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Horst's Keynote Stem Cell Science

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Horst's Keynote Stem Cell Science

  1. 1. P L A N T S T E M C E L L S C I E N C ER E V I T A L I Z E R E J U V E N A T E R E S T O R E EDELWEISS CONEFLOWER PENNYWORT (Leontopodium Alpinum) (Echinacea Angustifolia) (Centella Asiatica) A n Eco-brea kt h rou gh in A nt i-A ging Skin Scie nc e: Ble n d i n g Pla nt St e m C e lls for M a x i m u m Effic a c y S E P T E M B E R 2 011
  2. 2. P L A N T S T E M C E L L S C I E N C EWHAT IS PLANTSTEM CELL SCIENCE?An Eco-breakthrough in Anti-Aging Skin Science featuring:• A bioadvanced technology in reproducing the highest, most concentrated and pure plant ingredients.• Obtained with a truly eco-sustainable approach.• Delivered to the consumer, products that reduce fine lines and wrinkles, balance skin tone, and smooth, firm and softens skin.
  3. 3. P L A N T S T E M C E L L S C I E N C EHOW IT WORKS:PROTECT AND REPAIRIn nature plants are attacked byenvironmental stress such as UVA/UVBradiation, heavy metals, insects, viruses,micro-organisms and others.To protect themselves plants usephenylpropanoids (protecting agents/antioxidants) which are mainly concentratedin stem cells.
  4. 4. P L A N T S T E M C E L L S C I E N C ERARE AND PRECIOUSSuper powered and relatively few in number these stem cells are concentrated in the mostvulnerable part of the plant helping to fight against free radical damage while also providingUV protection and anti-bacterial properties. Luminescent dots represent these highly active cells.
  5. 5. P L A N T S T E M C E L L S C I E N C EREVOLUTIONARY CULTIVATION PROCESS:HIGHEST POTENCY WITH LESS RESOURCESIt may be a leaf, a flower or a seed—only a small amount of plant tissue is required to findspecific active substances. Plant tissue Sampling of sterilized Callus induction in solid tissues Callogenesis culture Callogenesis increases New cell line Selection Scaling Up
  6. 6. P L A N T S T E M C E L L S C I E N C EQUALITY AND SAFETYThe quality and safety of plant active substances have always been a problemSAFETYThe presence of pollutants and pesticides, heavy metals and aflatoxins is detected in manyplant actives and extractsAVAILABILITYMany problems due to difficult accessibility of plants, compromise the availability ofNatural Active SubstancesPURITY & STANDARDIZATIONThe variability in the concentration of active substances is a limit to the reproducibility ofthe biological effect 90% of users of herbal/natural health products declare that safety and efficacy influence the choice of the product**Blumenthal M: Natural Marketing Institute measures consumer use of herbal products. HerbalGram 2000;50:70.
  7. 7. P L A N T S T E M C E L L S C I E N C EBENEFITS• The highest, most active molecules can be isolated in a larger quantity with fewer plants to deliver more efficacious highly potent ingredients—up to 1,000 times higher in potency.• Now through cutting edge technology we can obtain cells from even the most rare plant species without harm and ensure availability for generations to come as no plant is destroyed with this method.• 100% free from herbicides, pesticides and supports sustainability as soil can be used to cultivate food.• Farming is not required, so no significant contribution to green house gases is produced from this process.• Drastic reduction of water and solvent use—alcohol, glycol and preservatives are not used in the extraction process.• No genetic modification.
  8. 8. P L A N T S T E M C E L L S C I E N C ETHE LINK BETWEENPLANT & SKIN:HOW IT HELPS PREVENT THE SIGNS OF AGINGThe meristematic cells are concentrated and rich in phenylpropanoids.Phenylpropanoids are active substances that possess significant antioxidant, free radicalscavenging, and UV protecting and anti-bacterial properties.As we know skin inflammation and oxidative stress induced by environmental factorsor chemical irritants is a major cause of collagen damage resulting in loss of skin tone,elasticity and the appearance of wrinkles (the signs of aging).While intrinsic aging cannot be halted environmental factors can be controlled andphenylpropanoids are ideal protecting agents since the external damaging factors arethe same for both plants and skin.
  9. 9. P L A N T S T E M C E L L S C I E N C ESUSTAINABILITY:AN UNAVOIDABLE CHOICEThe extraction of echinacoside requires a 3-year soil cultivation of Echincacea beforecollecting roots.Average inputs for the production of 1kg Echinacea plant stem cells SOLVENTS (Kg) BIOTECH Method TRADITIONAL 500 Method WATER (t) 1379 AREA (m2) 1149 0 200 400 600 800 1000 1200 1400
  10. 10. P L A N T S T E M C E L L S C I E N C ESUSTAINABILITY:AN UNAVOIDABLE CHOICEThe extraction of echinacoside requires a 3-year soil cultivation of Echincacea beforecollecting roots.Average inputs for the production of 1kg Echinacea plant stem cells SOLVENTS (Kg) HTN IS AN ECO-SUSTAINABLE, GREEN 100 BIOTECH Method BIOTECH PROCESS: 500 TRADITIONAL Method • Preserving biodiversity WATER (t) • Negligible soil occupancy (soil can be 1 cultivated for food) 1379 • Drastic reduction in water and solvent use AREA (m2) 3* • No use of pesticides 1149 High Tech Nature Source: VV.AA., Agronomical trials on Echinacea angustifolia, E. pallida, E. purpurea, ISAFA 2002/1; G. Nebbia, The cost in water of goods and services, 0 200 400 600 800 1000 1200 1400 University of Rome, 18-19th January 2001, International Water Culture Center. *323 sq. ft. vs. 1/4 acre of land (10,890 sq. ft.)
  11. 11. P L A N T S T E M C E L L S C I E N C EWE CAN SAVE WATEROne customer using 6 units of 50ml cream can save 1 ton of water per year = 170 LITERS OF WATER
  12. 12. P L A N T S T E M C E L L S C I E N C EPROPRIETARY BLENDWe have formulated our signature proprietary stem cell blend at the highest potency,delivering maximum efficacy to revitalize skin cells, rejuvenate aging skin, restoreelasticity and brighten skin. Our blend consists of: ACTIVE PLANT STEM CELLS ACTIVITY* • Reduces wrinkles and helps maintain skin firmness EDELWEISS • Rejuvenates damaged cells {Leontopodium Alpinum} • Reduces the signs of photoaging • Stimulates collagen synthesis (cell renewal) CONEFLOWER • Increases hydration and elasticity {Echinacea Angustifolia} • Revitalizes dull and tired skin • Evens skin tone PENNY WORT • Improves elasticity {Centella Asiatica} • Provides firming benefits*BASED ON LAB AND CLINCAL STUDIES. Results improve with continued use.
  13. 13. P L A N T S T E M C E L L S C I E N C E R E V I T A L I Z E R E J U V E N A T E R E S T O R EINTERNAL EXTERNAL(PHASE 2—2011) (PHASE 1— On counter September 2011)
  14. 14. PHASE 1P L A N T S T E M C E L L S C I E N C ERENEWAL COMPLEXEXTERNALProvides intensive treatment benefits to reduce fine lines and wrinklesdiffuse age spots and soften stretch marks and scars, reduce rednessand other skin discolorations. Firms, lifts, smooths and softens whileincreasing collagen synthesis.ALL OVER TREATMENT TARGET TREATMENTFor treatment of larger skin surface areas. For intense spot treatment.SIZE: 4 Treatment Vials (1.62 fl oz/48ml) SIZE: 1 Treatment Vial (0.4 fl oz/12ml)Suggested Retail: $130 Suggested Retail: $55USAGE: USAGE:• Apply to face, neck, décolleté and breasts as • Apply to wrinkles surrounding mouth, treatment and preventative. upper lip, delicate eye area and forehead.• A one-month supply in four, 12ml vials with • Use as intense treatment on age spots. hygienic applicators. • Apply to stretch marks, scars and other skin• Apply twice daily, in the morning and imperfections. before bed, prior to moisturizing.• Each bottle designed to last approximately 7-10 days.
  15. 15. PHASE 1P L A N T S T E M C E L L S C I E N C EALL OVER TREATMENTFor treatment of larger skin surface areas.SIZE: 4 Treatment Vials (1.62 fl oz/48ml)Suggested Retail: $130USAGE:• Apply to face, neck, décolleté and breasts as treatment and preventative.• A one-month supply in four, 12ml vials with hygienic applicators.• Apply twice daily, in the morning and before bed, prior to moisturizing.• Each bottle designed to last approximately 7-10 days.
  16. 16. PHASE 1P L A N T S T E M C E L L S C I E N C ETARGET TREATMENTFor intense spot treatment.SIZE: 1 Treatment Vial (0.4 fl oz/12ml)Suggested Retail: $55USAGE:• Apply to wrinkles surrounding mouth, upper lip, delicate eye area and forehead.• Use as intense treatment on age spots.• Apply to stretch marks, scars and other skin imperfections.
  17. 17. PHASE 2P L A N T S T E M C E L L S C I E N C ENUTRACEUTICALFIBER SACHETSINTERNALSIZE: 30 SachetsINGREDIENTS: Coneflower, Baobab FiberKEY CLAIMS• Daily consumption helps decrease oxidative stress damage and limit inflammation.• Fiber helps cleanse and purify the body, thus allowing maximum absorption of the plant stem cells.• Nourishes skin.USAGE TIPS:• Add to water, juice or any other liquid and drink daily.• Add to room temperature or cooler liquids only for maximum efficacy.
  18. 18. • Cosmetic products formulated to add turgidness to lips • Cosmetic products formulated to fight enlarged pores PL ANT STEM CELL SCIENCE INGREDIENT • Cosmetic products formulated to reduce the cellulite Subjects undergoing the trial: Nr 30-60 subjects, age: 18 – 60, sex: M/F. possibly represen CLINICAL STUDY OF EDELWEISS Criteria of volunteers selection: Good health condition No participation in analogous trials in the two previous mo PROTOCOL Negative anamnesis for allergenic skin reactions Absence of skin pathologies Absence of topic pharmacological treatment in progress − Every volunteer is given a form to fill in and subscribe, in o to the above mentioned conditions. Every volunteer is given a form to fill in and subscribe in order to e• 20 subjects ages 35-65 that no condition of test exclusion is present. Experimental procedures: one of the following experimental proce• Study featured both qualitative and instrumental methodology Before, during and after the treatment Positive control or market benchmark of proven efficacy Comparison among differently formulated products• Applied product with 1% Edelweiss twice per day Instrumentation The measurement is carried out by DERMATOP BLUE (EOTECH, F• Skin was measured at onset of test, at 22 days and at 40 days DERMATOP BLUE is a skin scanner to perform tests for the evaluat results obtained evaluating the volunteers at time 0 and after the tre• Used state-of-the-art Dermatop Blue Scanner The perfo to re eye b A sen the z that of r (pore cellul perfo finally photo
  19. 19. PL ANT STEM CELL SCIENCE INGREDIENT CLINICAL STUDY OF EDELWEISS EYE CONTOUR• Used Blue Light Technology• Two of the subjects most representational of the effects SUBJECT Before the Treatment After 22 days of application After 40 days of application 15% IMPROVEMENT 18.3% IMPROVEMENT
  20. 20. PL ANT STEM CELL SCIENCE INGREDIENT CLINICAL STUDY OF EDELWEISS  WRINKLE DEPRESSION        • Area 20mm x 20mm                                • Pink indicates the deepest area of the wrinkle                         Before the Treatment After 22 days of application After 40 days of application      
  21. 21. P L A N T S T E M C E L L S C I E N C E
  22. 22. P L A N T S T E M C E L L S C I E N C EIN SUMMARY1. Highest blended potency2. Maximum efficacy3. Greenest Quality
  23. 23. P L A N T S T E M C E L L S C I E N C ER E V I T A L I Z E R E J U V E N A T E R E S T O R E EDELWEISS CONEFLOWER PENNYWORT (Leontopodium Alpinum) (Echinacea Angustifolia) (Centella Asiatica) A n Eco-brea kt h rou gh in A nt i-A ging Skin Scie nc e: Ble n d i n g Pla nt St e m C e lls for M a x i m u m Effic a c y S E P T E M B E R 2 011

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