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Specific defense

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Specific defense

  1. 1. Specific Defense (pg 8)
  2. 2. Specific Defense (pg 8)• Third line of defense• Results in immunity
  3. 3. Specific Defense (pg 8)• Third line of defense• Results in immunityCharacteristics:1. Specific: recognizes and acts againstparticular pathogens
  4. 4. Specific Defense (pg 8)• Third line of defense• Results in immunityCharacteristics:1. Specific: recognizes and acts againstparticular pathogens2. Systemic: immunity is not restricted to theinitial infection site
  5. 5. Specific Defense (pg 8)• Third line of defense• Results in immunity• Characteristics:1. Specific: recognizes and acts againstparticular pathogens2. Systemic: immunity is not restricted to theinitial infection site3. Memory: Mounts an even stronger attack onpathogens that have been previouslyencountered
  6. 6. Definitions• Antigen: molecules that are recognized asforeign by the body. Bacteria and otherpathogens bear such foreign molecules onthe surface of their cells.
  7. 7. Definitions• Antigen: molecules that are recognized asforeign by the body. Bacteria and otherpathogens bear such foreign molecules onthe surface of their cells.• Antibody: Y-shaped proteins produced bythe body. Each antibody attacks only oneparticular antigen and disables it. “Predatordrones”
  8. 8. Types of Lymphocytes• All lymphocytes are made in the bonemarrow, but they go to different places tobecome immunocompetent (capable ofresponding to a specific antigen)
  9. 9. Types of Lymphocytes• All lymphocytes are made in the bonemarrow, but they go to different places tobecome immunocompetent (capable ofresponding to a specific antigen)• T-lymphocytes (70%): mature in the thymus.Involved in cell-mediated immunity, where t-lymphocytes directly attack antigens. Mosteffective against virus-infected cells, cancercells, foreign tissue, fungi, protozoans
  10. 10. Types of Lymphocytes• T-lymphocytes (70%): mature in the thymus.Involved in cell-mediated immunity, where t-lymphocytes directly attack antigens. Mosteffective against virus-infected cells, cancercells, foreign tissue, fungi, protozoans• B-lymphocytes (30%): mature in the bonemarrow. Involved in antibody-mediatedimmunity. B-lymphocytes don’t attackdirectly, but produce antibodies that bind tothe antigen and inactivate it. Most effectiveagainst bacteria, viruses outside of cells, andtoxins
  11. 11. Output (pg 9)• Paste in Antibody-mediated and Cell-mediatedimmunity diagrams
  12. 12. Acquired Immunity (pg 10)
  13. 13. Acquired Immunity (pg 10)• Active: Individual’s own body producesmemory T-cells and B-cells
  14. 14. Acquired Immunity (pg 10)• Active: Individual’s own body producesmemory T-cells and B-cells• Passive: Immune agents are made in someoneelse’s body and then transferred to theindividual
  15. 15. Acquired Immunity (pg 10)1. Active natural: Contract a disease andproduce memory cells
  16. 16. Acquired Immunity (pg 10)1. Active natural: Contract a disease andproduce memory cells2. Active artificial: receive a vaccination andproduce memory cells
  17. 17. Acquired Immunity (pg 10)1. Active natural: Contract a disease andproduce memory cells2. Active artificial: receive a vaccination andproduce memory cells3. Passive natural: baby receive maternalantibodies through placenta or breast milk
  18. 18. Acquired Immunity (pg 10)1. Active natural: Contract a disease andproduce memory cells2. Active artificial: receive a vaccination andproduce memory cells3. Passive natural: baby receive maternalantibodies through placenta or breast milk4. Passive artificial: receive antiserum thatcontains antibodies produced in anotherhost. Used to treat rabies, botulism, bitesfrom venomous snakes and spiders

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