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Hongos de interes oral, Microbiologia Oral

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Hongos de interes oral, Microbiologia Oral

  1. 1. DR. J ERNESTO SALCEDO DRA. JOSEFINA JIMENEZ
  2. 2. HONGOS DE INTERÉS ORAL
  3. 3. La mayoría de las micosis orales son producidas por las levaduras del genero Candida, especialmente C. Albicans. Se considera que 4 de cada 1,000 pacientes que van a la consulta dental general presentan síntomas de infección candidiasica. Candida albicans
  4. 4. Candida albican
  5. 5. CANDIDA ALBICANS Y OTRAS ESPECIES DEL GENERO CANDIDA. El género cándida comprende más de 150 especies de levaduras, pero el C. albicans agente implicado más frecuentemente en la candidiasis oral. Otras especies como el C. Glabrata, C. Dubliniensis, C. tropicalis, C. parasilopsis, C. Guillermondii, o C. Krusei, poseen una importancia etiológica secundaria.
  6. 6. Hongos del género candida al microscopio cuando se cultivan en un agar glucosado de Sabouraud: -Blastoconidio o levaduras (células esféricas u ovoides). -Seudomicelio (levaduras alargadas que parecen tubos). -Clamidioconidios de (forma esférica de pared gruesa).
  7. 7. PATOGENIA DE LA CANDIDIASIS ORAL Depende tanto de la alteración de los mecanismos de defensa de la persona colonizada como del potencial de factores de virulencia del hongo.
  8. 8. La cantidad y tipo de saliva Dieta PH Temperatura La presencia de algunas bacterias o prótesis dentales Tratamiento antibiótico Cortico esteroides, inmunodepresión primaria o adquirida. LOS FACTORE QUE FACILITAN LA INFECCION
  9. 9. CANDIDA ALBICANS SE CARACTERIZA POR: Virulencia: Adhesión: Producción de tubos germinales: Mecanismos de evasión de las defensas del hospedador.
  10. 10. PRESENTACION CLINICA DE LA CANDIDIASIS ORAL AGUDA: Pseudomembranosa y eritematosa. CRONICA: Pseudomembranos, eritematosa e hiperplas LESIONES ASOCIADAS: queilitis angular, estomatitis, protésica y glositis rómbica.
  11. 11. CANDIDIASIS SEUDOMEMBRANOSA AGUDA O MUGUET: Frecuente en niños y ancianos. infrecuente en personas de otras edades, solo en enfermedad grave (VIH o Leucemia). Se caracteriza por la presencia de grumos, lesiones blancas o blancoamarillentas.
  12. 12. Es muy común. complicación del tratamiento antibacteriano de amplio espectro como la tetraciclina. zonas rojizas sin la presencia de grumos o placas. Se localiza más común mente en el dorso de la lengua y paladar (imagen en espejo), dolorosa. Es más común en pacientes con VIH y pacientes con hidrocorticoides inhalados. CANDIDIASIS ERITEMATOSA AGUDA O CANDIDIASIS ATROFICA AGUDA
  13. 13. Anterior
  14. 14. Diagnostico microbiológico de la candidiasis Oral
  15. 15. TRATAMIENTO Candidiasis: la nistatina y los azoles tópicos (miconazol, econazol, clotrimazol, etc.) se utilizan más como tratamiento inicial. Candidiasis Recidivante o con VIH: Ketoconazol y los triazoles (fluconazol e itraconazol).
  16. 16. El fracaso terapéutico causas: (resistencia al antifúngico), (poblaciones fúngicas poco sensibles al antifúngico elegido). Reinfección (infección de una nueva especie fúngica o la misma luego de un tiempo). FRACASO TERAPÉUTICO
  17. 17. Fin de la Presentation

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