Cosmetic Products Analysis of Trends Through Knowledge Engineering Techniques

1. Cosmetic Products Analysis of Trends Through Knowledge Engineering Techniques Rafael Bailón Moreno1 Rosario Ruiz-Baños1 José Pino-Díaz2 Laila Chiadmi-García1 Francisco Félix Maldonado-Calvache1 (1) Universidad de Granada (2) Universidad de Málaga

2. Summary THROUGH KNOWLEDGE ENGINEERING TECHNIQUES COSMETIC PRODUCTS: ANALYSIS OF TRENDS  Introduction  Methodology  Co-word Analysis  Strategic and structural analysis  Dynamic analysis or trend analysis  Corpus documental  Knowledge System Results and Analysis  Production  Centres of interest: research themes  Strategic diagrams and centres of interest CED 2013 leaders  Trend analysis  Conclusions

3. Introduction THROUGH KNOWLEDGE ENGINEERING TECHNIQUES COSMETIC PRODUCTS: ANALYSIS OF TRENDS Data and information technoscientific are so superabundant that even experts in a technical field are not able to read and know… The speed in the development of new materials and products, new applications and technologies, and trends are changing so fast that the imperative need of "to be well informed" but without "Irrelevant information overload " is critical CED 2013

4. THROUGH KNOWLEDGE ENGINEERING TECHNIQUES Introduction Knowledge engineering is a recently developed discipline that can process massive amounts of COSMETIC PRODUCTS: ANALYSIS OF TRENDS information to convert them to positive knowledge. The positive knowledge is knowledge about a given subject that allows decisions correctly founded. The Scientific and Technological Surveillance is one activity carried out product engineer-and in general by all persons required to make decisions in the scientific, CED 2013 technological or management for know the latest news and trends related to your technoscientific field or to the type of products developed

5. THROUGH KNOWLEDGE ENGINEERING TECHNIQUES COSMETIC PRODUCTS: ANALYSIS OF TRENDS Introduction The purpose of this study is highlighting the latest trends in the scientific and technological development of new cosmetic products using knowledge engineering tools CED 2013

6. Methodology THROUGH KNOWLEDGE ENGINEERING TECHNIQUES COSMETIC PRODUCTS: ANALYSIS OF TRENDS  Introduction  Methodology  Co-word Analysis  Strategic and structural analysis  Dynamic analysis or trend analysis  Corpus documental  Knowledge System Results and Analysis  Production  Centres of interest: research themes  Strategic diagrams and centres of interest CED 2013 leaders  Trend analysis  Conclusions

7. Methodology Co-word Analysis THROUGH KNOWLEDGE ENGINEERING TECHNIQUES COSMETIC PRODUCTS: ANALYSIS OF TRENDS Co-word analysis is a method used in knowledge discovery in bibliographic databases. Two actors, i.e. two words, two concepts, two researchers, are interrelated when frequently appear in the same documents. At the same time, these two actors are associated with others different actors and so on to form a large technoscientific network. 2 The strength of the bond between two words i and j (or cij other actors) is quantified with the equivalence index: eij  CED 2013 ci c j When all words of all documents are compared an adjacency matrix is obtained. This matrix represents the network of actors.

8. Methodology Co-word Analysis THROUGH KNOWLEDGE ENGINEERING TECHNIQUES COSMETIC PRODUCTS: ANALYSIS OF TRENDS Within the technoscientific network there are areas where the density of links around some nodes is greater than in the rest of the network. These areas consist on very connected nodes that are called centres of interest, because they represent sets of relationships specially developed. CED 2013

9. Methodology Strategic and structural analysis THROUGH KNOWLEDGE ENGINEERING TECHNIQUES COSMETIC PRODUCTS: ANALYSIS OF TRENDS When actors are words or concepts, the interest centres represent the research topics or research themes that are relevant in the network of actors. 1) Density: Represents the average intensity of the links of a theme. 2) Centrality: Represents how close to the centre of the network is the theme. It is measured by the number of links of CED 2013 this topic to rest of technoscientific network.

10. Methodology Dynamic analysis or trend analysis THROUGH KNOWLEDGE ENGINEERING TECHNIQUES COSMETIC PRODUCTS: ANALYSIS OF TRENDS Research topics are redefined in the course of time, the words of the themes are modified according research progresses and new Therefore, a careful analysis discoveries are being imposed. of the words that disappear Density and appear in the topics and Actor their evolution within the (at year 2013) strategic diagram, will explain Actor what might be the future (at year 2019?) scenario of the techno- Centrality scientific research in the field that is being considered. Actor Actor (at year 2007) CED 2013 (at year 2001)

11. Methodology Corpus documental THROUGH KNOWLEDGE ENGINEERING TECHNIQUES COSMETIC PRODUCTS: ANALYSIS OF TRENDS Bibliographic database: Scopus Time period: 2001-2012 Interrogation: TITLE-ABS-KEY (cosmetic * product *) AND PUBYEAR> 2000 AND PUBYEAR <2013> Four sub-periods of three years each: 2001-2003, CED 2013 2004-2006, 2007-2009, 20010-2012 Number of documents: 7621

12. Methodology Knowledge System THROUGH KNOWLEDGE ENGINEERING TECHNIQUES COSMETIC PRODUCTS: ANALYSIS OF TRENDS Techné Coword 1.0 Software developed by the research group Techné, Knoeledge CED 2013 and Product Engineering

13. Results and Analysis THROUGH KNOWLEDGE ENGINEERING TECHNIQUES COSMETIC PRODUCTS: ANALYSIS OF TRENDS  Introduction  Methodology  Co-word Analysis  Strategic and structural analysis  Dynamic analysis or trend analysis  Corpus documental  Knowledge System Results and Analysis  Production  Centres of interest: research themes  Strategic diagrams and centres of interest CED 2013 leaders  Trend analysis  Conclusions

14. Results and Analysis Production THROUGH KNOWLEDGE ENGINEERING TECHNIQUES COSMETIC PRODUCTS: ANALYSIS OF TRENDS The number of papers published each year on cosmetics increases linearly CED 2013 The number accumulated of published documents grows quadratically

15. Results and Analysis Production: Institution and Company THROUGH KNOWLEDGE ENGINEERING TECHNIQUES COSMETIC PRODUCTS: ANALYSIS OF TRENDS Doc. Institution/Company Doc. Institution/Company 92 Universidade de Sao Paulo 25 The University of British Columbia 71 Procter and Gamble 25 University of California, San Francisco 59 Food and Drug Administration 25 University of Miami 54 L'Oreal 23 Johnson & Johnson 45 Universidade Estadual de Campinas 22 Cheju National University 41 Unilever 22 Henkel KGaA 40 Research Institute for Fragrance Materials, Inc. 22 Istituto Superiore Di Sanita, Rome 39 Københavns Universitet 21 Alma Mater Studiorum Università di Bologna 39 Universität Göttingen 21 Bundesinstitut für Risikobewertung 36 Charite - Universitätsmedizin Berlin 21 Seoul National University 33 Beiersdorf AG 21 Università degli Studi di Firenze 33 Universität Erlangen-Nürnberg 21 University of Ferrara 32 Odense Universitetshospital 21 University of Massachusetts Amherst 32 Universidad de Santiago de Compostela 21 University of Toronto 32 Università degli Studi di Napoli Federico 20 Amtssygehuset i Gentofte CED 2013 32 Universitat de Valencia 20 Freie Universität Berlin(20) 30 European Commission Joint Research Centre 20 Università degli Studi di Roma La Sapienza 27 Katholieke Universiteit Leuven 20 Universiti Putra Malaysia 27 UNESP-Universidade Estadual Paulista 20 University of California, San Diego 26 Universidade Federal do Rio de Janeiro

16. Results and Analysis Centres of interest: research themes THROUGH KNOWLEDGE ENGINEERING TECHNIQUES COSMETIC PRODUCTS: ANALYSIS OF TRENDS The number of centres of interest or research topics identified by Techné Coword knowledge system increases with time Research topics are more and more diverse because the CED 2013 cosmetics market is more and more competitive

17. Results and Analysis Strategic diagram: Period 2001-2003 THROUGH KNOWLEDGE ENGINEERING TECHNIQUES COSMETIC PRODUCTS: ANALYSIS OF TRENDS CED 2013 • 1 TOXICITY-TESTING: TOXICITY-TESTS, CONSUMER-PRODUCT-SAFETY, SKIN-IRRITATION, GENOTOXICITY, ANIMAL-EXPERIMENT • 2 FEMALE: ADULT, MALE, MIDDLE-AGED, ADOLESCENT, CONTROLLED-STUDY, DERMATITIS,- ALLERGIC-CONTACT

18. COSMETIC PRODUCTS: ANALYSIS OF TRENDS THROUGH KNOWLEDGE ENGINEERING TECHNIQUES CED 2013 Strategic diagram: Period 2004-2006 Results and Analysis

19. Results and Analysis Strategic diagram: Period 2004-2006 THROUGH KNOWLEDGE ENGINEERING TECHNIQUES COSMETIC PRODUCTS: ANALYSIS OF TRENDS • 1 ADULT: FEMALE, MIDDLE-AGED, MALE, AGED, ADOLESCENT, CONTROLLED-STUDY, CONTROLLED- CLINICAL-TRIAL, etc. (similar to theme 2 of period 1) • 2 ANIMALS: TOXICITY-TESTS, GENOTOXICITY, REPRODUCTIVE- TOXICITY, MUTAGENICITY, CONSUMER-PRODUCT-SAFETY, etc. (similar to theme 1 of period 1) • 5 DERMATITIS-ALLERGIC- CONTACT: ALLERGENS, ECZEMA, 2- BROMO-2- BROMOMETHYLGLUTARONITRILE, FORMALDEHYDE, PRESERVATIVES, FRAGRANCES, etc. • 4 RISK-ASSESSMENT: RISK- CED 2013 FACTORS, SKIN-IRRITATION, SKIN- TOXICITY, EYE-IRRITATION, EXPOSURE, HAIR-DYES, etc.

21. Results and Analysis Strategic diagram: Period 2007-2009 THROUGH KNOWLEDGE ENGINEERING TECHNIQUES COSMETIC PRODUCTS: ANALYSIS OF TRENDS • 2 COSMETIC-TECHNIQUES: BIOCOMPATIBLE-MATERIALS, REJUVENATION, ESTHETIC- SURGERY, FILLER, HYDROXYAPATITE, POLYLACTIC-ACID, COLLAGEN, PATIENT-SATISFACTION • 3 ADULT: FEMALE, MIDDLE-AGED, MALE, AGED, ADOLESCENT, CONTROLLED-STUDY, CONTROLLED-CLINICAL-TRIAL, etc • 5 PATCH-TESTS: DERMATITIS,- ALLERGIC-CONTACT, SKIN-ALLERGY, CONTACT-DERMATITIS, 2-BROMO- 2-BROMOMETHYL - CED 2013 GLUTARONITRILE, etc. • 9 SKIN-PIGMENTATION: HYPERPIGMENTATION, MELANOCYTES, HYDROQUINONE, KOJIC-ACID, ARBUTIN, MONOPHENOL-MONOOXYGENASE, SUNSCREEN, etc. • 11 PERFUME: SHAMPOO, SOAP, DETERGENTS, LOTION, DEODORANT-AGENT, SKIN-IRRITANCY- TESTS, etc.

24. Results and Analysis Strategic diagram: Period 2010-2012 THROUGH KNOWLEDGE ENGINEERING TECHNIQUES COSMETIC PRODUCTS: ANALYSIS OF TRENDS • 2 VAPOR-PRESSURE: TOXICOLOGICAL-PARAMETERS, SOLUBILITY, CHEMICAL-STRUCTURE, CONCENTRATION-RESPONSE, EXPOSURE, PRODUCT-SAFETY • 4 ADULT: FEMALE, MIDDLE-AGED, MALE, AGED, ADOLESCENT, CONTROLLED-STUDY, CONTROLLED- CLINICAL-TRIAL, etc • 3 WASTEWATER: EFFLUENTS, POLLUTANT-REMOVAL, WASTEWATER-RECLAMATION, WATER-TREATMENT-PLANTS, etc. • 7 ANIMALS: TOXICITY-TESTS, ANIMAL-TISSUE, ANIMAL-CELL, REPRODUCTIVE-TOXICITY, DOSE- RESPONSE-RELATIONSHIP,-DRUG, etc. • 6 DERMATITIS,-ALLERGIC-CONTACT: SKIN-ALLERGY, ALLERGENS, PRESERVATIVES,-PHARMACEUTICAL, ECZEMA, SENSITIZATION, 2-METHYL- CED 2013 4-ISOTHIAZOLIN-3-ONE, etc. • 10 HUMAN-CELL: IN-VITRO-STUDY, HUMAN-TISSUE, FIBROBLASTS, KERATINOCYTES, CELL- PROLIFERATION, APOPTOSIS, etc.

25. Results and Analysis Zoom to Carbamazepine (2010-2012): Strategic diagram THROUGH KNOWLEDGE ENGINEERING TECHNIQUES COSMETIC PRODUCTS: ANALYSIS OF TRENDS CED 2013

26. COSMETIC PRODUCTS: ANALYSIS OF TRENDS THROUGH KNOWLEDGE ENGINEERING TECHNIQUES CED 2013 Zoom to Carbamazepine (2010-2012) Results and Analysis

27. COSMETIC PRODUCTS: ANALYSIS OF TRENDS THROUGH KNOWLEDGE ENGINEERING TECHNIQUES CED 2013 Zoom to Carbamazepine (2010-2012) Results and Analysis

28. COSMETIC PRODUCTS: ANALYSIS OF TRENDS THROUGH KNOWLEDGE ENGINEERING TECHNIQUES CED 2013 Trend Analysis Results and Analysis

29. Results and Analysis Trend Analysis (DRUG PRODUCTS – CARBAMAZEPINE – THROUGH KNOWLEDGE ENGINEERING TECHNIQUES WASTEWATER) COSMETIC PRODUCTS: ANALYSIS OF TRENDS CED 2013

30. Results and Analysis Trend Analysis (ANTIOXIDANTS – ANTIOXIDANT ACTIVITY) THROUGH KNOWLEDGE ENGINEERING TECHNIQUES COSMETIC PRODUCTS: ANALYSIS OF TRENDS CED 2013

31. Results and Analysis Trend Analysis (ANTIOXIDANTS – ANTIOXIDANT ACTIVITY) THROUGH KNOWLEDGE ENGINEERING TECHNIQUES Period 2 (2004-2006) COSMETIC PRODUCTS: ANALYSIS OF TRENDS CED 2013

34. Results and Analysis Actor Analysis THROUGH KNOWLEDGE ENGINEERING TECHNIQUES COSMETIC PRODUCTS: ANALYSIS OF TRENDS For each center of interest is possible to analyze the actors involved: Companies and institutions Scientists CED 2013 Products and new developments Patents and technoscientific information

35. Conclusions THROUGH KNOWLEDGE ENGINEERING TECHNIQUES COSMETIC PRODUCTS: ANALYSIS OF TRENDS  Introduction  Methodology  Co-word Analysis  Strategic and structural analysis  Dynamic analysis or trend analysis  Corpus documental  Knowledge System Results and Analysis  Production  Centres of interest: research themes  Strategic diagrams and centres of interest CED 2013 leaders  Trend analysis  Conclusions

36. THROUGH KNOWLEDGE ENGINEERING TECHNIQUES Conclusions In the present work with the knowledge system Techné CoWord has been possible identify the main centres of interest in research on COSMETIC PRODUCTS: ANALYSIS OF TRENDS "cosmetic product" at different periods in the range 2001-20012. Furthermore, in the coming years, research and development of "cosmetic products" will be mainly focused on: 1. Analysis of water pollution of active ingredients in pharmaceuticals and personal care products, such as psychotropics, antibiotics, preservatives, and others. 2. Safety in the use of cosmetic products. 3. Study of the physicochemical and structural properties of cosmetic ingredients to evaluate their activity. That is, CED 2013 development of new Q(SAR) models. 4. The restriction of animal testing will promote new methods in- vitro and among them are those who make use of tissue engineering.

37. THROUGH KNOWLEDGE ENGINEERING TECHNIQUES Thank you very much! COSMETIC PRODUCTS: ANALYSIS OF TRENDS Rafael Bailón Moreno bailonm@ugr.es Follow us in Facebook: Techné, Knowledge CED 2013 and Product Engineering Research Group Web: http://techne-research-group.com/

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