Upconversion nanoparticles are a unique range of fluorescent nanoparticles. The upconversion luminescence
arises from a phenomenon whereby light of low energy, usually in the NIR wavelength, is converted to
light of higher energy in the shorter wavelength. The use of NIR light as the excitation source has various
advantages such as high tissue penetration depth, nil background autofluorescence, low photo-toxicity and
excellent detection sensitivity. These nanoparticles act as a platform technology and can be used in a variety of
applications such as imaging, food testing, environmental testing, veterinary testing, in-vitro diagnostics, anticounterfeiting,
optogenetics and cancer therapy. This technology has been well patented and various studies
have been published in top ranking journals such as Nature Medicine, Nature Protocols and PNAS.