December 27, 2018.