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@DocNikko
OFDT 2013
Pas QUE les Jeunes !
OFDT 2017
Milieu festif / alternatif / techno : jeunes adultes
Milieu homosexuel : espace festif et parties sexuelles
Anciens dépendants aux (drogues) psychostimulants
Usagers occasionnels de drogues, socialement insérés
E-trip reports : partage d’expériences
First cathinone
First synthetic
cannabinoid
50 cathinones
112 cannabinoids
European Drug Report 2014European Drug Report 2014
Henderson GL. J Forensic Sci 1998
Kath
CaThiNones
Prosser et al. J Med Toxicol, 2012
Prosser et al. J Med Toxicol, 2012
Prosser et al. J Med Toxicol, 2012
Spiller HA. Clin Tox 2011
DAT/SERT ratio
5-HT
Dominant
DA
Dominant
Effets dopaminergiques
Effets sérotoninergiques
Effets cocaïne-like
Effets methamphétamine-like
Cameron. Br J Pharmacol, 2013
Kloss&Bruce
4-MEC (4-Methylethcathinone)
Crystal Bath
Kratom 2-MPA (2-Methiopropamine)
MTX
(Methoxetamine)
MXE
Syndrome sérotoninergique
NEJM 2005
Kloss&Bruce
5F-AMB
AM2201 analogue
AB-CHIMINACA
5F-AMBICA
MEPIRAPIM
PP22 analogue
FUBIMINFA
ADBPINACA
2014
with new molecules
JohnW.Huffman(ClemsonUniv.1980)
NEJM 2017
… Original manufacturing procedure
Cannabinoid
Hyperemesis
Syndrome
Habboushe J. Am J Emerg Med 2014
CHS
Jeux
Dangereux ?
OFDT 2013
BKL. NYC
JUL. 2016
Zombie
Outbreak
The new engl and jour nal o f medicine
From the Clinical Toxicology and Environ-
mental Biomonitoring Laboratory (A.J.A.,
R.G.) and School of Medicine (A.J.A.),
University of California, San Francisco,
San Francisco, and the Department of
BACKGROUND
New psychoactive substances constitute a growing and dynamic class of abused
drugs in the United States. On July 12, 2016, a synthetic cannabinoid caused mass
intoxication of 33 persons in one New York City neighborhood, in an event de-
scribed in the popular press as a “zombie” outbreak because of the appearance of
ABSTR ACT
“Zombie” Outbreak Caused by the Synthetic
Cannabinoid AMB-FUBINACA in New York
Axel J. Adams, B.S., Samuel D. Banister, Ph.D., Lisandro Irizarry, M.D.,
Jordan Trecki, Ph.D., Michael Schwartz, M.D., M.P.H., and Roy Gerona, Ph.D.
Original Article
@DocNikko

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