Choosing the appropriate research topic. satya pptx


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a starter to enter into medical research....a lazy professor"s workout....!!

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Choosing the appropriate research topic. satya pptx

  1. 1. *
  2. 2. *Development of scientific attitude - Evidence based medicine*Learning research methodology*Curricular requirement*publication *
  3. 3. *
  4. 4. *It Is a systematic and organised scientific process*To find answers to questions
  5. 5. * Research is to see what everybody else has seen, and to think what nobody else has thought………. ----Albert Szent-Gyorgyi
  6. 6. *is an important and complex part of the research process*You will need to do some research and reading *
  7. 7. CHOOSING THE APPROPRIATERESEARCH TOPIC Dr. V. Sathyanarayanan M.D., Professor of Pharmacology
  8. 8. *To know the processes involved in choosing the appropriate research topic*To formulate a research question ( aim and objectives )*To assess the quality of the research question effectively*To formulate a hypothesis for testing the research question *OBJECTIVES
  9. 9. *First and foremost, it must be interesting*You should learn something of value to you*It should be productive *
  10. 10. * Choose a mentor or guide
  11. 11. and then…1. Develop a research question * Do a thorough search of medical literature * Identify the edge of knowledge related to that question and gaps in knowledge * Be certain that your question has not already been answered AND that filling the gaps is important2. Develop a testable hypothesis *
  12. 12. *The man with a new idea is a crank until the idea succeeds….. *
  13. 13. *Not necessarily Archemedes or edison
  14. 14. *as you go about your daily clinical practice* observe with curiosity and enquire…..* Sometimes it is the result of having a disagree ment with a colleague*Define the problem well *
  15. 15. *Etiology and *Elucidate mechanisms pathogenesis*Pathophysiology*Diagnosis *Diagnostic approaches *Therapeutic*Treatment interventions*prognosis *Research into the prognostic factors *
  16. 16. *Consider personal interests*Engage in conversations with the mentor, colleagues, teachers and experts*Read articles*Browse recent issues of journals or magazines*Browse the shelves for books on your subject*Identify the research question area*Aware of overuse of ideas
  17. 17. *Concluding sections in the critically examined individual studies, systematic review*Remaining gaps in literature*Further define the research question*MEDLINE, PUBMED, SCIENCEDIRECT,* MEDSCAPE *
  18. 18. *From standard text books*Use article databases to scan current magazine, journal or newspaper articles on the topic* Use Web search engines to find Web sites on the topic *
  19. 19. *Keep it manageable.*Be aware if a topic is very recent*discuss your topic with your guide *
  20. 20. * Look for words that best describe your topic*Find synonyms, broader and narrower terms for each keyword you find*Keep a list of these words to use later as you search *
  21. 21. * it is common to modify your topic during the research process* Be aware of the depth of coverage needed and the due date.*Your guide will probably provide specific requirements *
  22. 22. *You will often begin with a word,*develop a more focused interest in an aspect of something relating to that word,* then begin to have questions about the topic.*Significance of the research question must be identified *
  23. 23. *Use the key words you have gathered to research in the* catalog, article databases* and Internet search engines.* Find more information to help answer your research question. *
  24. 24. * To steal from one is steal from many is research… ---Steven Right
  25. 25. * This may be the answer to your research question* and/or a way to clearly state the purpose of your research.* Your thesis statement will usually be one or two sentences* that states precisely what is to be answered, proven, or what you will inform your audience about your topic. *
  26. 26. * Trying to turn a statement into a real question *
  27. 27. *Possibly the most difficult part* is to come up with a reasonable question*and focus it to the point*where it can be answered*
  28. 28. * defining the goal of your research, * identifying objectives, * refining and refining it some more and * refining it even more until * you have a neat and simple question * that is feasible to answer.*
  29. 29. * stated in broad terms * and covers the topic that interests you*
  30. 30. * more focused* There could be more than one*but all would contribute to the overall goal*Define it*
  31. 31. * one of the on going topics in recent years is* whether medical marijuana has any place in the mains tream medical world.* The goal of research in this area would be*to assess whether medical marijuana is a useful treatment *
  32. 32. *What is the population I want to study?*How do I describe it – age, sex, background?*What is the intervention I want to study?*Do I have all the details of the intervention?*What is the outcome I want to achieve?*How am I going to measure the outcome? *
  33. 33. *PICO*P ‐ Population*I ‐ Intervention*C ‐ Comparison*O – Outcome Measured*
  34. 34. *Population ‐ children with cerebral palsy* Described ‐ ages 6 to 16*Intervention ‐ Medical marijuana* Details of intervention – dose and given orally*Outcome – frequency of spasm by 50%* Measure of outcome – Tic spasm score. *
  35. 35. *Medical marijuana, given orally X mg q.i.d will*reduce the frequency of spasms by 50%, as me asured by the Tic spasm score, in children with*cerebral palsy between the ages of 6 and 16 ye ars. *
  36. 36. * single statement that contains sufficient information that it can be tested using*statistical methodology
  37. 37. * are procedures for making rational decisions about*what is real and what is opinion *
  38. 38. *F – Feasible*I – Interesting*N – Novel*E – Ethical*R ‐ Relevant *
  39. 39. *Number of subjects*Alter inclusion and exclusion criteria*Equipment*cost *
  40. 40. *To you*To the guide*To the peers*Editors of the journals*Reviewers *
  41. 41. *Newer topic or idea*Not duplicated*Duplicated Will have a lower rating *
  42. 42. * Should follow existing guidelines like* ICMR code of Ethics in biomedical research* Clinical trials should follow  Good Clinical Practice Guidelines published by Government of India* Get the IEC approval *
  43. 43. *Addresses certain community needs*Addresses issues that will have an impact for policy making *
  44. 44. Questions to ask yourself Yes No Vague Is the question asked in a single sentence? Is the question simple?P Does the question specify the population?I Does the question state the intervention?C Is there a comparison group?O Is there a clear outcome in the question?O Has the measure for the outcome been specified?F Is the question FEASIBLE?I Is it INTERESTING ? to you? to others?N Is it NOVEL? ‐‐ new? Innovative?E ETHICAL? ‐‐ is there a state of equipoise between comp eting therapies? Will your investigations  harm?R RELEVANT? To policy makers? To patients?
  45. 45. * What is the sample size you are looking for ?* would you have access to the population you wanted?* Would the selected population agree to participate?* Would you be able to obtain the drug samples?* Think through what budget you might need?* Will the ethics committee approve of your project?* How novel are the questions? ( not repeated ) *
  46. 46. * Generating a good research question is an iterative process* that requires you to develop new conceptual schemes for the problem* the generation of “Concept Maps” a very usefultechnique for keeping our thinking straight* MindManager (* Inspiration ( *
  47. 47. * you can write the one page description required for the assi gnment.* should write the goal of the research,* what the general objective of the research is,* try to formulate specific aims which can be your refined que stion(s) and then,* if you have a hypothesis that can be tested, write that down.* summarize your thinking on the feasibility* and general plans you have for conducting the research. *
  48. 48. * Hulley SB, Cummings SR. “Designing Clinical Research: An epidemiological approach.* Centre for Health Evidence: “Users’ Guides to Evidence Based Practice”** Guidelines for graduate students: “Choosing and refining a research topic”* How to write Specific Aims:‐4.asp *
  49. 49. Even thousands of miles of journeystarts with a single step…….. lao tzu a chinese mystic