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LITERATURE REVIEW OF FEBRILE SEIZURES

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Introduction
Types of febrile seizures
Causes Of Febrile Seizures
Treatment
Aim & Objectives

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LITERATURE REVIEW OF FEBRILE SEIZURES

  1. 1. LITERATURE REVIEW OF FEBRILE SEIZURES Submitted By: Pankaj Kumar Maurya Roll no: 1438689 DEPARTMENT OF PHARMACY PRACTICE ISF COLLEGE OF PHARMACY, MOGA 1 Supervisor: Dr. Mandeep kaur Assistant Professor
  2. 2. Introduction Febrile seizures(FS) are defined as a convulsions that can happen during a fever (febrile means “feverish”). They affect kids 3 month to 6 year old. Febrile most common in babies of 12-18 months old. The seizures usually last for a few minutes and a fever above 100.4⁰F (38°C ) Types of febrile seizures Simple febrile seizures. Complex febrile seizers. 2
  3. 3. Introduction Simple febrile seizures are usually over in a few minutes. But in rare cases they can last up to 15 minutes. During this type of seizure, a child’s whole body convulse, shake and twitch eyes may role and she or he moan or become unconscious. Children sometime vomit or urinate on themselves during the convulsions. Complex febrile seizers can last more than 15 minutes or happen or then once in 24 hours. They may also involve movement or twitching of just one part of the body. Febrile stop on their own While the fever may continue for sometime. 3
  4. 4. Causes Of Febrile Seizures Infection :-Usually the fever that triggers are caused by a viral infection and less commonly by a bacterial infection, such as flu and roseola. Post –Immunization Seizures :-The risk of febrile seizure may increased due to some childhood immunization,such as Diphtheria,Tetanus and Pertussis vaccinations. Family History :-Some children inherit a family’s tendency to have seizures with a fever. 4
  5. 5. Treatment 5 Patients with active seizures should be treated with airway management. Anti-pyretic drugs (Acetaminophen, Ibuprofen) are used in febrile seizure by given oral or rectal route (when fever is started). Anti-convulsant agents (Diazepam, Lorazepam) after these drugs record child heart rate, blood pressure and breathing. Sometimes by sponging with room temperature water (not cold).
  6. 6. Aim & Objectives 6 Review the risk factor of febrile seizures. To know about the method to Improve Patient care. To Determine the Sign and Symptoms
  7. 7. Literature review 7 S.NO Author Article YEAR 1 Nooruddin R Tejani Febrile Seizures 2017 2 Syndi Seinfeld and John M. Pellock Recent Research on Febrile Seizures 2014 3 Tonia Jones and Steven j. Jacobsen Childhood Febrile Seizures 2007 4 Harvey, Eric, Adam and Thomas Treatment of Pediatric Neurological Disorders 2005 5 C Waruiru, R Appleton Febrile Seizures 2004 6 Anne, T Berg,Shlomo Shinnar Allen Hauser A Prospective Study Of Recurrent Febrile Seizures 1992
  8. 8. Literature review 8 S.NO Author Article YEAR 1 Janet L. Patterson Febrile Seizures 2013 2 Siba Prosad Paul Management of Febrile Convulsion In Children 2015 3 P.D Singhi, K. jayshree Febrile Seizures An Update 1995 4 Jithangi Wanigasinghe Management Of Simple Febrile Seizures 2017 5 Abdulafeez M.Khair and Dala Elmagrabi Febrile Seizures And Febrile seizures Syndromes: An Updated Overview Of Old And Current Knowledge 2015
  9. 9. To find out relevant articles Review of articles Compilation of information from different articles Compilation of thesis 9 Plan Of Work
  10. 10. Febrile seizures are the most common type of childhood seizures. The peak age of onset febrile seizures are 18 months. With temperature more than 38°C. Signs and symptoms include , loss of consciousness, Jerking of arm and legs, difficulty breathing, foaming at the month, Management involve symptom control and treating the cause of the fever. Febrile seizures do not cause neurological damage. Complex FS particularly if prolonged and an abnormal neurological status are recognised risk factor for the development of later epilepsy. It is important to realize some special febrile seizures syndromes ,which can have some long-term neurological abnormalities. 10 Conclusion
  11. 11. The risk of febrile seizures increased after certain combination of vaccines. Like, pneumococcal conjugate vaccine (PCV), trivalent inactivated influenza vaccine and diphtheria-tetanus-acellular-pertussis (DTaP). But the absolute risk of febrile seizures after these combination is less. 11 Conclusion
  12. 12. Syndi Seinfeld ,John M. Pellock; Recent research on febrile Seizures; J Neurol Neurophysiol 2014; 4(165):1-13. Tonia Jones, Steven J. Jacobsen; Childhood febrile seizure;. Int. J. Med. Sci.; 2007; 4:111-112. Nooruddin R Tejani; Febrile Seizures; medscape; 2017. Harvey, Eric, Adam,Thomas; Treatment of Pediatric Neurological Disorders; Taylor & Francis Group; 2005; 73-79. C Waruiru, R Appleton; Febrile Seizures; Arch Dis Child 2004; 89:751–756; doi: 10.1136/adc.2003.028449 Anne, T Berg,Shlomo Shinnar, Allen Hauser et al; A Prospective Study Of Recurrent Febrile Seizure; .The New England Journal of Medicine ; 1992; 327; 1122-1127. Patterson Janet.L. , A. Stephanie, Carapetian, et al;. Febrile Seizures;. Pediatric Annals. 2013; 45(12):258-263. 12 References
  13. 13. M.K. Abdulhafeez and E. Dalal. Febrile Seizures and Febrile Seizure Syndromes: An Updated Overview of Old and Current Knowledge,” Neurology Research International, vol.2015, no.7, pp.7, 2015. S.P. Paul, .Management Of Febrile Convulsion In Children.Journals.rcni, vol.23, number 2, pp. 1,2015. Singhi P.D, Jayshree K. Febrile seizures: An update. Indian Pediatrics. 1995; 32:565-572. Duffy Jonathan, Weintraub Eric, Simon, et al. Febrile seizures risk after vaccination in children 6 to 23 months. Pediatrics.2016;138(1):e20160320. 13 References
  14. 14. Thank you !!!.... 14
  • PankajMaurya51

    Sep. 24, 2018

Introduction Types of febrile seizures Causes Of Febrile Seizures Treatment Aim & Objectives

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