Improved diagnostic test benefits children with acute myeloid
MOLECULAR BIOLOGY MARCOS RESTREPO ARANGOSECOND YEAR MEDICAL STUDENT MEDELLÍN 2013
The laboratory techniques that scientist are tryingto improve are focus in the objetive of facilitate tothe doctor the way of treatment of some diseaseby understanding the molecular compotation ofthese. So this way the patients are going to receivemore effective’s treatment. Other one is todiagnostic rapidly the presence or the inition of adisease.
The flow citometry is a technique that is use in laboratorys to find cells that are extrange in a sample, that has 1000 cell. So the technique classifiedthe cancer cells from the normal cells.
The idea of this technique is to improve it with the objective toidentify minimal residual disease. With identifying this minimal trail of pathology it would be easier to focus the treatment and identify which patients are allowed to receive some special handling.
The study also make a comparison of the methods that are usually used to identify de ALL and AML. With the objective to identify which techniqueis better to handling the patients. Themethods that the study compares arethe evaluation by microscopy, the PCR and the flow cytometry.
As result of the study the better wasthe flow cytometry. Because the PCR has false positives result. The microscopy evaluation results very difficult to identify the cancer cells from normal cells. And flow cytometry can detect de minimal residual disease.
Know the knowledge of the microscopy things take more importance in the medical worldbecause the new explanation of thebehavior of a disease. In these case the scientist are trying to find why some malformation of the fribronectin fiber are related with the development of some pathologies.
The fibronectin fibers are related with the development of some disease. The scientist try to find probes that can make easier to follow the mechanism of malformation of this fiber. Theimportant is to understand how this malformation cant influence in the pathology.
In the experiment the scientist finedsome probes that permit identify theproteins and molecules that areinvolved in the process of themalformation of the fibronectinfiber. And with this understandbetter.
With that probes they can not onlysee how do the deformation takeplace, they can regulate this, withsignalization, and control de expressof the sites that are involved in thedeformation.
Bio molecular tastes and techniqueshave a very important application tomedicine. These applications arefocus to different objective, but all ofthem are do it to find the welfare ofthe patient.
Is very interest to find the bettertreatment of a patient that has aspecific pathology. This methodimproves the singular treatment andthe survival patient prognosis.
See how the pathology develop inthe patients with the particularcharacteristic of them, we can makea more central treatment and maybebe more effective to bite the disease.With these improving the medicalexecution.
Diagnostic pathology before expressthe real disease. This objective wouldrepresent a very important form toknow how to proceed with a patientthat is in risk