Successfully reported this slideshow.
We use your LinkedIn profile and activity data to personalize ads and to show you more relevant ads. You can change your ad preferences anytime.

Adult stem cells for chronic pain

50 views

Published on

Dr. Hughes discusses the various types of stem cells and their uses. He also talks about the science behind chronic pain

Published in: Health & Medicine
  • Be the first to comment

  • Be the first to like this

Adult stem cells for chronic pain

  1. 1. Adult Stem Cells for Chronic Pain Dr. John Hughes, DO January 24th, 2018
  2. 2. Dr. John Hughes, DO • Doctor of Osteopathy • From Georgia • Arizona College of Osteopathic Medicine - 2007 • Aspen Integrative Medicine - 2009 • TBI Therapy - 2014
  3. 3. Outline • What Are Stem Cells? • What Are Growth Factors? • How to Treat Chronic Pain
  4. 4. What Are Stem Cells? Defined Undifferentiated biological cells Divide and generate all cell types of the organ from which they originate Stimulate tissue re-growth and greater blood flow to the affected areas
  5. 5. • Mostly derived from embryos that develop from eggs in vitro • Expensive • Not autologous • Ethically controversial • Not readily available – research only What Are Stem Cells? Embryonic
  6. 6. • For the specific tissue or organ in which they live • Lung – Lung • Heart – Heart • Do not self-renew as easily • Difficult to find What Are Stem Cells? Tissue-Specific
  7. 7. • From bone marrow, fat, and cord blood • Immunomodulatory properties • On a development trajectory towards specific target tissues • Therapeutic effects are short- lived What Are Stem Cells? Mesenchymal
  8. 8. • Recently discovered in peripheral blood • Behave like embryonic stem cells • Give rise to all the cell types • Long lifespan What Are Stem Cells? Pluripotent
  9. 9. Stem Cell Potency Totipotent *Pluripotent* Multipotent Embryonic Peripheral Blood Mesenchymal
  10. 10. Stem Cell Uses Embryonic Peripheral Blood Mesenchymal • Research • Degenerative Diseases • Degenerative Diseases: • Diabetes • Osteoarthritis • Osteoporosis • Alzheimer's Disease • Regeneration: • Brain Injuries • Joint/Ligament Repair • Anti-aging • Post Cancer Treatment • Fertility • Same tissue Replacement • Systemic Inflammatory Conditions
  11. 11. What Are Growth Factors? • Signaling molecules between cells • Cytokines and hormones that bind to specific receptors • Promotes cell differentiation and maturation
  12. 12. Stem Cells and Growth Factors • Stem cells = seeds • Growth factors = water/soil/fertilizer/sunlight • Without growth factors, the seed cannot mature and grow
  13. 13. What Do Growth Factors Do? • Designed to improve metabolism of nutrients • Stimulate growth of collagen: cartilage, bone, ligaments, tendons, blood vessels, and neurons • Guide stem cells to area of injury • Nurture stem cells to maturity
  14. 14. Growth Factors + Stem Cell Uses • Chronic Sports Injuries (ex. Tennis Elbow, Achilles Tendonitis, and Runner’s Knee) • Degenerative Joint & Disc Disease • Chronic Sprains and Strains • Cervical, Thoracic, and Lumbar Spine Strains • Traumatic Brain injuries • Arthritic Joints • Shoulder Pain, Hip Pain, and Knee Pain • Ligament Laxity or Tears • Tendon and Ligament Injuries • Carpal Tunnel Syndrome
  15. 15. How to Treat Chronic Pain • Surgery – expensive, risky, potential side effects • Physical Therapy – only manages pain, therapeutic but not long term • Cortisone Injections – temporary fix, manages inflammation, rarely solves source of pain, potentially damaging • Regenerative Injection Therapy – natural, autologous, treats cause of pain rather than symptom, long term
  16. 16. Chronic Pain Treatment Costs • Surgery = $40,000 - $100,000 • Physical Therapy = $50 - $350 per session • Embryonic Stem Cells = only research purposes • Pluripotent Stem Cells = $8,000 - $10,000 • Mesenchymal Stem Cells = $7,000 - $300,000 • Platelet Rich Plasma (PRP) = $1,400 - $2,000
  17. 17. What Treatment Should You Choose?
  18. 18. 970-927-0308 | aspenintegrativemedicine.com

×