De Novo Cerebral Aneurysms: How often do they happen? Macquarie Neurosurgery Evidence Based Surgery presentation Date: March 8, 2012 Nirav J. Patel EBS presentation 1
Clinical case21F with a PMHx of SAH, clipping of rightparaclinoid aneurysm.No HTNFHx: noneSHx: Non-smoker6 years later left superior hypophysealaneurysm detected.How often should treated cerebral aneurysm patientsbe imaged?
Searchable question: What is the riskof developing a new aneurysm in apatient who has cerebral aneurysm(s)?• P = Patients with cerebral aneurysms, who develop another cerebral aneurysm.• I=• C=• O = What is the incidence? The risk of developing a new aneurysm?
Search strategy P Intracranial Aneurysm/ AND De novo.mp OR new aneurysm.mp I NA C NA O Incidence/ or incidence.mp Or Risk Factors/
Medline Search results 1Preliminary search using “treated aneurysm”.
Conclusions1. De novo aneurysm definitely happen.2. .5-1.2% annual risk of development3. Maybe higher in younger females4. Multiple aneurysms increase risk5. Don’t know about HTN, smoking, family history How often should treated cerebral aneurysm patients be imaged? < 5yrs.