2. You‘ll find out…
• What stem cells actually are.
• Which talents they have.
• Why you need them.
• How to become a millionaire.
• The last point was a lie (or not).

3. Stem cells  ancient tribe?
• are concerning each higher organism
• are „building stones“
• 1st stem cell  fertilized ovum
•  foundation for the whole organism
• via multiplication & differentiation of stem cells
•  >200 different cell types
• formation of all tissues & organs

5. Have you ever met a stem cell?
• 2 defining capabilities to know it‘s a stem cell indeed
1 Specialization
• after divison  secondary cell specialized
• „choose if they want to be“ a neuron, blood- ,bone-,.. cell
• stem cells are universal cells
•  not originally made as a certain type of cell
• fulfill important regeneration & reparation functions

6. Have you ever met a stem cell?
• 2 defining capabilities to know it‘s a stem cell indeed
• by replication
•  replacement is like a copy
•  same properties
2 Self-Renewal

7. How can they help us?
• regenerative & general medicine
• drug development
• therapeutic use
• disease modelling

8. Stem cell = stem cell?
• differentiate 2 central forms
•  concerning their origin
1 Embryonic Stem Cells (ESCs)
• „mothers of all cells“
• can turn into any specific type of cell
• struggles:
• exist only for a short period of time
• medical use is ethically controversial

9. Stem cell = stem cell?
• differentiate 2 central forms
2 Adult Stem Cells
• „knights in shining armour“
• create substitutes
• ensure to fix/replace destroyed cells
• cannot differentiate into all types of cells
• struggles:
• obtaining  difficult, risky & expensive

10. Toti- pluri- what?!
• distinguish them by their potency
• can differentiate into any kind of cell
• are able to give rise to an entirely functional organism
• example: fertilized ovums
1 Totipotent Stem Cells

11. 2 Pluripotent Stem Cells
Toti- pluri- what?!
• distinguish them by their potency
• are similar to totipotent stem cells
• can differentiate into any kind of cells
• are able to give rise to all tissue types
•  but not to an entire organism
• example: embryonic stem cells

12. Toti- pluri- what?!
• distinguish them by their potency
• can differentiate into different cell types within a tissue type
• example: adult stem cells
3 Multipotent Stem Cells

13. Research amazing – stem cells amazing
Induced Pluripotent Stem Cells (iPSCs)
• are synthesized
• by adding gens to ordinary tissue cells
•  leads to „reprogramming“
• manmade qualities  similiar to embryonic stem cells
• medical use  lesser ethical issue

14. Research amazing – stem cells amazing
Induced Pluripotent Stem Cells (iPSCs)
• may be produced corresponding to a patient´s needs
• Problem of immune rejection solved?
• possibility to differentiate them into neurons
• huge potential in medical use

15. Multitalents  heal, help & hypnotize
• Just kidding, but who knows what research may find out?
• stem cells can replace damaged cells
• are used after heart attacks, burns, spinal cord injuries, strokes, …
1 Regenerative Medicine

16. Multitalents  heal, help & hypnotize
• Just kidding, but who knows what research may find out?
• used to create organs & tissues
• huge potential in medicine
2 Synthesis

17. Multitalents  heal, help & hypnotize
• Just kidding, but who knows what research may find out?
• used to develop medicine
• prevent side effects
• reduce animal testing
3 Drug Development

18. Multitalents  heal, help & hypnotize
• Just kidding, but who knows what research may find out?
• used to model disease mechanisms
• in order to better understand illnesses
• to improve healing chances
4 Disease Modelling

20. How do we know?
We just asked them 
• https://www.vita34.at/stammzellen/
• https://de.wikipedia.org/wiki/Stammzelle
• http://www.planet-wissen.de/natur/forschung/stammzellen_die_alleskoenner_unter_den_zellen/
• http://flexikon.doccheck.com/de/Stammzelle
• http://www.oeaw.ac.at/oesterreichische-akademie-der-wissenschaften/die-oeaw/article/stammzellen-ersatzteile-aus-dem-labor/
• http://www.forumgesundheit.at/portal27/forumgesundheitportal/content?contentid=10007.757033&viewmode=content&portal:componentId=gtnd
dbb3089-5ab1-4bb1-b4b8-5b4d46e787b6
• http://www.imabe.org/index.php?id=1737
• http://www.wissensschau.de/stammzellen/ips_zellen.php
• https://de.wikipedia.org/wiki/Induzierte_pluripotente_Stammzelle
• https://www.welt.de/wissenschaft/article123838643/Stammzellen-helfen-bei-Arzneimittel-Entwicklung.html
• http://www.wissensschau.de/stammzellen/embryonale_stammzellen.php
• http://www.zellwerk.biz/serv_stemc.htm
• http://www.ivf.at/BEHANDLUNG/K%C3%BCnstlicheBefruchtung.aspx
• Drawings: Google Autodraw_by Isabell Aigner
• http://www.planet-wissen.de/natur/forschung/stammzellen_die_alleskoenner_unter_den_zellen/mitstammzellenneuewirkstoffeerforschen100~_v-
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