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CSF Analysis

CEREBRO SPINAL FLUID

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CSF Analysis

  1. 1. LUMBAR PUNCTURE & CSF ANALYSIS KEERTHI PRIYA, MPT NEURO ASSISTANT PROFESSOR 11-06-2020 1
  2. 2. LUMBAR PUNCTURE 11-06-2020 2
  3. 3. WHAT IS LUMBAR PUNCTURE? 11-06-2020 3
  4. 4. INTRODUCTION A diagnostic procedure which is used to collect CSF to rule out infectious & non-infectious neurological conditions. It’s also a therapeutic procedure. Uses : Spinal anaesthesia Administration of chemotherapy & antibiotics To drain CSF Introducing contrast medium for Myelography & Cisternography 11-06-2020 4
  5. 5. STEPS INVOLVED IN LUMBAR PUNCTURE  Persons Equipment Position Site Procedure 11-06-2020 5
  6. 6. Equipment  Glove  Iodine  Sponge  Drapes  Lidocaine  Syringe  Needle  3 way stop cock  Manometer  Collection tubes  Adhesive bandage 11-06-2020 6
  7. 7. Position & Site Site : L3-L4/L4-L5 11-06-2020 7
  8. 8. Procedure 11-06-2020 8
  9. 9. COMPLICATIONS MAJOR Herniation Injury To Cord & Nerve Roots Spinal Hematoma Infection Deterioration of conscious MINOR Back Ache POST LP Pain Radicular Pain/ Numbness Neck stiffness Dilated pupils 11-06-2020 9
  10. 10. CSF ANALYSIS 11-06-2020 10
  11. 11. CSF FORMATION & CIRCULATION 11-06-2020 11
  12. 12. FUNCTIONS  Protection Supplies nutrients Removal of waste products Transportation 11-06-2020 12
  13. 13. INDICATIONS  Infection Inflammatory Disease Subarachnoid haemorrhage Hepatic encephalopathy Meningeal malignancies Paraneoplastic abnormalities ICP abnormalities 11-06-2020 13
  14. 14. CONTRA INDICATIONS  Intracranial Mass Lesion Local Infection Coagulopathy Spinal Cord Mass Lesion 11-06-2020 14
  15. 15. NORMAL VALUES  5 Mononuclear Leukocytes  NO Polymorphoneuclear cells No Erythrocytes Volume: 150 ml 11-06-2020 15
  16. 16. NORMAL PHYSICAL EXAMINATION CONTENTS COLOUR COLOUR LESS VISCOCITY NON VISCOUS APPEARANCE CLEAR PH 7.28-7.32 SPECIFIC GRAVITY 1.006-1.007 PRESSURE 180-200mm of H2O 11-06-2020 16
  17. 17. NORMAL BIO CHEMICAL VALUES CONTENTS VALUES GLUCOSE 2.22-3.89 mmol/L LACTATE 1-2 mmol/L PROTIEN 6-50 mg/L ALBUMIN 6.6-44.2 mg/L IgG 0.9-5.7mg/L CHOLESTEROL 0.2-0.6 mg/dL AMONIA 25-80 micrograms/L 11-06-2020 17
  18. 18. NORMAL BIO CHEMICAL VALUES CONTENTS VALUES SODIUM 135-180mEq/L POTASSIUM 2.6-3 mEq/L CHLORINE 115-130 mEq/L CSF GLUCOSE/PLASMA GLUCOSE 0.6-0.7 11-06-2020 18
  19. 19. ANALYSIS OF RESULTS 11-06-2020 19
  20. 20. APPEARANCE  Normal: Colour Less Bilirubin: Yellow Erythrocytes: Red Melanin: Black 11-06-2020 20
  21. 21. CELL COUNT Normal =5 Mononuclear leucocytes Increases : Meningitis Infections Seizures Infarct Degeneration & inflammatory conditions 11-06-2020 21
  22. 22. PROTIEN  Meningitis  Hemorrhage  Endocrine  Neurosyphilis  Multiple Sclerosis  CVD 11-06-2020 22
  23. 23. VISCOCITY Increases : Meningitis Cryptococcal Meningitis Adenocarcinoma 11-06-2020 23
  24. 24. CLOT FORMATION Meningitis Increased Proteins T.B Meningitis 11-06-2020 24
  25. 25. 11-06-2020 25
  26. 26. 11-06-2020 26
  27. 27. 11-06-2020 27
  28. 28. THANK YOU 11-06-2020 28

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