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Turning up the volume on a silent killer: Pancreatic Cancer


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Shannon Nelson is a PhD student at NICB and her project focuses on analysing the genetic basis of Pancreatic Cancer.

Shannon recently produced this slidedeck to explain her research for the 2018 DCU "Tell It Straight" competition.

"Tell it Straight" is an annual DCU-run science communication competition that challenges post-graduate PhD students to communicate their research to a general audience and panel of judges that have no prior knowledge of their research, using either a presentation or a video.
The competition was held on March 7th 2018 in HG22, Nursing Bldg., DCU.

Published in: Health & Medicine
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Turning up the volume on a silent killer: Pancreatic Cancer

  1. 1. Turning Up The Volume On A Silent Killer - The Study Of The Genetic Basis Of Pancreatic Cancer Shannon Nelson 2nd Year PhD Student NICB
  2. 2. Pancreatic Cancer • The Pancreas • Produces enzymes • Produces hormones • Pancreatic Cancer • 540 diagnosed in Ireland each year • 5 year survival rate – 8% • Poor Survival Rate • Lack of symptoms • Poor response to therapies • No screening or tests
  3. 3. Projected Cancer Deaths Rahib et al, Cancer Research, 2014 Pancreas Lung Colorectal Breast Prostate 0 20 40 60 80 100 120 140 160 180 2010 2012 2014 2016 2018 2020 2022 2024 2026 2028 2030 ProjectedCancerDeaths(Thousands)
  4. 4. Pancreatic Cancer Patients Non-Patients
  5. 5. Pancreatic Cancer Patients Non-Patients
  6. 6. Growing Cancer Cells in the Lab Cancer Cells in 2D
  7. 7. Growing Cancer Cells in the Lab Cancer Cells in 3D
  8. 8. • Validation of biomarkers • Earlier detection of pancreatic cancer • 3D cancer model development • Personalised therapy of pancreatic cancer • Better treatment outcomes for pancreatic cancer patients How My Work Will Make a Difference
  9. 9. Acknowledgements • Dr Naomi Walsh • Dr AnneMarie Larkin • Dr Denis Collins • Dr Alex Eustace • Dr Laura Breen • Neil Conlon • Nicola Gaynor • Alacoque Browne • Prof John Crown