INHERITANCE OF SEX Heterochromosomes genes that determine sex, are in a pair of chromosomes being different in shape and size. Remain 22 pairs of chromosomes autosomes. Somatic cells: 44 autosomes + 2 sex chromosomes. FEMALE MALE 22 22 autosomes autosomes XX XY Any numerical aberration is considered a mutation disease. Klinefelter’s syndrome karyotype 47, XXY: male phenotype, femenine characteristics.
SEX-LINKED INHERITANCE RARE DISEASE Gene not determining a sex Low incidence in the characteristic located on X population. chromosome. Only affect less than 5 per Hemophilia and colour 10.000 inhabitants. blindness: X-linked. WHO: approximately 700 rare Y-linked women could not have diseases affecting 7% of the that allele. world population. Passed on from fathers to sons Spain: 3 million people with rare diseases.
FATTY ACIDS and MYELIN Long chains of hydrocarbons with a carboxyl terminal. Saturated fatty acids single bonds which in the carbon atoms surrounded by hydrogen atoms. Unsaturateddouble bonds. Monounsaturated single double bond. Polyunsaturated 2 or more double bonds present in a long chain fatty acid.Myelin Lipoprotein that covers the axon of neurons. Propagates the electrical impulses along neurons much faster. Demyelination: slows electrical condution decreasing normal functional activity.