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M2i2 2014 Collaborations and Studies


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M2i2 was launched in 2013 with the mandate of building strategic collaborations to enhance health IT and data driven capabilities so we can advance science, improve public health and clinical care, and support patient engagement.

This prospectus illustrates our launched collaborations over the past year with leading organizations across healthcare, including: academic medical centers, payers, informatics research hubs, startups, and health information technology organizations.

Contact: Aman Bhandari or Sachin Jain: m2i2 at merck dot com

Learn More about M2i2 Initiatives:

Dr. Sachin Jain on HBR Blog:

Maccabi Healthcare Services Data Initiative:

Regenstrief Institute Evidence-based Care Collaboration:

Northwestern Medicine, Walgreens & Alliance of Chicago Prescription Instructions Study:

CECITY Fracture Liaison Care Coordination Study:

StartX Life Sciences Incubator:

Boston Children's Hospital Social Media & Insomnia Study:

Published in: Health & Medicine
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M2i2 2014 Collaborations and Studies

  1. 1. Merck Medical Information and Innovation Building an ecosystem of strategic collaborations to enhance health IT and data-driven capabilities for our collaborators and Merck so we can work together to advance science, improve public health and clinical care, and support patient engagement. 2014 Collaborations and Studies It’s a banner year for innovative collaborations with organizations that have unlocked mutual value across the ecosystem. C O L L A B O R ATO R S KEY AREAS Personalized Delivery of Care HPV Osteoporosis Comparative Effectiveness Clinical Decision Support EMR Alzheimer's Health IT Diabetes Adherence Disease Areas Population Health Cardiovascular Oncology Hepatitis C Content Areas Global Data Access Patient Voice Insomnia Patient Engagement
  2. 2. C O L L A B O R AT I O N S A N D S T U D I E S M2i2’s global strategic collaborations focus on: health information technology / digital health and access to data and external analysis. They leverage Merck’s scale and expertise to enhance data-driven approaches, improve population health and clinical care, and support patient engagement while giving Merck access to leading-edge talent, innovation and opportunities in the context of marketplace changes driven by the Affordable Care and HITECH Acts. Northwestern Maccabi StartX M2i2 is collaborating with Northwestern University, Alliance of Chicago, and Walgreens on a landmark health IT interventional study evaluating the impact of providing simplified and clear medication instructions. Currently, physician practices and pharmacies use different electronic record systems for writing prescriptions and translating them onto the medicine label. Maccabi Healthcare, one of Israel’s largest health systems, has over 20 years of clinical and claims data history. Maccabi and Merck will apply technical and information research capabilities to draw insights from Maccabi’s data to support personalized health care delivery strategies across several therapeutic areas, including prevalent and costly chronic diseases. Merck joined StartX, a Stanford University non-profit spinoff in the heart of Silicon Valley, as a corporate partner to provide strategic guidance to promising health technology entrepreneurs to build innovative healthcare solutions. As a corporate partner, Merck will have access to disruptive innovations in data, analytics and digital health as well as exposure to world class talent and ideas. Regenstrief Institute Humedica (Optum) Merck’s multi-year partnership with the Regenstrief Institute is a novel collaboration between a pharmaceutical company and a health information exchange. The scale of the Institute’s data assets (approximately 13M unique patients) combined with their informatics capabilities will allow Merck to advance our insights in osteoporosis, HPV, diabetes and oncology. Researchers across Merck are utilizing Humedica's clinical intelligence platform to derive real world insights. Moving beyond claims-based analysis, the Humedica asset captures lab results, vital signs and includes unique natural language processed data that supports Merck’s observational research efforts in real-world settings. CBMI at Harvard Medical School Health Data Consortium PatientsLikeMe (Merck | HPN ACO Challenge) HDC brings together organizations from government, non-profit and the private sector to advocate for open, intelligent use of data to improve health. As part of the Consortium, Merck and Heritage Provider Network, an ACO, are hosting an innovation challenge – the first pharma/ACO collaboration of its kind – to find solutions that improve care plan adherence. PatientsLikeMe, a patient network with over 250,000 members, helps increase understanding of the real-world disease burden of a variety of conditions. The community facet of PLM’s platform unlocks insight into patient perspectives that helps patients learn from each other and will help Merck's researchers better understand patients and develop more effective solutions. The Center for Biomedical Informatics created the Informatics for Integrating Biology & the Bedside (i2b2) platform, adopted by over 100 academic health centers in linking their EMR systems with biobank and genomic information. CBMI’s expertise in digital libraries enables Merck to co-develop methodology to analyze the pathophysiology and underlying mechanisms of insomnia and physician prescribing behavior. Boston Children’s Hospital | Harvard M2i2 is working with the premier computational epidemiology lab in the US on an unique study analyzing data from Twitter to create digital definitions for insomnia. This research also aims to contribute new and meaningful information to the scientific community on the predictors of sleep deprivation based on social media-related behaviors. Practice Fusion CECity Huaxi Hospital M2i2 is accelerating care delivery innovation by partnering with Practice Fusion, a cloudbased EMR provider engaged in point-of-care CDS and population health management. Merck and Practice Fusion are co-developing communications to roll into the CDS and the EMR intelligence platform to help improve quality of care. CECity, a cloud-based technology company, is collaborating with the National Bone Health Alliance, NOF and three academic medical centers in a demonstration study to assess the potential to improve quality of care in patients with osteoporosis. CECity will use their platform to study the ability to scale quality improvement and coordinate care to address care gaps and drive improvement for post-fracture patients. M2i2 is supporting a novel research collaboration with West China Hospital of Sichuan University (Huaxi Hospital), the largest single-site hospital in the world and a leading medical center of West China, to explore the impact of diabetes on mortality in non-ICU inpatients. Allscripts Smart Patients M2i2 is accelerating care delivery innovation by partnering with Allscripts, a healthcare IT focused company and EMR provider. Merck and Allscripts are co-developing CDS content based on industry guidelines that would be accessible through the EMR at the point-of-care. Smart Patients is an online community where cancer patients and caregivers learn from each other about treatments, clinical trials and the latest scientific breakthroughs. Merck is leveraging real-world insights from the Smart Patients network to better understand patient, clinician and caregiver voices and perspectives. Data & Analytics Health Information Technology / Digital Health
  3. 3. T H A N K YO U ! We would like to thank our colleagues within and outside of Merck. The M2i2 community is extremely fortunate to welcome a premier class of health IT and data organizations with a shared vision for improving health. And we are lucky to have world-class informatics and research colleagues working with our collaborators around the world to drive value for patients. TEAM Merck Medical Information and Innovation Our senior staff represents diverse perspectives from the top ranks of government, clinical medicine, and industry. Dr. Sachin Jain Chief Medical Information and Innovation Officer (CMIO) Additionally: Lecturer in Health Care Policy and Medicine, Harvard Medical School; attending physician, Department of Veterans Affairs Previously: Senior Advisor to the Administrator of CMS, where he helped lead implementation of the Affordable Care Act and the launch of the Center for Medicare and Medicaid Innovation Dr. Tom Tsang Paulien Meijer Dr. Aman Bhandari Executive Director Executive Director Director Previously: Staff member in the House of Representatives, where he authored critical portions of the Affordable Care Act and assisted in Centers for Medicare and Medicaid Innovation Previously: Long-time leader in Merck's Global Market Access Organization Previously: Held positions at the White House, Centers for Medicare and Medicaid Services, Genentech and the VA Chris Yu Bryan Mallitz Arnaub Chatterjee Director Director Associate Director Previously: SVP, U.S. Healthcare, Voxiva, a leading mobile health patient engagement company Previously: Leadership positions in health IT strategy and development at Merck Previously: Special Assistant to the CTO of US Department of Health and Human Services and former management consultant at Deloitte For questions please email Aman Bhandari or Sachin Jain: Today's Merck is a global healthcare leader working to help the world be well. Merck is known as MSD outside the United States and Canada. Through our prescription medicines, vaccines, biologic therapies, and consumer care and animal health products, we work with customers and operate in more than 140 countries to deliver innovative health solutions. We also demonstrate our commitment to increasing access to healthcare through far-reaching policies, programs and partnerships. For more information, visit and connect with us on Twitter, Facebook and YouTube.