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Gastrointestinal disorders

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Immense research on Gastrointestinal disorders is seen due to its prevalence in majority countries in the world. thus its essential to understand how to tackle with it through natural medicine to avoid side effects of alopathy

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Gastrointestinal disorders

  1. 1. Plants that cure Gastro Intestinal disorders (GID – Part I) Presented by Dr. Sudhakar Kokate Director PPRC, India
  2. 2. Gastro-intestinal disorders (GID) Include : Colitis Constipation Diarrhoea Duodenal ulcers Dyspepsia Hyper-acidity PPRC/INDIA 01
  3. 3. In India  Plant species: 9500  Medicinal: 7500  Tribal medicinal plants: 300  For G.I. Disorders: Bael Isabgol Pale catechu Palas Shatavari Mandar Kurchi Ginger Carrot PPRC/INDIA 02
  4. 4. Around the World      Mexico: 65 plants to treat G.I. disorders (GID) Thailand: 38 plants for GID Germany / France: Many herbs used as prescription drug (Sale > $ 50 bn……2010) USA: $ 4 bn……1996 India: Drug market $1bn export of plant crude drugs $ 80 mn PPRC/INDIA 03
  5. 5. Knowledge of Medi-plants  Dates back to 400 B.C.  First documented in Atharva Veda dates back to 4500-1500 B.C.  119 compounds with therapeutic value have been identified till date  Japanese pharmacopoeia 1993 contains 123 active plants of which 29 are used in Western medicine PPRC/INDIA 04
  6. 6. Aconitum heterophyllum PPRC/INDIA 05
  7. 7. Aconitum heterophyllum  Habitat: Eastern Asia, Western Himalaya  Chemicals: - Astisine - Hetratisine - Histsine - Benzoyl-heterophyllum  It is employed in as a bitter tonic and anti-periodic PPRC/INDIA 06
  8. 8. Aegle marmelos PPRC/INDIA 07
  9. 9. Aegle marmelos  Habitat: India, China, Sri Lanka, Burma, Thailand  Chemicals: Leaves: Alkaloid, Agelin, Sterol as Vsitosterol and Coumarins, Essential oils such as d-limonene Bark: Aegelinin, Marmin PPRC/INDIA 08
  10. 10. Aegle marmelos  Chemicals: Fruit: Sugar, Tannin Pulp: 2 furocoumarins-psoraen and Marmelosin  1/22/2014 Properties: Astringent, Depurative, Alexeteric, Cooling, Anti-poison PPRC/INDIA 09
  11. 11. Amphipterygium adstringens PPRC/INDIA 10
  12. 12. Amphipterygium adstringens Most gastro-protective compounds:  3 epi-oleanolic acid  3 alpha-hydroxy mastica dienonic acid  Beta-sitosterol acid PPRC/INDIA 11
  13. 13. Arnica montana PPRC/INDIA 12
  14. 14. Arnica montana  The plant is rich in Sesquiterpenes  It has advantage in states of depression, diarrhoea, dysentery, pneumonia, typhoid and excessive sweating PPRC/INDIA 13
  15. 15. Asparagus adscendens PPRC/INDIA 14
  16. 16. Asparagus adscendens  Habitat: India – forests of Uttar Pradesh, East Asia, Afghanistan, Himalayas, Iran  Chemical: Asparagine  Roots: Demulcent, Diaphoretic, Galactogogue, Stimulant are useful in the treatment of Diarrhoea and dysentery PPRC/INDIA 15
  17. 17. Calotropis gigantea PPRC/INDIA 16
  18. 18. Calotropis gigantea  Habitat: Sub-tropic & Tropic, India, Sri Lanka, West Indies  Active principles: Saponins, Glucoside, Tannins, Lugeol, Flavonoids, Glycine, Butrin, Isobutrin, 3-o acetyl-calotropin  Root Bark extensively used for GID PPRC/INDIA 17
  19. 19. Coriandrum sativum PPRC/INDIA 18
  20. 20. Coriandrum sativum  Coriander seed oil has anti-bacterial property and is used for treating colic, neuralgia, rheumatism, diarrhoea, hemorrhoids, flatulence and abdominal pains PPRC/INDIA 19
  21. 21. Curcuma longa PPRC/INDIA 20
  22. 22. Curcuma longa  Active principle: Curcumin diferuoylemethane PPRC/INDIA 21
  23. 23. Daucus carota PPRC/INDIA 22
  24. 24. Daucus carota  Chemicals: Lutenolin-7-glucoside, Mevolonic acid, Pyrolidine daucine & Essential oils  Used in stomach & intestinal problems  Carrot soup remedy for diarrhoea  Properties: Anthelmintic, Carminative, Diuretic and Stimulant PPRC/INDIA 23
  25. 25. Eugenia jambolana PPRC/INDIA 24
  26. 26. Eugenia jambolana  Seed powder effective in diarrhoea, dysentery and diabetes  Habitat: India, Queensland  Chemicals: Oleanolic acid, Glucoside showed significant reduction & G.I. motility  Fruit: Astringent, Stomachic, Carminative, Diuretic, Spleen enlargement, Chronic diarrhoea & Urine retention PPRC/INDIA 25
  27. 27. Helicteres isora PPRC/INDIA 26
  28. 28. Helicteres isora  Chemicals: - Phytosterol - Hydroxy-carboxylic acid - Phytolobotannins  Effective against G.I. disorders PPRC/INDIA 27
  29. 29. Melissa officinalis PPRC/INDIA 28
  30. 30. Melissa officinalis  In Germany, Lemon balm is used as a medicinal tea to treat G.I. disorders  Chemicals: 0.05% Volatile oil, Rosemary acid PPRC/INDIA 29
  31. 31. Ocimum sanctum PPRC/INDIA 30
  32. 32. Ocimum sanctum  Phyto-chemicals: Essential oils, Eugenol, Methyl ether, Terbinene-4-01, Spigennins, Apigenin-7-0-glucuronide  Pharmacological action: Hypotensive activity, Inhibition of smooth muscle contraction induced by Acetylcholine, Carbachol and Histamine PPRC/INDIA 31
  33. 33. Pueraria lobata PPRC/INDIA 32
  34. 34. Puerata lobata  In China, Japan; leaves, roots and shoots are used for treating Alcoholism, Cold flu, G.I. disorders  Flowers and tubers are used for treating Fever, Cold, Diarrhoea, Dysentery and Acute intestinal ailments PPRC/INDIA 33
  35. 35. Phyto-drugs* for curing G.I. Disorders Drugs/Chemical Aesculetin Plant used Frazinus rhychophylla Andrographolide Andrographis paniculata Berberine Berberis vulgaris Hemsleyadin Hemsleya amabilis Neoandrographolide Andrographis paniculata * Commercial PPRC/INDIA 34
  36. 36. Thank You !!

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