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Asymptomatic Bacteriuria (ASB) in Pregnancy ( for public awareness )Dr. Sharda Jain Lifecare Centre


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Asymptomatic Bacteriuria (ASB) in Pregnancy ( for public awareness ) Dr. Sharda jain LIFECARE CENTRE

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Asymptomatic Bacteriuria (ASB) in Pregnancy ( for public awareness )Dr. Sharda Jain Lifecare Centre

  1. 1. Asymptomatic Bacteriuria (ASB) in Pregnancy ( for public awarness ) DR. SHARDA JAIN DR. JYOTI AGARWAL …Caring hearts, healing hands
  2. 2. Upto 1 out of 10 pregnant women suffer from ASB 1. Small FM et al. antibiotics for asymptomatic bacteriuria in pregnancy. Cochrane database systrev. 2015 Aug 7;8:CD000490
  3. 3. Early detection & prompt treatment is necessary to avoid consequences 1’2 • Progression acute pyelonephritis (Upto 30% cases) • Increased risk of premature delivery & low birth weight 1. Small FM et al.antibiotics for asymptomatic bacteriuria in pregnancy. Cochrane database systRev. 2015 Aug 7;8:CD000490 2. Prakash j. the kidney in pregnancy: A journey: A journey of three decedes. India J nephto;. 2012May;may;22(3);159-67
  4. 4. SCREENING • Pregnant women should be offered routine screening for ASB* by midstream routine urine examination 3 • Urine culture should be asked where indicated 3 *ASB- Asymptomatic Bacteriuria.; 3. ICOG FOGSI recommendations for good clinical practice. Routine antenatal care for the healthy pregnant women. Available 05,2016
  5. 5. DIAGNOSIS • Mid – stream sample of urine (MSU) showing bacterial growth ≥ 105cfu/ml in two consecutive sample in women without symptoms from the urinary tract4 cfu;:colony-forming unit 4. Grade M et al. guidelines on urological infection. EAU 201 (update on march 2015; cited on : April 05, 2016). Available at:
  6. 6. MANAGEMENT • IDSA2005GUIDELINE ON ASYMPTOMATIC BACTERIURIA IN ADULTS, RECOMMENDS- 5 * pregnant women with positive urine culture report should be treated (A-I)˄,5 The duration of antimicrobial therapy should be 3-7 days (A-II) ˄,5 ˄ IDSA clinical grading system:5 Strength of recommendation :A good evidence to support a recommendation for use; should always be offered ofevidence: 1- evidence from ≥ 1 properly randomized, controlled trial; ii evidence ≥ 1 well designed clinical trial , wothout rendomization ; from cohort or case controlled analysis syudies ( preferably from 11 center); from multiple time – series; or from dramatic results from uncontrolled experiments.
  7. 7. SANFORD GUIDELINES 2015 ORAL CEPHALOSPORIN AS ONE OF THE AGENTS IN ASB* DURING PREGNANCY *ASB-asymptomatoc bacteriuria 6. Gilbert DN et al. the sanford guide to antimicrobial therapy 2015, 45th edition. Sperryville, USA: antimicrobial therapy, inc; January 2015: pg.35 7. Ceftum tables prescribing information. Glaxosmithkline, india version: CEF/PI/IN/2015/01 dated 28 january 2015
  8. 8. Special care in patients allergic to pencillin or beta lactams Use of CEFTUM in pregnancy & lactations: There is no experimental evidence of embryopathic or teratogenic effects attributable to CEFTUM but, as with all drugs, it should be administered with caution during the early months of pregnancy. Cefuroxime is excreted in human milk, & consequently caution should be exercised when CEFTUM is administered to a nursing mother
  9. 9. ADDRESS 11 Gagan Vihar, Near Karkari Morh Flyover, Delhi - 51 CONTACT US 9650588339 9599044257 011-22414049 WEBSITE : ISO 14001:2004 (EMS) …..Caring hearts, healing hands ISO 9001:2008 26 Year In your service