Tracking Drug Trade Names in Biomedical Literature - PowerPoint ...
Tracking Drug Trade Names
in Biomedical Literature
Embase offers several options for monitoring
drug products in the biomedical literature.
Because each method entails varying ways searches are
executed, results for each may vary slightly.
Choose the option(s) that best suit your research needs.
Use Quick Search for fast and simple queries.
Extensive search matches (or “maps”) a drug trade
name to its equivalent Emtree preferred term
(usually its INN generic name).
It also “explodes” it to retrieve narrower terms (if
any), and also searches keywords from article titles,
abstracts and other database fields.
This option usually retrieves most literature available
in Embase; it may not be completely comprehensive.
Preliminary results appear above.
Note that the product name OxyContin has mapped to —
and is searched as -- the preferred index term
oxycodone. This means that Embase looks for papers
indexed with oxycodone regardless of whether the name
OxyContin appears or not.
Click on a
to see its
Here, neither OxyContin nor
oxycodone appear in the
However, it does appear in the
Emtree drug index terms
field because the drug was
discussed in the body of the
original paper; therefore this
citation is still relevant.
Advanced Search provides many more search options, and
greater flexibility in query-building, than Quick Search.
As before, term mapping is automatically enabled (it can be
turned off, if desired).
Search also for synonyms… ensures that all possible variants
of a drug name are searched as well as the preferred drug term
currently used for indexing. Drug names occasionally change
over time, and old (replaced) names are retained in the Emtree
thesaurus as synonyms.
This option provides the most comprehensive retrieval.
Note the difference in retrieval when synonym
searching is included.
You can see the difference in the records retrieved by this
method by excluding them from the first search set using the
Boolean NOT operator, and then checking a few in detail.
Here, oxycodone does not appear as an index term, but it is
mentioned peripherally in the abstract.
Drug Search allows you
to take advantage of
special Embase drug
indexing — drug
subheadings and routes
of administration — for
more focused searching.
This option affords very
high search precision.
Note that mapping
to preferred drug
Note slight difference in retrieval from other search
Here, the set from Drug Search only finds articles with
the term oxycodone in the records’ index term fields;
synonyms and keywords are not searched.
The first several options work well when comprehensive
retrieval of a drug topic is needed.
To find articles on a specific drug product name, use Field Search
to search within the Drug Trade Name field.
Along with indexing generic names, Embase records also include drug
trade names (plus manufacturer names) whenever they are mentioned
within the text of the original article.
This allows you to track individual products in published research literature:
• For pharmaceutical safety and efficacy reporting requirements
• For maintaining internal product databases
• For corporate intelligence (tracking competitor products)
• And much more
Check drug trade name from the list of
available data fields to look for the
Note: This option does not enable index term mapping.
Only the selected data field(s) are searched.
Consider using look-up tables to find any
spelling variations of drug names. Add to my
Search automatically posts them to the Field
Search box above.
For more complete results, consider including
any possible segmented variations as well:
Oxy Contin, etc.
Note the dramatic difference in hits when only
specific trade names are searched.
Click on a title to view indexing.
Note the preferred generic term oxycodone in
the index fields.
Drug trade names (plus drug manufacturer
names and countries, when available) are
displayed separately in their own fields.
Within Emtree Tool, you can use a drug product name to identify
its preferred Emtree index term, to see other trade names
associated with it, and learn other information about it.
Type a trade name in the Find Term box. The correct index
terms appears as a link below. Follow the link for more
In the hierarchical Emtree
thesaurus, individual drugs
are grouped within drug
families according to their
chemical structure and/or
Synonyms appear at the
bottom of the page.
Synonyms include alternate drug and disease names, non-INN generic
nomenclature, trade names from around the world, chemical compound names,
laboratory codes, enzyme codes, and MeSH subject headings from MEDLINE.
If your search includes any of these names, it will automatically map to the
matching Emtree term — thus ensuring accurate and complete retrieval.
Additional information from
Dictionary is available for
Links from the drug’s
Service registry number(s)
out to PubChem for
additional chemical data.
PubChem, from the National Center for
Biotechnology Information, provides a wealth of
additional data on chemical structures,
properties, mechanisms of action and much