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NUCLEOTIDES
&
NUCLEOSIDES
NUCLEOTIDES
• The monomer of the nucleic acid
• Phosphorylated nucleoside
• Occurs mono di and tri phosphate group
NUCLEOSIDES
• Formed when bases are attached to the pentose
sugar, D-ribose or 2-deoxy-D-ribose.
COMPONENTS
Has three components
• Pentose sugar Ribose/Deoxyribose
• Phosphate Group
• Nitrogenous base Purine/Pyrimidine
STRUCTURE OF NUCLEOTIDE
RIBOSE SUGAR
• Pentose(Five carbon sugar)
• Pentose Sugar may b D-Ribose or 2-deoxy-D-Ribose
BASES
• Two types of nitrogenous bases;
-the purines and pyrimidines are present
in nucleic acid.
-Purines are Double ringed structures.
-Pyrimidines are Single ringed structures.
• When a Second Phosphate gets esterified to the
existing Phosphate Group, a nucleoside di phosphate
is regenerated
• The attachment of third phosphate group results in
the formation of a nucleoside triphosphate.
• The nucleic acids (DNA and RNA) are polymers of
nucleoside monophosphate.
PHOSPHATE GROUP
SUGAR+BASE+PHOSPHATE GROUP=NUCLEOTIDES
FUNCTIONS
• Nucleotides are precursors of nucleic acid,
deoxyribonucleic acid(DNA) and ribonucleic
acid(RNA).
• The nucleic acid are concerned with storage and
transfer of genetic information.
• Nucleosides are used as antiviral and anticancer
agent in the medicine.
FUNCTIONS
• The universal currency of energy, namely ATP, is a
nucleotide derivative.
• Nucleotides are precursors of important co-enzymes
like
-NAD+ and FAD and
-metabolic regulators such as cAMP and
cGMP.
Nucleotides nucleosides

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Nucleotides nucleosides

  • 2. NUCLEOTIDES • The monomer of the nucleic acid • Phosphorylated nucleoside • Occurs mono di and tri phosphate group NUCLEOSIDES • Formed when bases are attached to the pentose sugar, D-ribose or 2-deoxy-D-ribose.
  • 3. COMPONENTS Has three components • Pentose sugar Ribose/Deoxyribose • Phosphate Group • Nitrogenous base Purine/Pyrimidine
  • 5. RIBOSE SUGAR • Pentose(Five carbon sugar) • Pentose Sugar may b D-Ribose or 2-deoxy-D-Ribose
  • 6. BASES • Two types of nitrogenous bases; -the purines and pyrimidines are present in nucleic acid. -Purines are Double ringed structures. -Pyrimidines are Single ringed structures.
  • 7. • When a Second Phosphate gets esterified to the existing Phosphate Group, a nucleoside di phosphate is regenerated • The attachment of third phosphate group results in the formation of a nucleoside triphosphate. • The nucleic acids (DNA and RNA) are polymers of nucleoside monophosphate. PHOSPHATE GROUP
  • 8.
  • 10. FUNCTIONS • Nucleotides are precursors of nucleic acid, deoxyribonucleic acid(DNA) and ribonucleic acid(RNA). • The nucleic acid are concerned with storage and transfer of genetic information. • Nucleosides are used as antiviral and anticancer agent in the medicine.
  • 11. FUNCTIONS • The universal currency of energy, namely ATP, is a nucleotide derivative. • Nucleotides are precursors of important co-enzymes like -NAD+ and FAD and -metabolic regulators such as cAMP and cGMP.