Hyperemesis gravidarum


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Hyperemesis gravidarum

  1. 1. Jordan Iness Michael Giovine Holly Royer Elsa C
  2. 2. <ul><li>Hypermesis Education and Research. “Neurological Conditions: Wernicke’s Encephalopathy.” Updated Apr. 9, 2009. http://www.helpher.org/health-professionals/complications/neurological.php (Apr. 14, 2009). </li></ul><ul><li>Kantor, D. MedlinePlus. “Wernicke-Korsakoff Syndrome.” Updated Sept. 10, 2006. . http://www.nlm.nih.gov/medlineplus/ency/article/000771.htm (Apr. 14, 2009). </li></ul><ul><li>Nguyen-Khoa. “Beriberi (Thiamine Deficiency).” Updated May 20, 2008. http://emedicine.medscape.com/article/116930-overview (Apr. 14, 2009). </li></ul><ul><li>Ehrlich, Steven D. “Vitamin B1 (thiamine).” Updated Aug. 28, 2007. http://www.umm.edu/altmed/articles/vitamin-b1-000333.htm (Apr. 14, 2009). </li></ul><ul><li>Lord L. Management of Hyperemesis Gravidarum with Enteral Nutrition. Nutrition Issues in Gastroenterology, Series 63. June 2008. </li></ul><ul><li>Van Voorhees, Benjamin W. “Beriberi.” Updated July 21, 2006. http://healthguide.howstuffworks.com/beriberi-dictionary.htm (Apr. 14, 2009). </li></ul>
  3. 3. <ul><li>Velma is excited about her first pregnancy, and her expected delivery next month. Her family and </li></ul><ul><li>friends are impressed by the fact that she has been in good spirits, despite the fact that she has </li></ul><ul><li>suffered from an acute case of hyperemesis gravidarum for her entire pregnancy. However, they </li></ul><ul><li>report that she has recently begun to “make up elaborate stories” and appears to be drunk at times. </li></ul><ul><li>This information combined with her unexpected poor weight gain leads her clinician to be very </li></ul><ul><li>concerned about malnutrition, especially thiamine deficiency . Explain the connections. </li></ul>
  4. 4. <ul><li>Definition: Hyperemesis gravidarum (HG) is marked by continuous nausea and vomiting which can lead to dehydration, malnutrition and weight loss. </li></ul><ul><ul><li>The malnutrition is due to the fact that the woman is constantly throwing up and nutrients are not being absorbed </li></ul></ul>
  5. 5. <ul><li>It is an essential nutrient(B1): the body does not produce thiamine naturally so it must be consumed through diet. </li></ul><ul><li>It is water soluble and the body does not store it so it must be replaced everyday (excess thiamine is easily flushed out) </li></ul><ul><li>Coenzyme that helps the body obtain energy from food </li></ul><ul><li>It is required for the body to form ATP </li></ul>
  6. 6. <ul><li>One of the most significant factors of malnutrition in HG is thiamine deficiency. </li></ul><ul><li>Some of the symptoms of thiamine deficiency (beriberi): can cause a person to feel fatigued, weak and have resting tachycardia </li></ul><ul><ul><li>Dry beriberi: effects the nerves and muscles; memory loss and mental confusion, involuntary eye movements and trouble standing. </li></ul></ul>
  7. 7. <ul><li>Potential result of thiamine deficiency </li></ul><ul><li>Can develop after just a few weeks of vomiting. </li></ul><ul><li>In up to 20% of cases, it was found to be fatal and spontaneous abortion can occur. </li></ul><ul><li>Symptoms: visual disturbances, confusion and muscular weakness. </li></ul><ul><li>Can lead to Wernicke-Korsakoff (alcoholic encephalopathy): brain disorder resulting in the loss of specific brain functions and is the result of thiamine deficiency. </li></ul><ul><ul><li>Symptoms: double vision, eye movement abnormalities, loss of muscle coordination (unsteady walking), loss of memory, inability to form new memories, confabulation (making up stories) and hallucinations. </li></ul></ul>
  8. 8. <ul><li>Vitamin B injections into a vein or muscle </li></ul><ul><li>Take vitamin B1 supplements </li></ul><ul><li>Thiamine </li></ul>
  9. 9. <ul><li>Thiamine deficiency effects the central and peripheral nervous system- balance, coordination and cranial nerves that control eye movements </li></ul><ul><li>ATP is used as energy for muscle contraction </li></ul><ul><li>Thiamine deficiency decreases the production of ATP by disrupting the major pathway for glucose from the carbohydrates you take in. </li></ul>
  10. 10. <ul><li>Thiamine=money </li></ul><ul><li>Need money for gas for new car (pregnancy) </li></ul><ul><li>You lose your job (thiamine deficiency – due to vomiting) </li></ul><ul><li>Bills not paid (Wernicke’s Encephalopathy) </li></ul><ul><li>Potentially lose your car (death/spontaneous abortion) </li></ul><ul><li>Or get a job ( B1 vitamin supplements/injections) </li></ul>
  11. 11. <ul><li>http://images.google.com/imgres?imgurl=http://www.mdconsult.com/das/patient/body/0/0/10041/18098_en.jpg&imgrefurl=http://www.mdconsult.com/das/patient/body/0/0/10041/30098.html&usg=__PdgWD8exVZ7cMIeCjNa3HGTgpH8=&h=320&w=400&sz=23&hl=en&start=19&um=1&tbnid=d8-XN8-KpLuKyM:&tbnh=99&tbnw=124&prev=/images%3Fq%3Dthiamine%26ndsp%3D18%26hl%3Den%26sa%3DN%26start%3D18%26um%3D1 </li></ul>