On 23 and 30 November 2020, the OECD hosted a webinar on training needs, resources, and opportunities for adverse outcomes pathways (AOPs). This interactive webinar discussed opportunities for expanding the AOP community of trainers to meet current needs, considering all available resources. The objectives of this webinar were to: - outline past and current training activities - receive your input on experiences in conducting and/or receiving training; and - gather your views, needs and ideas for the provision of training in the future Watch the webinar video recording at: https://youtu.be/7ObxATifDds.

1. Zoom Instructions
Q&A function: During the presentation you may have a question that you’d like to be
answered.
Please send your questions at any time during the talk via the Q&A function in the Zoom control
panel so it does not get lost in the Chat Room chatter.
We will respond to as many questions as possible during the Q&A sessions.
This webinar will be recorded and will be made available afterwards at: oe.cd/testing-
webinars
Assistance In case of technical problems write to Carole.GUERRIER@oecd.org or Hannah.THABET@oecd.org

2. Webinar on:
TRAINING IN AOPs: NEEDS, RESOURCES AND
OPPORTUNITIES
Monday 30 November 2020
10AM CET / 6PM JST

3. Role concerning AOPs*:
o develop AOP framework
o coordinate development and review
o build an AOP knowledge base
o support regulatory programmes
o promote international uptake
OECD AOP Development Programme
EAGMST meeting OECD, Paris.
Extended Advisory Group on Molecular Screening
and Toxicogenomics (EAGMST)
*since taking responsibility in 2012

4. HGGIR
Handbook,
guidance, AOP-
wiki
‘gardening’,
internal review
AOP-KB
EAGMST Subgroups
ETO
Education,
training, outreach
AOP external
reviews and
publications
Continuous recruitment of members

5. • develop, undertake and maintain activities related to:
– training,
– education and
– further dissemination of knowledge about the AOP framework
• promote the application of AOP knowledge in support of
wider use of New Approach Methodologies (NAMs)
OECD EAGMST subgroup on Education,
Training & Outreach (ETO)

6. Presenters
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Enter photo
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Bette MeekKristie SullivanMirjam Luijten
University of Ottawa
Canada
Physicians Committee for
Responsible Medicine
National Institute for Public
Health and the Environment, NL
Brigitte Landesmann
Joint Research Centre
European Commission

7. INTRODUCTION
Mirjam Luijten
National Institute for Public Health and the Environment (RIVM)
Mirjam.Luijten@rivm.nl

8. Adverse Outcome Pathways:
• Have been adopted as useful tool for organizing biological and
toxicological knowledge
• However, training courses in AOPs have been:
– limited in scope (e.g. domains, purpose)
– incomplete
➔ there is a clear need for consistency and expansion
• AOP Trainers
– limited in number and geographical distribution
– lack of structural exchange of experiences, messaging, materials, needs etc.
Why this webinar?

9. • Subgroup on AOP Education, Training & Outreach (ETO)
Who are we?
OECD Extended Advisory Group on Molecular Screening &
Toxicogenomics

10. Improvement/expansion of training in AOPs:
1. To collect your input
– needs, gaps and ideas
2. To establish a community of trainers
– to exchange experiences and materials for training
3. To identify ‘AOP champions’ to strengthen outreach
– to promote development and application of AOPs
4. To collect your feedback
Webinar objectives

12. Agenda
• Introduction to the webinar aims
• Getting to know you
• From data to knowledge and beyond: AOPs as common interface
• Your experiences and views
• Our vision for AOP training
• Closing and next steps

13. Go to: www.Slido.com
Event code: #AOPTraining