The krebs cycle

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The krebs cycle

  1. 1. The Krebs Cycle <ul><li>Occurs in the matrix of the mitochondrion </li></ul><ul><li>Aerobic phase (requires oxygen) </li></ul><ul><li>2-carbon acetyl CoA joins with a 4-carbon compound to form a 6- carbon compound called Citric acid </li></ul>
  2. 2. <ul><li>Citric acid (6C) is gradually converted back to the 4-carbon compound </li></ul><ul><li>- ready to start the cycle once more </li></ul><ul><li>The carbons removed are released as CO 2 </li></ul><ul><li>-enzymes controlling this process called decarboxylases </li></ul><ul><li>The hydrogens, which are removed, join with NAD to form NADH2 </li></ul><ul><li>-enzymes controlling the release of hydrogen are called dehydrogenases </li></ul>
  3. 4. The Cytochrome System <ul><li>6 points along pathway where hydrogen is released and temporarily bound to NAD </li></ul><ul><li>Reduced coenzyme NADH 2 transfers hydrogen to a chain of hydrogen carriers called cytochrome system </li></ul><ul><li>These systems are attached to the cristate of every mitochondrion </li></ul>
  4. 5. <ul><li>Transfer of hydrogen from each NADH 2 along system </li></ul><ul><li>-produces 3 ATP </li></ul><ul><li>-process called oxidative phosphorylation </li></ul><ul><li>Complete oxidation of glucose yields 38 ATP </li></ul><ul><li>-2 during glycolysis </li></ul><ul><li>-36 during oxidative phosphorylation </li></ul>
  5. 7. The role of oxygen <ul><li>Final hydrogen acceptor </li></ul><ul><li>Combines to form water </li></ul><ul><li>Controlled by enzyme cytochrome oxidase </li></ul><ul><li>Presence of oxygen also essential for hydrogen to pass along the cytochrome system </li></ul>
  6. 8. This powerpoint was kindly donated to www.worldofteaching.com http://www.worldofteaching.com is home to over a thousand powerpoints submitted by teachers. This is a completely free site and requires no registration. Please visit and I hope it will help in your teaching.

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