National and
Affiliate
Research
Programs
of the
American
Heart
Association
Rajini Reddy Mudhasani, PhD
Type of Award: Post...
2
Mission and Goal
3
Mission
Building healthier lives,
free from
cardiovascular
diseases and stroke
Michaela Gagne
Miss Massachusetts and AHA...
4
Goal of the AHA
Research Programs
The goal of the American Heart Association
Research Programs is the acquisition of new...
5
Milestones in AHA Research
6
1985. Drs. Joseph Goldstein
and Michael Brown, funded by
the Association in 1972, '73 and
'75, are awarded the Nobel
Pri...
7
1992. Drs. Edwin
Krebs and Edmond
Fischer win the Nobel
Prize in Physiology or
Medicine for their
discovery of how
prote...
8
1998. Three Americans are
awarded the Nobel Prize in
Physiology or Medicine for
their discovery of nitric oxide, a
color...
9
2003. Dr. Peter Agre is
awarded the Nobel Prize
in Chemistry for his
discovery of aquaporins,
proteins that govern the
m...
10
The Importance of AHA Research
11
The AHA’s Investment in
Research Compared to Other
Major Health Agencies
In 2007, the AHA
invested more in
research fun...
12
Life Cycle of a Research ApplicationLife Cycle of a Research Application
HmmHmm
……
ApplicationApplication
submittedsubm...
13
The AHA Research Program
Today
14
• To avoid losing a
generation of scientists, the
AHA now awards about two-
thirds of its research dollars
to early car...
16
Types of Research:
Basic
• Basic Research is a synonym for fundamental research,
which is the study of life processes t...
17
Types of Research:
Clinical
• Clinical Research addresses important questions of
normal function and disease using huma...
18
Types of Research:
Population Health
• Population Health Research is the science of studying
the distribution and deter...
19
Our National and Affiliate
Investigator-Initiated
Research Programs
Investigator-Initiated
Research investigates a
ques...
20
Greater Southeast Affiliate
Research Programs
Program
Target
Audience
Annual
Minimum
Duration
Health Science
Student
Fe...
21
Success Rates GSA-
July 08
• Grant-in-Aid 18.89%
• Beginning Grant-in-Aid 14.29%
• Postdoctoral Fellowship 20.39%
Predo...
22
National Investigator-Initiated
Research Programs
Program Description
Award
Amount
Duration
Fellow-to-
Faculty
Transiti...
23
National Investigator-Initiated
Research Programs
Program Description
Award
Amount
Duration
Scientist
Development
Grant...
24
National Investigator-Initiated
Research Programs
Program Description
Award
Amount
Duration
Innovative
Research
Grant
T...
25
Success Rates AHA
National- Jan 09
• Scientist Development Grant 21.33%
• Established Investigator Grant 14.78%
• Clini...
26
AHA Affiliates
Pacific Mountain
Western States
Midwest
South Central
Greater Southeast
Great Rivers
Mid-Atlantic
Founde...
27
AHA Research Consortia
The AHA’s peer
review system is
divided into four
regional consortia.
Consortia are groups
of fu...
28
Peer Review
• Formal process
for reviewing
and ranking
applications
• Peer
Reviewers
volunteer their
time and
expertise...
29
Funded and Unfunded
Meritorious Grants
Satoshi Komatsu, PhD (right)
Type of Award: Scientist Development Grant
• All re...
30
All the Information
You Want
Extensive information about our Research Program can be
found on our website. The website ...
31
Questions
Upcoming SlideShare
Loading in …5
×

National and Affiliate Research Programs of the American Heart ...

580 views

Published on

0 Comments
1 Like
Statistics
Notes
  • Be the first to comment

No Downloads
Views
Total views
580
On SlideShare
0
From Embeds
0
Number of Embeds
1
Actions
Shares
0
Downloads
1
Comments
0
Likes
1
Embeds 0
No embeds

No notes for slide
  • <number>
    01/29/15
  • National and Affiliate Research Programs of the American Heart ...

    1. 1. National and Affiliate Research Programs of the American Heart Association Rajini Reddy Mudhasani, PhD Type of Award: Postdoctoral Fellowship
    2. 2. 2 Mission and Goal
    3. 3. 3 Mission Building healthier lives, free from cardiovascular diseases and stroke Michaela Gagne Miss Massachusetts and AHA Volunteer I truly appreciate how fortunate I am to have escaped potential fatality. It’s because of American Heart Association-funded research that I am alive, well and physically active today. It’s also the reason I’m doing everything in my power to motivate others to support the heart association’s cause and lead a heart healthy life.
    4. 4. 4 Goal of the AHA Research Programs The goal of the American Heart Association Research Programs is the acquisition of new knowledge broadly related to the normal function of the cardiovascular system and the causes, prevention, treatment or control of cardiovascular diseases and stroke.
    5. 5. 5 Milestones in AHA Research
    6. 6. 6 1985. Drs. Joseph Goldstein and Michael Brown, funded by the Association in 1972, '73 and '75, are awarded the Nobel Prize in Physiology or Medicine for their research on the role of low-density lipoprotein receptors in controlling blood cholesterol levels. Their research provides new insights into the ways cholesterol enters body cells and why cholesterol levels may become too high.
    7. 7. 7 1992. Drs. Edwin Krebs and Edmond Fischer win the Nobel Prize in Physiology or Medicine for their discovery of how proteins are switched on to perform functions within cells. Dr. Krebs, whose research was supported in part by the American Heart Association, received the Association's Research Achievement Award in 1987.
    8. 8. 8 1998. Three Americans are awarded the Nobel Prize in Physiology or Medicine for their discovery of nitric oxide, a colorless gas that makes blood vessels dilate by relaxing the vessels' smooth muscle. The American Heart Association funded one of the awardees, Dr. Robert Furchgott, from 1952 to 1954.
    9. 9. 9 2003. Dr. Peter Agre is awarded the Nobel Prize in Chemistry for his discovery of aquaporins, proteins that govern the movement of water in and out of cells. Dr. Agre received American Heart Association Established Investigator funding from 1987-92.
    10. 10. 10 The Importance of AHA Research
    11. 11. 11 The AHA’s Investment in Research Compared to Other Major Health Agencies In 2007, the AHA invested more in research funding than any other health agency. Organization 2007 Research Expense A American Heart Association 147,500,000 B American Cancer Society 146,933,000 C Juvenile Diabetes Research Foundation 146,614,000 D American Diabetes Association 54,341,000 E National Multiple Sclerosis Society 50,940,905 F March of Dimes (includes research and medical support) 46,323,000 G Alzheimer’s Association 37,593,000 H Muscular Dystrophy Association 37,313,847 Source: Respective Health Agencies’ 2007 Annual Reports
    12. 12. 12 Life Cycle of a Research ApplicationLife Cycle of a Research Application HmmHmm …… ApplicationApplication submittedsubmitted An idea beginsAn idea begins Peer ReviewPeer Review CommitteeCommittee E-mailE-mail notificationnotification ResearchResearch completedcompleted Yea!Yea! ReportsReports PublishedPublished FindingsFindings translatedtranslated Assigned toAssigned to reviewersreviewers CritiqueCritique developeddeveloped Rank-Rank- ordered listordered list ResearchResearch CommitteeCommittee $$ FundedFunded
    13. 13. 13 The AHA Research Program Today
    14. 14. 14 • To avoid losing a generation of scientists, the AHA now awards about two- thirds of its research dollars to early career investigators. • Successful early career investigators then go on to secure NIH and other grants. Zoltan Ungvari, M.D., Ph.D. Type of Award: Scientist Development Grant
    15. 15. 16 Types of Research: Basic • Basic Research is a synonym for fundamental research, which is the study of life processes that are universal in their application to scientific knowledge. – Example of Basic Research on Childhood Obesity: • Early life determinants of metabolic syndrome in animal models: interaction of perinatal environment and genetic predisposition
    16. 16. 17 Types of Research: Clinical • Clinical Research addresses important questions of normal function and disease using human subjects. – Example of Clinical Research on Childhood Obesity: • Binge Eating, Purging, and Cardiovascular Risk in Adolescents; The Effect of Weight-Loss Diets Varying in Protein and Carbohydrate Content on Markers of Cardiovascular Risk
    17. 17. 18 Types of Research: Population Health • Population Health Research is the science of studying the distribution and determinants of health status as influenced by social, economic and physical environments, human biology, health policy and services and of preventing disease, prolonging life and promoting health at the population levels. – Example of Population Health Research on Childhood Obesity: • Walking School Bus Approach to Increase Physical Activity And Attenuate BMI of Elementary School Children
    18. 18. 19 Our National and Affiliate Investigator-Initiated Research Programs Investigator-Initiated Research investigates a question or hypothesis that the researcher has defined. The AHA's publicly donated dollars are used to support this type of research. Joseph M. Miano, PhD Type of Award: Grant-in-Aid
    19. 19. 20 Greater Southeast Affiliate Research Programs Program Target Audience Annual Minimum Duration Health Science Student Fellowship Predoctoral health sciences students $13,500/year 2 years to the institution Predoctoral PhD, MD students $21,770/year stipend 2 years Postdoctoral PhD, MD students, not yet independent Sliding scale, $35,568 - $51,036 year stipend 2 years Clinical Research Program* *New in 2009 MA, MD, DO or PhD not yet independent $75,000/year 2 years Beginning Grant in Aid 1st Faculty/Staff appt. through Asst. Prof. $66,000/year 2 years Grant in Aid Faculty/Staff pursuing independent research $82,000/year 2 years
    20. 20. 21 Success Rates GSA- July 08 • Grant-in-Aid 18.89% • Beginning Grant-in-Aid 14.29% • Postdoctoral Fellowship 20.39% Predoctoral Fellowship 34.92% • Health Sciences Fellowship 100.00% • Total for Greater Southeast Affiliate $11,341,448.00 22.63%
    21. 21. 22 National Investigator-Initiated Research Programs Program Description Award Amount Duration Fellow-to- Faculty Transition Awards To provide funding for beginning physician- scientists with outstanding potential for careers in cardiovascular and stroke research $593,000 over 5 years 5 years Clinical Research Program To encourage early career investigators who have appropriate and supportive mentoring relationships to engage in high quality introductory and pilot clinical studies that will guide future strategies for reducing cardiovascular disease and stroke while fostering new research in clinical and translational science, and encouraging community- and population-based activities $100,000 ($50,000/ year) 2 years
    22. 22. 23 National Investigator-Initiated Research Programs Program Description Award Amount Duration Scientist Development Grants To support highly promising beginning scientists in their progress toward independence; bridges the gap between completion of research training and readiness for completion as an independent investigator $308,000 ($77,000/ year) 4 years Established Investigator Awards To support mid-term investigators with unusual promise, a rapidly growing research career and an established record of accomplishments; candidates have a demonstrated commitment to cardiovascular or cerebrovascular science as indicated by prior publication history and scientific accomplishments $500,000 ($100,000/ year, project support) 5 years
    23. 23. 24 National Investigator-Initiated Research Programs Program Description Award Amount Duration Innovative Research Grant To support highly innovative, high-risk, high-reward research that could ultimately lead to critical discoveries or major advancements that will accelerate the field of cardiovascular and stroke research. $150,000 ($75,000/ year) 2 years
    24. 24. 25 Success Rates AHA National- Jan 09 • Scientist Development Grant 21.33% • Established Investigator Grant 14.78% • Clinical Research Program 25.58% • Innovative Research Grant 2.90% • Total AHA National Research Program $30.56 Million 11.12%
    25. 25. 26 AHA Affiliates Pacific Mountain Western States Midwest South Central Greater Southeast Great Rivers Mid-Atlantic Founders
    26. 26. 27 AHA Research Consortia The AHA’s peer review system is divided into four regional consortia. Consortia are groups of funding compo- nents that conduct peer review together. Individual consortium review committees review applications in specific science areas.
    27. 27. 28 Peer Review • Formal process for reviewing and ranking applications • Peer Reviewers volunteer their time and expertise • At least 12 reviewers on each peer review committee
    28. 28. 29 Funded and Unfunded Meritorious Grants Satoshi Komatsu, PhD (right) Type of Award: Scientist Development Grant • All reviewed applications are scored and ranked. • We would fund all applications deemed highly meritorious (above the 30th percentile) if we had the resources to do so.
    29. 29. 30 All the Information You Want Extensive information about our Research Program can be found on our website. The website also offers a glossary of the types of research that we fund.
    30. 30. 31 Questions

    ×