Successfully reported this slideshow.
We use your LinkedIn profile and activity data to personalize ads and to show you more relevant ads. You can change your ad preferences anytime.
Progress and Hope:
A Historical Perspective
on the OM Field
Kenneth Hovland, MD
Ocular Melanoma Patient and Caregiver Symp...
50 years ago:
• Removal of the eye
was the only option
Positive attitude!
• Nationally, at the AFIP (1949-1970)
there was a 20% error in diagnosis !
Indirect ophthalmoscope
(1960’s)
Photography
Ultrasonography
(1970’s)
B-scan A-scan
Radiation
(1970’s)
• Large dose needed
Radioactive Iodine125 Proton beam
plaque
Collaborative Ocular
Melanoma Study
(COMS 1986-2003)
For Medium tumors (2.5 to 10 mm thick)
?any survival advantage with:
...
1500 patients in 40+ centers
Iodine-125 plaque vs.Enucleation
 Survival is equal
 Quality of life
issues
• Cobalt 60
• Iodine 125
• Palladium 103
• Ruthenium 106
• In patients with Large tumors (>10 mm thick)
(requiring enucleation anyway),
would pre-operative external radiation help...
COMS
• Now 40 additional centers in US and Canada
with expertise to diagnose and treat ocular
melanoma
• Accuracy: 99.7%
(...
Frequency of ocular melanoma
(5-6 per million)
• Unchanged for many decades,
• Compared with definite increase of
skin mel...
Optical Coherence Tomography
(OCT)
Magnetic Resonance Imaging
(MRI)
Positron Emission Tomography
(PET)
• Genetic aspects
Skin melanoma is different than ocular melanoma
Skin Eye
Team approach for patients:
• Ophthalmic oncologist
• Radiation oncologist, physicists
• Ultrasonographers
• Ophthalmic ph...
Basic research
• A lot of progress has been made in
the diagnosis and management of
ocular melanoma
Challenges
 Earlier detection
 Decrease side effects of radiation
 Better treatment for metastases
Thanks to Dr. Sara Selig, with her own personal
experience with ocular melanoma, for bringing
together such a range of per...
Progress and Hope: A Historical Perspective on the OM Field
Progress and Hope: A Historical Perspective on the OM Field
Progress and Hope: A Historical Perspective on the OM Field
Progress and Hope: A Historical Perspective on the OM Field
Progress and Hope: A Historical Perspective on the OM Field
Upcoming SlideShare
Loading in …5
×

of

Progress and Hope: A Historical Perspective on the OM Field Slide 1 Progress and Hope: A Historical Perspective on the OM Field Slide 2 Progress and Hope: A Historical Perspective on the OM Field Slide 3 Progress and Hope: A Historical Perspective on the OM Field Slide 4 Progress and Hope: A Historical Perspective on the OM Field Slide 5 Progress and Hope: A Historical Perspective on the OM Field Slide 6 Progress and Hope: A Historical Perspective on the OM Field Slide 7 Progress and Hope: A Historical Perspective on the OM Field Slide 8 Progress and Hope: A Historical Perspective on the OM Field Slide 9 Progress and Hope: A Historical Perspective on the OM Field Slide 10 Progress and Hope: A Historical Perspective on the OM Field Slide 11 Progress and Hope: A Historical Perspective on the OM Field Slide 12 Progress and Hope: A Historical Perspective on the OM Field Slide 13 Progress and Hope: A Historical Perspective on the OM Field Slide 14 Progress and Hope: A Historical Perspective on the OM Field Slide 15 Progress and Hope: A Historical Perspective on the OM Field Slide 16 Progress and Hope: A Historical Perspective on the OM Field Slide 17 Progress and Hope: A Historical Perspective on the OM Field Slide 18 Progress and Hope: A Historical Perspective on the OM Field Slide 19 Progress and Hope: A Historical Perspective on the OM Field Slide 20 Progress and Hope: A Historical Perspective on the OM Field Slide 21 Progress and Hope: A Historical Perspective on the OM Field Slide 22 Progress and Hope: A Historical Perspective on the OM Field Slide 23 Progress and Hope: A Historical Perspective on the OM Field Slide 24 Progress and Hope: A Historical Perspective on the OM Field Slide 25 Progress and Hope: A Historical Perspective on the OM Field Slide 26 Progress and Hope: A Historical Perspective on the OM Field Slide 27 Progress and Hope: A Historical Perspective on the OM Field Slide 28 Progress and Hope: A Historical Perspective on the OM Field Slide 29 Progress and Hope: A Historical Perspective on the OM Field Slide 30 Progress and Hope: A Historical Perspective on the OM Field Slide 31 Progress and Hope: A Historical Perspective on the OM Field Slide 32 Progress and Hope: A Historical Perspective on the OM Field Slide 33
Upcoming SlideShare
What to Upload to SlideShare
Next
Download to read offline and view in fullscreen.

0 Likes

Share

Download to read offline

Progress and Hope: A Historical Perspective on the OM Field

Download to read offline

Presentation by Kenneth Hovland, MD. Presented at the 2018 Eyes on a Cure: Patient & Caregiver Symposium, hosted by the Melanoma Research Foundation's CURE OM initiative.

Related Books

Free with a 30 day trial from Scribd

See all

Related Audiobooks

Free with a 30 day trial from Scribd

See all
  • Be the first to like this

Progress and Hope: A Historical Perspective on the OM Field

  1. 1. Progress and Hope: A Historical Perspective on the OM Field Kenneth Hovland, MD Ocular Melanoma Patient and Caregiver Symposium Denver, Colorado April 20-22, 2018
  2. 2. 50 years ago:
  3. 3. • Removal of the eye was the only option
  4. 4. Positive attitude!
  5. 5. • Nationally, at the AFIP (1949-1970) there was a 20% error in diagnosis !
  6. 6. Indirect ophthalmoscope (1960’s)
  7. 7. Photography
  8. 8. Ultrasonography (1970’s)
  9. 9. B-scan A-scan
  10. 10. Radiation (1970’s) • Large dose needed
  11. 11. Radioactive Iodine125 Proton beam plaque
  12. 12. Collaborative Ocular Melanoma Study (COMS 1986-2003) For Medium tumors (2.5 to 10 mm thick) ?any survival advantage with: Iodine-125 plaque vs Enucleation
  13. 13. 1500 patients in 40+ centers
  14. 14. Iodine-125 plaque vs.Enucleation  Survival is equal  Quality of life issues
  15. 15. • Cobalt 60 • Iodine 125 • Palladium 103 • Ruthenium 106
  16. 16. • In patients with Large tumors (>10 mm thick) (requiring enucleation anyway), would pre-operative external radiation help survival? • Answer: No
  17. 17. COMS • Now 40 additional centers in US and Canada with expertise to diagnose and treat ocular melanoma • Accuracy: 99.7% (Only 1 benign tumor in 1500 cases)
  18. 18. Frequency of ocular melanoma (5-6 per million) • Unchanged for many decades, • Compared with definite increase of skin melanoma (> 20 times more common)
  19. 19. Optical Coherence Tomography (OCT)
  20. 20. Magnetic Resonance Imaging (MRI)
  21. 21. Positron Emission Tomography (PET)
  22. 22. • Genetic aspects
  23. 23. Skin melanoma is different than ocular melanoma Skin Eye
  24. 24. Team approach for patients: • Ophthalmic oncologist • Radiation oncologist, physicists • Ultrasonographers • Ophthalmic photographers • Medical oncologist • Genetic counselors • Social services
  25. 25. Basic research
  26. 26. • A lot of progress has been made in the diagnosis and management of ocular melanoma
  27. 27. Challenges  Earlier detection  Decrease side effects of radiation  Better treatment for metastases
  28. 28. Thanks to Dr. Sara Selig, with her own personal experience with ocular melanoma, for bringing together such a range of personnel to discuss these challenges, and for her tireless efforts to make progress in the lives of patients.

Presentation by Kenneth Hovland, MD. Presented at the 2018 Eyes on a Cure: Patient & Caregiver Symposium, hosted by the Melanoma Research Foundation's CURE OM initiative.

Views

Total views

316

On Slideshare

0

From embeds

0

Number of embeds

5

Actions

Downloads

2

Shares

0

Comments

0

Likes

0

×