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Rheumatic Fever
IntroductionRheumatic fever is aninflammatory disease thatoccurs following aStreptococcus pyogenesinfection, such asstrept...
Rheumatic heart diseaseChronic rheumatic heartdisease (RHD) ischaracterized by repeatedinflammation with fibrinousresoluti...
TreatmentThe management of acuterheumatic fever is gearedtoward the reduction ofinflammation with anti-inflammatory medica...
EpidemiologyRheumatic fever is commonworldwide and responsiblefor many cases of damagedheart valves. Rheumaticfever primar...
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Rheumatic Fever

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Rheumatic fever may cause a temporary nervous system disorder. Nowadays it’s known as chorea, or Sydenham’s chorea. This is often a nervous disorder by rapid, jerky, involuntary movements of the body occurring primarily in childhood or during pregnancy and is closely related to rheumatic fever.

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Rheumatic Fever

  1. 1. Rheumatic Fever
  2. 2. IntroductionRheumatic fever is aninflammatory disease thatoccurs following aStreptococcus pyogenesinfection, such asstreptococcal pharyngitisor scarlet fever. Believedto be caused by antibodycross-reactivity that caninvolve the heart, joints,skin, and brain.
  3. 3. Rheumatic heart diseaseChronic rheumatic heartdisease (RHD) ischaracterized by repeatedinflammation with fibrinousresolution. The cardinalanatomic changes of thevalve include leafletthickening, commissuralfusion, and shortening andthickening of the tendinouscords.It is caused by anautoimmune reaction toGroup A β-hemolyticstreptococci (GAS) thatresults in valvular damage.
  4. 4. TreatmentThe management of acuterheumatic fever is gearedtoward the reduction ofinflammation with anti-inflammatory medicationssuch as aspirin orcorticosteroids. Individualswith positive cultures forstrep throat should also betreated with antibiotics.Aspirin is the drug of choiceand should be given at highdoses.
  5. 5. EpidemiologyRheumatic fever is commonworldwide and responsiblefor many cases of damagedheart valves. Rheumaticfever primarily affectschildren between ages 5and 17 years and occursapproximately 20 days afterstrep throat. In up to a thirdof cases, the underlyingstrep infection may nothave caused any symptoms.

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