– 1,1-dichloro-2,2-bis[p-chlorophenyl] ethane
– a degradation of DDT
– also dangerous to environment
Dangers of DDT
• Birds are major target species
MOA in Birds
• Inhibits Ca-dependent ATPases
• Egg shell thinning
• Increased risk of damage to eggs
Birds affected by DDT
• Brown Pelican
How DDT “helped”
• Boomerang Paradigm
• Increased awareness of ecotoxicity
• In conclusion, DDT is an insecticide that was used heavily from
the late 1930’s to the early 1970’s
• Throughout this time there were several populations of birds
that declined rapidly
• DDT has been one of the most widely influential pesticides to
help gain the attention of the impact we have on the
• Casarett, Louis J., John Doull, and Curtis D. Klaassen. "Chapter
29/Ecotoxicology." Casarett and Doull's Toxicology: The Basic
Science of Poisons. New York: McGraw-Hill, 2008. 1176-177.
• Michael, C. Newman. Fundamentals of Ecotoxicology, Third
EditionMichael C. Newman. Fundamentals of Ecotoxicology,
Third Edi: CRC, 2009. Print.
• "DDT - A Brief History and Status | Pesticides | US EPA." EPA.
Environmental Protection Agency, n.d. Web. 18 Nov. 2013.
• Dr. Baer’s power points from clinical toxicology
• Google images