Overview
 Tersus Pharmaceuticals
 Provinal® Purified Omega
7
 Scientific Overview
 The Business Opportunity
 Regulato...
Tersus Pharmaceuticals
 Founded in 2009
 In 2010, Tersus was recipient of “Affordable
Care Act Grants to Support Groundb...
The high cost of poor health
 Chronic disease has overtaken
infectious disease as #1 threat
globally
 1 of 2 people die ...
Provinal® - Scientific Overview
 The Cleveland Clinic Study
Purifying Palmitoleic Acid
 Palmitoleic Acid (C16:1n7)
 Macadamia Nuts
 Sea Buckthorn
 Fish Oil
Purifying Palmitoleic Acid
 The word “napalm” is derived from the words
naphthenic acid and palmitic acid
Purifying Palmitoleic Acid
 "Design is the first
signal of human
intention” ~ William
McDonough, Cradle
to Cradle
 WHO p...
Fatty Acid Profiles: Fish Oil vs. Krill Oil
Fatty Acid Profiles: Superba vs. Provinal®
0
10
20
30
40
50
60
Active Ingredient Palmitic Acid
34.1
21.8
51.4
0.5
Superba ...
Provinal® - Business Opportunity
 CVD
 Not just
cholesterol &
triglycerides
but
inflammation
 Attacks multiple pathways...
Provinal® - Business Opportunity
0
10
20
30
40
50
60
70
Avg CRP
Reduction
Avg TG
Reduction
Avg LDL
Reduction
Avg HDL
Incre...
Provinal vs Vascepa (AMR)
Provinal® - Business Opportunity
0%
10%
20%
30%
40%
50%
60%
70%
Lovaza (4g) Algal DHA
(7.5g)
Krill Oil (3g) Vascepa (4g) P...
Provinal® - Summary of Benefits
 Lowers C-reactive protein ("CRP" -
which measures inflammation in the
body)
 Lowers tri...
The Business Opportunity: “5 areas in
arterial aging YOU can impact”
1. Endothelial & Grout Injury/dysfunction
2. Quality ...
5 areas in arterial aging YOU can
impact with Aspirin:
1. Endothelial & Grout Injury/dysfunction
2. Quality of LDL Repair
...
5 areas in arterial aging YOU can
impact with Aspirin & Omega 7:
1. Endothelial & Grout Injury/dysfunction
2. Quality of L...
Provinal® - Regulatory Situation
 GRAS Certified by AIBMR
 Structure Function Claims
 Helps maintain normal triglycerid...
Provinal® - Time to Market
 The raw materials required to
produce Provinal® are:
 abundant,
 sustainable, and
 scalabl...
Purified Omega 7, The Next Omega
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Purified Omega 7, The Next Omega

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Purified Omega 7 Palmitoleic Acid is a "Medical Breakthrough" that is clinically shown to reduce C-Reactive Protein (CRP), and prevent the buildup of atherosclerotic plaque by optimizing cholesterol and reducing inflammation in the arteries.

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Purified Omega 7, The Next Omega

  1. 1. Overview  Tersus Pharmaceuticals  Provinal® Purified Omega 7  Scientific Overview  The Business Opportunity  Regulatory Situation  Timeline to Market
  2. 2. Tersus Pharmaceuticals  Founded in 2009  In 2010, Tersus was recipient of “Affordable Care Act Grants to Support Groundbreaking Biomedical Research”  In 2011, conducted research, launched Provinal®, and built a global and scalable supply chain  In 2012, launched several products, conducted more research, and Dr. Michael F. Roizen became Chairman of Scientific Advisory Board
  3. 3. The high cost of poor health  Chronic disease has overtaken infectious disease as #1 threat globally  1 of 2 people die of heart attack or stroke and never knew what hit them  More than $1 trillion wasted annually in the U.S. alone (as well as loss of life and productivity)
  4. 4. Provinal® - Scientific Overview  The Cleveland Clinic Study
  5. 5. Purifying Palmitoleic Acid  Palmitoleic Acid (C16:1n7)  Macadamia Nuts  Sea Buckthorn  Fish Oil
  6. 6. Purifying Palmitoleic Acid  The word “napalm” is derived from the words naphthenic acid and palmitic acid
  7. 7. Purifying Palmitoleic Acid  "Design is the first signal of human intention” ~ William McDonough, Cradle to Cradle  WHO places palmitic acid in the same category of cardiovascular risk as transfat: “How much transfat would you like in your supplement?” Source: World Health Organization
  8. 8. Fatty Acid Profiles: Fish Oil vs. Krill Oil
  9. 9. Fatty Acid Profiles: Superba vs. Provinal® 0 10 20 30 40 50 60 Active Ingredient Palmitic Acid 34.1 21.8 51.4 0.5 Superba (o-3) Provinal (o-7)
  10. 10. Provinal® - Business Opportunity  CVD  Not just cholesterol & triglycerides but inflammation  Attacks multiple pathways to combat: Atherosclerosis, Diabetes, Metabolic Syndrome, Fatty Liver
  11. 11. Provinal® - Business Opportunity 0 10 20 30 40 50 60 70 Avg CRP Reduction Avg TG Reduction Avg LDL Reduction Avg HDL Increase 67 36 10.3 4.2 Omega 7 Clinical Trial % Change for 16 Subjects in one month taking 210 mg/day A clinical trial was conducted by Dr. Luis Martinez at the Xyrion Physician Training and Specialty Clinic in Puerto Rico. Dr. Martinez is a Board Certified Lipidologist, Anti- Aging and Regenerative Medicine Specialist, residency trained in Preventive, Occupational, and Environmental Medicine. This small clinical – a pre- curser to a larger 54 person, double-blind, placebo controlled experiment.
  12. 12. Provinal vs Vascepa (AMR)
  13. 13. Provinal® - Business Opportunity 0% 10% 20% 30% 40% 50% 60% 70% Lovaza (4g) Algal DHA (7.5g) Krill Oil (3g) Vascepa (4g) Palmitoleic Acid (210mg) 1% 15% 17% 22% 67% Comparison to Omega 3 Products Avg Reduction CRP in one month
  14. 14. Provinal® - Summary of Benefits  Lowers C-reactive protein ("CRP" - which measures inflammation in the body)  Lowers trigylcerides and hepatic fat accumulation,  Lowers bad cholesterol, and  Increases good cholesterol.
  15. 15. The Business Opportunity: “5 areas in arterial aging YOU can impact” 1. Endothelial & Grout Injury/dysfunction 2. Quality of LDL Repair 3. Chronic Inflammation 4. Acute Inflammation/Rupture 5. Platelet/Clot Aggregation on injury ~ Dr. Michael F. Roizen, MD
  16. 16. 5 areas in arterial aging YOU can impact with Aspirin: 1. Endothelial & Grout Injury/dysfunction 2. Quality of LDL Repair 3. Chronic Inflammation 4. Acute Inflammation/Rupture 5. Platelet/Clot Aggregation on injury ~ Dr. Michael F. Roizen, MD
  17. 17. 5 areas in arterial aging YOU can impact with Aspirin & Omega 7: 1. Endothelial & Grout Injury/dysfunction 2. Quality of LDL Repair 3. Chronic Inflammation 4. Acute Inflammation/Rupture 5. Platelet/Clot Aggregation on injury ~ Dr. Michael F. Roizen, MD
  18. 18. Provinal® - Regulatory Situation  GRAS Certified by AIBMR  Structure Function Claims  Helps maintain normal triglycerides *  Helps maintain normal C-reactive protein (CRP) levels *
  19. 19. Provinal® - Time to Market  The raw materials required to produce Provinal® are:  abundant,  sustainable, and  scalable – and the company has secured a global supply.

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