2. Medical English
Dr. Rosa Gonzales
Calderon Baldera Karen Eliana
Diaz Mino Marlon Werner
Fernandez Ferreyra Ana Maria Sofia
Niño Effio Brenda Stefanny
Popuche Cabrera Pedro Luis
Razuri Farro Juan Alessandro
5. Hematopoietic Stem Cell Pediatric Transplatation
standard procedure
treatment of hematological diseases
of
in solid tumors
infusion
Reconstitution of hematopoiesis
treatment of multiple malignancies in children.
6. Hematopoietic Stem Cell Pediatric Transplatation
The infusion of hematopoietic progenitors
cells from the patient in cases of
secondary myelosuppression
administration of high dose chemotherapy
known as
AUTOLOGOUS OR
AUTOLOGOUS TRANSPLANTATION
7. Hematopoietic Stem Cell Pediatric Transplatation
This procedure is used for the
treatment of some high-risk tumors
in childhood:
Neuroblastoma Ewing sarcoma
Medulloblastoma Nephroblastoma
8. Hematopoietic Stem Cell Pediatric Transplatation
Its use as consolidation treatment
in acute myeloid leukemia is
discussed.
In the case of lymphoblastic leukemia,
their use is more controversial.
9. Hematopoietic Stem Cell Pediatric Transplatation
UNRELATED DONORS (UNRELATED) RESTRICTED USE
SHOULD BE DISCUSSED ON THE
BASIS OF INDIVIDUAL CASES
10. Hematopoietic Stem Cell Pediatric Transplatation
However… IN RECENT YEARS
The results obtained with unrelated donor
Is approaching those obtained
with donor family
11. Hematopoietic Stem Cell Pediatric Transplatation
So the use of unrelated donors
is spreading and expanding indications.
12. Hematopoietic Stem Cell Pediatric Transplatation
Initially, hematopoietic progenitors were
obtained from bone marrow
in a surgical procedure involving the
direct puncture of the same
13. Hematopoietic Stem Cell Pediatric Transplatation
In the nineties saw the widespread use of
hematopoietic progenitors derived from
peripheral blood
This procedure consisted in
administering drugs able to raise the
number of progenitors in the circulating
blood, to be removed later by
leukapheresis.
14. Hematopoietic Stem Cell Pediatric Transplatation
although with
Such parents get faster hematopoietic
higher
recovery than those obtained from
incidence of
bone marrow
chronic GVHD.
15. Hematopoietic Stem Cell Pediatric Transplatation
Finally in Pediatrics Units
increasing
Use Progenitors Cells
from
Umbilical Cord Blood
16. Hematopoietic Stem Cell Pediatric Transplatation
These progenitors cells
have
A Slower Recovery of Lower Incidence of
but
Hematopoetic Function Disease
17. Hematopoietic Stem Cell Pediatric Transplatation
In the future
Two important proteins
Noggin Chordin
They have a better proliferation function
Many scientists say talk of a possible cure of pediatric cancer