Radio on Fiber-Distributed Antenna System (RoF- DAS) is known to improve coverage and performance of wireless communications. Currently, various multiplexing schemes in RoF-DAS for transport Multiple Input Multiple Output (MIMO) signals in a ﬁber link are studied. The RoF-DAS over Wave- length Division Multiplexing - Passive Optical Network (WDM- PON) with optical Time Division Multiplexing (TDM) is actively researched. This system uses optical switcher to multiplex a set of MIMO radio signals in a ﬁber and transfer to the Remote Antenna Unit (RAU). Since a pair of switches multiplex and demultiplex MIMO radio signals, two switches are required to synchronize completely. Therefore, there is a problem that high performance switches are required to perform the clock extraction. This paper proposes asynchronous optical TDM. In this proposal, synchronization mismatch is compensated by estimating the amount of drifting and cancel it out at the RAU. The bit error ratio (BER) performance is evaluated by using computer simulation.