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EAROMICS
H2O = Humanization of Healthcare
Prof.Dr.O.Ferrer-Roca, 2015
Prof.Dr.O.Ferrer-Roca, 2015
PULSEOXIMETRY
The noninvasive measurement of arterial oxygen saturation
(SpO2) by pulse oximetry has become a standard of ...
ABP versus PPG
• Utility of the Photoplethysmogram in Circulatory
Monitoring
• Anesthesiology. 2008;108(5):950-958.
doi:10...
Digital Pulse Analysis (DPA) is the next evolution in pulse
wave velocity (PWV), and is based on the measurement
of reflec...
Clasical Pulseoxymeter
Prof.Dr.O.Ferrer-Roca, 2015
PPG analysis. I.- FFT (frequency domain)
Frequencies of the Autonomic Nervous System:
1.-VLF (very low frequency) 0.0033-0...
PPG analysis. II.-Time domain
Prof.Dr.O.Ferrer-Roca, 2015
HRV = Heart rate variability
valuable indicator of phrophylactic cardiovascular interventions
SD1= Short term beat-to-beat...
Healthy CV patients have a well defined “dicrotic wave” in the
diastolic phase at D, whereas 98% of overt arteriosclerotic...
Second peak value
Prof.Dr.O.Ferrer-Roca, 2015
Second derivative APG wave
Prof.Dr.O.Ferrer-Roca, 2015
Second
derivative
APG wave
Prof.Dr.O.Ferrer-Roca, 2015
Differences of sensitivity
Prof.Dr.O.Ferrer-Roca, 2015
Respiratory frequency
Prof.Dr.O.Ferrer-Roca, 2015
LVED= LeftVentricular End Diastolic Pressure
Capable to indicate and grade CHF = Chronic Heart Failure
Prof.Dr.O.Ferrer-Ro...
Comprensive measuring
Prof.Dr.O.Ferrer-Roca, 2015
Compressive reporting
Prof.Dr.O.Ferrer-Roca, 2015
Report
Prof.Dr.O.Ferrer-Roca, 2015
Now everything is available 24h/day
• H2O = Humanization of Healthcare
• EAROMICS with PPG from the ear
• Costumized and h...
Extended to GSR & EDA
GSR= Galvanic Skin Response
EDA= Electrodermal Activity
Prof.Dr.O.Ferrer-Roca, 2015
Extended to EEG
Prof.Dr.O.Ferrer-Roca, 2015
Extended to eating habits
Prof.Dr.O.Ferrer-Roca, 2015
Extended to Glucosae
NIR glucometer by Arduino
InGaAs photodiode, 8 LEDs(2 x Green, 2 x NIR @ 1550nm, 1 IR @ 960nm, 1 Red)...
4P (preventive-pervasive-proactive-personalized)
DIY data  HSD (health small data)
Prof.Dr.O.Ferrer-Roca, 2015
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EAROMICS -2015

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Health data capture with IoT located on the external ear.
http://www.scoop.it/t/health-4-0

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EAROMICS -2015

  1. 1. EAROMICS H2O = Humanization of Healthcare Prof.Dr.O.Ferrer-Roca, 2015 Prof.Dr.O.Ferrer-Roca, 2015
  2. 2. PULSEOXIMETRY The noninvasive measurement of arterial oxygen saturation (SpO2) by pulse oximetry has become a standard of care. In addition to oxygen saturation values, many pulse oximeters display a photoelectric plethysmographic waveform, which reflects a combination of volume and flow changes in skin microcirculation. Plethysmographic wave displayed is highly processed and filtered signal (Inverted, autocentered, autogained, and after a bandpass filtering. Prof.Dr.O.Ferrer-Roca, 2015
  3. 3. ABP versus PPG • Utility of the Photoplethysmogram in Circulatory Monitoring • Anesthesiology. 2008;108(5):950-958. doi:10.1097/ALN.0b013e31816c89e1 Photoplethysmography Arterial blood pressure Prof.Dr.O.Ferrer-Roca, 2015
  4. 4. Digital Pulse Analysis (DPA) is the next evolution in pulse wave velocity (PWV), and is based on the measurement of reflected infrared light (IR). At a frequency of 805 nm, both oxygenated and deoxygenated blood have the same absorption, thereby ensuring accuracy based on blood flow alone. In fact only IR signal at 940 nm is presented in the PPGs because It is much more stable in time if compared with the Red signal at 660 nm that is more susceptible of changes in oxygen saturation. PI (perfussion index) = (AC pulsating IR signal/ AD non-pulsating IR signal ) x 100 % AC= Alternate curve component DC= Direct curve component (venous movement = right atrial contraction + ventilation )Prof.Dr.O.Ferrer-Roca, 2015
  5. 5. Clasical Pulseoxymeter Prof.Dr.O.Ferrer-Roca, 2015
  6. 6. PPG analysis. I.- FFT (frequency domain) Frequencies of the Autonomic Nervous System: 1.-VLF (very low frequency) 0.0033-0.04 Hz 2.- LF (low frequency) Mayer waves 0.04-0.15 Hz 3.- HF (high frequency)Vagus Nerve 0.15-0.4 Hz Sympathetic predominance LF norm = LF/LF+HF Parasympathetic predominance HF norm = HF/ LF+HF Prof.Dr.O.Ferrer-Roca, 2015
  7. 7. PPG analysis. II.-Time domain Prof.Dr.O.Ferrer-Roca, 2015
  8. 8. HRV = Heart rate variability valuable indicator of phrophylactic cardiovascular interventions SD1= Short term beat-to-beat variability SD2= Long term beat-to-beat variability x= HHI or RRI sequences Var= variance of sequences SDNN= SD of HHI or RRI Selvaraj, N.; Jaryal,A.; Santhosh, J.; Deepak, K.K.; Anand, S. Assessment of heart rate variability derived from finger-tip photoplethysmography as compared to electrocardiography.J. Med. Eng.Tech. 2008, 32, 479-484. PRV= Pulse rate variability now is used from PPG Prof.Dr.O.Ferrer-Roca, 2015
  9. 9. Healthy CV patients have a well defined “dicrotic wave” in the diastolic phase at D, whereas 98% of overt arteriosclerotic patients had significant decrease or disappearance of the wave Elements of PTG (Systolic Phase) 1. S (Starting Point) Starting point of systolic phase of arterial pulse-wave. Aortic valve opens and the blood of the LV is ejected into aorta. 2. P (PercussionWave) Wave caused from LV ejection that increases the blood volume within artery. Higher point means stronger LV ejection and higher compliance of larger artery. 3.T (TidalWave) Reflected wave from the small artery. Higher point means contraction and stiffness of small artery. 4. C (Incisura) End-point of systolic phase, then aortic valve is closed. Less drop from pulse height (PH) means larger resistance (arterial contraction & tension). Prof.Dr.O.Ferrer-Roca, 2015
  10. 10. Second peak value Prof.Dr.O.Ferrer-Roca, 2015
  11. 11. Second derivative APG wave Prof.Dr.O.Ferrer-Roca, 2015
  12. 12. Second derivative APG wave Prof.Dr.O.Ferrer-Roca, 2015
  13. 13. Differences of sensitivity Prof.Dr.O.Ferrer-Roca, 2015
  14. 14. Respiratory frequency Prof.Dr.O.Ferrer-Roca, 2015
  15. 15. LVED= LeftVentricular End Diastolic Pressure Capable to indicate and grade CHF = Chronic Heart Failure Prof.Dr.O.Ferrer-Roca, 2015
  16. 16. Comprensive measuring Prof.Dr.O.Ferrer-Roca, 2015
  17. 17. Compressive reporting Prof.Dr.O.Ferrer-Roca, 2015
  18. 18. Report Prof.Dr.O.Ferrer-Roca, 2015
  19. 19. Now everything is available 24h/day • H2O = Humanization of Healthcare • EAROMICS with PPG from the ear • Costumized and hack4health Oxirate ® Flip ® Ear-o-Smart ® Prof.Dr.O.Ferrer-Roca, 2015
  20. 20. Extended to GSR & EDA GSR= Galvanic Skin Response EDA= Electrodermal Activity Prof.Dr.O.Ferrer-Roca, 2015
  21. 21. Extended to EEG Prof.Dr.O.Ferrer-Roca, 2015
  22. 22. Extended to eating habits Prof.Dr.O.Ferrer-Roca, 2015
  23. 23. Extended to Glucosae NIR glucometer by Arduino InGaAs photodiode, 8 LEDs(2 x Green, 2 x NIR @ 1550nm, 1 IR @ 960nm, 1 Red) an Atmega328p, and the circuits required to run those. Also it contains a small LiPo in order to be able to test, or take training data.Two separate circuit boards and the ADC is channeled through an MCP3421 and then i2c goes across a connector at the bottom which also supplies the regulated 3.3V Prof.Dr.O.Ferrer-Roca, 2015
  24. 24. 4P (preventive-pervasive-proactive-personalized) DIY data  HSD (health small data) Prof.Dr.O.Ferrer-Roca, 2015

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