Some Information on Acute Promyelocytic Leukemia

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Some Information on Acute Promyelocytic Leukemia

  1. 1. Some Information on Acute Promyelocytic Leukemia
  2. 2. •In the United States, acute promyelocytic leukemia affects approximately one out of every 250,000 people. The disease is a type of bone marrow cancer affecting the hematopoietic stem cells, which create platelets, white blood cells, and red blood cells. The three types of cells play important roles in the body, ranging from carrying oxygen and fighting disease to helping blood clot. Acute promyelocytic leukemia causes too many undeveloped white blood cells to accumulate in bone marrow, eventually creating a shortage of other blood cells in the body.
  3. 3. •Symptoms of the disease often result from decreased clotting ability caused by lack of platelets and substances released by cancerous cells. A person with acute promyelocytic leukemia may suffer from easy bruising and excessive nosebleeds or menstrual bleeding. He or she may also develop petechiae, small red dots beneath the skin, or show signs of anemia, like excessive tiredness and pale skin. The disease has been linked to changes in two genes but is not inherited.

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