Components of the Nervous System Glial cells (glia)    Provide firmness and structure to the brain    Get nutrients int...
Neuron
Chemical Pathways: Neurotransmitters 7 Main neurotransmitters in the study of psychoactive drugs  Dopamine  Serotonin ...
Chemical Pathways: Neurotransmitters 1. Dopamine  Component of “reward” properties of drugs  Mood & movement  Attentio...
Chemical Pathways: Neurotransmitters 4. GABA  Sedation, drowsiness and relaxation  Depressants 5. Endorphins  Pain re...
Impact on Neurotransmission Psychoactive substances can impact neurotransmitters in  both the intoxication and withdrawal...
Chemical Theories of Behavior Variations in behavior explained through changes in brain chemistry   Historical and cultu...
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Chpt 4 part 2

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Chpt 4 part 2

  1. 1. Components of the Nervous System Glial cells (glia)  Provide firmness and structure to the brain  Get nutrients into the system  Form myelin  Create the blood-brain barrier  Initially thought to be passive in comparison to “flashy” neurons  Communicate with other glia & neurons  New frontier: play a central role in addiction and mental health issues Neurons  Analyze and transmit information  Four defined regions  Cell body  Dendrites  Axon  Presynaptic terminals  Communicate through neurotransmitters
  2. 2. Neuron
  3. 3. Chemical Pathways: Neurotransmitters 7 Main neurotransmitters in the study of psychoactive drugs  Dopamine  Serotonin  Norepinephrine  GABA  Endorphins  Glutamate  Acetylcholine
  4. 4. Chemical Pathways: Neurotransmitters 1. Dopamine  Component of “reward” properties of drugs  Mood & movement  Attention & memory 2. Serotonin  Mood & sleep  Desire & impulse  Stimulants & Hallucinogens 3. Norepinephrine  Mood & movement  Memory & sensory processing  Stimulants
  5. 5. Chemical Pathways: Neurotransmitters 4. GABA  Sedation, drowsiness and relaxation  Depressants 5. Endorphins  Pain relief & sedation  Rate of bodily functions  Opioids 6. Glutamate  Learning, cognition & memory  Hallucinogens & alcohol 7. Acetylcholine  Involved in diverse processes: memory, attention & mood  Nicotine
  6. 6. Impact on Neurotransmission Psychoactive substances can impact neurotransmitters in both the intoxication and withdrawal process Many ways psychoactive drugs can impact neurotransmission - 3 common ways:  Increase neurotransmitter activity  Agonist  Reduce neurotransmitter activity  Antagonist  Blocking reuptake of neurotransmitter  Reuptake inhibitors
  7. 7. Chemical Theories of Behavior Variations in behavior explained through changes in brain chemistry  Historical and cultural perspectives  Monoamine theory of mood  Issue of experimental support Brain imaging techniques  Types  Reactions

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