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TAT in risk detection and prevention of cardiovascular disease

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TAT ( TELOMERE ANALYSIS TEST) USED TO COMPLEMENT TRADITIONAL CARDIOVASCULAR TESTS IN ORDER TO PROVIDE MORE COMPREHENSIVE ANALYSIS AND IDENTIFY THE RISKS OF DEVELOPING CARDIOVASCULAR PROBLEMS AT AN EARLIER STAGE

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TAT in risk detection and prevention of cardiovascular disease

  1. 1. TAT IN RISK DETECTION AND PREVENTION OF CARDIOVASCULAR DISEASE
  2. 2. TELOMERE LENGTH INDEPENDENT RISK FACTOR FOR CVD TELOMERE MEASUREMENT CAN IDENTIFY HIGH RISK INDIVIDUALS WITH SHORT TELOMERES TAT ( TELOMERE ANALYSIS TEST) USED TO COMPLEMENT TRADITIONAL CARDIOVASCULAR TESTS IN ORDER TO PROVIDE MORE COMPREHENSIVE ANALYSIS AND  IDENTIFY THE RISKS OF DEVELOPING CARDIOVASCULAR PROBLEMS AT AN EARLIER STAGE
  3. 3. REDUCED TELOMERE LENGTHS ARE FOUND IN PATIENTS WITH CARDIOVASCULAR RISK FACTORS SUCH AS: ATHEROSCLEROSIS HYPERTENSION OBESITY DIABETES (ESPECIALLY TYPE 2) SMOKING PHYSICAL INACTIVITY STRESS CHRONIC INFECTIONS
  4. 4. A positive effect on telomere length is found with increased physical activity, statin treatment, and higher blood levels of omega­3 fatty acids
  5. 5. Statins may extend lives by not only lowering cholesterol levels but also protecting against telomere shortening, thus reducing the risk of cardiovascular disease and other age­associated diseases A) All individuals B) Individuals on pravastatin treatment (grey) or placebo (orange)  

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