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ISSN 1749-3889 (print), 1749-3897 (online)
                                                                                     International Journal of Nonlinear Science
                                                                                                     Vol.xx(20x) No.xx,pp.??-??


           Global asymptotic dynamics of a host-vector model with two delays
                              Cruz Vargas-De-Le´ n1
                                               o               2 ∗
                                                                     , Guillermo G´ mez-Alcaraz2
                                                                                  o
     1
         Unidad Acad´ mica de Matem´ ticas,Universidad Aut´ noma de Guerrero, Chilpancingo, Guerrero, M´ xico
                     e                a                     o                                           e
               2
                 Facultad de Ciencias, Universidad Nacional Aut´ noma de M´ xico M´ xico, D.F., M´ xico
                                                               o          e       e              e
                                         (Received xx , accepted xx, will be set by the editor)

     Abstract: Host-vector disease models with discrete time delays or distributed time delays are studied. By
     means of Lyapunov’s direct method, we establish the global stability conditions of the equilibrium states. We
     proved that the global stability are completely determined by the threshold parameter, R0 . If the threshold
     parameter is less than or equal to unity, the disease-free equilibrium state is globally asymptotically stable
     for any time delays in the feasible region. If the threshold parameters greater than one, a unique endemic
     equilibrium state exists and is globally asymptotically stable for any time delays in the interior of the feasible
     region. We extended our analysis to sexually-transmitted diseases models.

     Keywords: host-vector model; distributed time-delay; discrete time-delay; global asymptotic stability; method
     of Lyapunov functionals.


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                                        Copyright c World Academic Press, World Academic Union
                                                          IJNS.20xx.xx.xx/xx
2                                                            International Journal of NonlinearScience,Vol.xx(20xx),No.xx,pp. ??-??


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                                     IJNS email for contribution: editor@nonlinearscience.org.uk

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Global asymptotic dynamics of a host-vector model with two delays

  • 1. ISSN 1749-3889 (print), 1749-3897 (online) International Journal of Nonlinear Science Vol.xx(20x) No.xx,pp.??-?? Global asymptotic dynamics of a host-vector model with two delays Cruz Vargas-De-Le´ n1 o 2 ∗ , Guillermo G´ mez-Alcaraz2 o 1 Unidad Acad´ mica de Matem´ ticas,Universidad Aut´ noma de Guerrero, Chilpancingo, Guerrero, M´ xico e a o e 2 Facultad de Ciencias, Universidad Nacional Aut´ noma de M´ xico M´ xico, D.F., M´ xico o e e e (Received xx , accepted xx, will be set by the editor) Abstract: Host-vector disease models with discrete time delays or distributed time delays are studied. By means of Lyapunov’s direct method, we establish the global stability conditions of the equilibrium states. We proved that the global stability are completely determined by the threshold parameter, R0 . If the threshold parameter is less than or equal to unity, the disease-free equilibrium state is globally asymptotically stable for any time delays in the feasible region. If the threshold parameters greater than one, a unique endemic equilibrium state exists and is globally asymptotically stable for any time delays in the interior of the feasible region. We extended our analysis to sexually-transmitted diseases models. Keywords: host-vector model; distributed time-delay; discrete time-delay; global asymptotic stability; method of Lyapunov functionals. References [] E. Beretta and Y. Takeuchi Global stability of an SIR epidemic model with time delays. J Math. Biol., 33 (1995) 250–260. [] C. Bowman, A. B. Gumel, P. van den Driessche. J. Wu, H. Zhu, A mathematical model for assessing control strategies against West Nile virus. Bull. Math. Biol., 67 (2005) 1107–1133. [] G. Cruz-Pacheco, L. Esteva, J. A. Montao-Hirosec, C. Vargas. Modelling the dynamics of West Nile Virus. Bull. Math. Biol., 67 (2005) 1157-1172. [] E. Beretta and V. Capasso. On the general structure of epidemic systems. Global asymptotic stability. Comput. Math. Appl., Part A, 12 (1986), 677–694. [] K. L. Cooke. Stability analysis for a vector disease model. Rocky Mount. J. Math., 9 (1979) 31–42. [] K. Dietz. Transmission and control of arbovirus diseases in: D. Ludwig et al. (Eds.), Epidemiology, Proceedings of the Society for Industrial and Applied Mathematics. Philadelphia, PA. 1974. [] L. E. Elzgolts and S. B. Norkin. “Introduction to the Theory of Differential Equations with Deviating Argument.” Academic Press, New York. 1973. [] L. Esteva, C. Vargas. Analysis of a Dengue disease transmission model. Math. Biosci., 150 (1998) 131–151. [] L. Esteva, C. Vargas. A model for dengue disease with variable human population. J. Math. Biol., 38 (1999) 220–240. [] L. Esteva, A.B. Gumel and C. Vargas-De-Le´ n. Qualitative study of transmission dynamics of antibiotic-resistant o malaria. Math. Comp. Modell. 50 (2009) 611–630. [] Z. Feng, J. X. Velasco-Hern´ ndez. Competitive exclusion in a vector-host model for dengue fever. J. Math. Biol., 35 a (1997) 523–544. [] B. S. Goh. Global stability in two species interactions. J. Math. Biol., 3 (1976) 313–318. [] N. G. Gratz. Emerging and resurging vector-borne diseases. Annu. Rev. Entomol., 44 (1999) 51–75. [] D. J. Gubler. Resurgent vector-borne diseases as a global health problem. Emerg. Infect. Dis., 4 (1998) 442–450. [] H. Guo, M. Y. Li and Z. Shuai. Global stability of the endemic equilibrium of multigroup SIR epidemic models. Can. Appl. Math. Q., 14 (2006) 259-284. ∗ Corresponding author. E-mail address: leoncruz82@yahoo.com.mx Copyright c World Academic Press, World Academic Union IJNS.20xx.xx.xx/xx
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