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Integrating Noninvasive Blood Pressure Monitoring with Human Physiology Measurements

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Experts discuss the fundamentals of real-time, beat-to-beat noninvasive blood pressure (NIBP) monitoring and present new research capabilities enabled through the integration of NIBP technology and physiological recording systems.

In this webinar sponsored by BIOPAC Systems and CNSystems, Frazer Findlay and Walter Habenbacher discuss study design and demonstrate correct equipment set up and operation when recording NIBP with additional physiological signals. Specifically, Mr. Habenbacher explains the application of the NIBP100D-HD to measure noninvasive continuous blood pressure. He demonstrates setup & measurement and shows how scientific findings can benefit your research with advanced hemodynamic monitoring.
Following, Mr. Findlay demonstrates how to interface the NIBP100D Continuous Noninvasive Blood Pressure Monitor with the BIOPAC MP160 Data Acquisition and Analysis System and simultaneously recorded measurements of NIBP, ECG and respiration. In addition, Mr. Findlay discusses important data analysis processes such as computing cardiac output and stroke volume, and demonstrates how scientists can use the “Focus Areas” feature in AcqKnowledge Software to simplify their data review.

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Integrating Noninvasive Blood Pressure Monitoring with Human Physiology Measurements

  1. 1. Integrating Noninvasive Blood Pressure Monitoring with Human Physiology Measurements Experts discuss the fundamentals of real-time, beat-to-beat noninvasive blood pressure (NIBP) monitoring and present new research capabilities enabled through the integration of NIBP technology and physiological recording systems.
  2. 2. InsideScientific is an online educational environment designed for life science researchers. Our goal is to aid in the sharing and distribution of scientific information regarding innovative technologies, protocols, research tools and laboratory services. JOIN FOR FREE AT WWW.INSIDESCIENTIFIC.COM
  3. 3. Walter Habenbacher Head of Sales & Marketing, CNSystems Medizintechnik AG NIBP100D-HD Hemodynamic Monitoring @ Your Fingertips © CNSystems Medizintechnik AG. 2016 www.cnsystems.com
  4. 4. www.cnsystems.com 4 MOVING FROM SNAPSHOTS… …TO CONTINUOUS INFORMATION NBP CNAP®
  5. 5. www.cnsystems.com 5 Hemodynamic monitoring @ your fingertips NIBP100D-HD – CONTINUOUS & NONINVASIVE * CE approved / FDA pending. Blood Pressure Cardiac Output & Stroke Volume* Systemic Vascular Resistance* Pulse Rate [click to learn more]
  6. 6. www.cnsystems.com 6 SETUP & CALIBRATION click to watch the videos [advance to 06:08]
  7. 7. www.cnsystems.com 7 CNAP® TECHNOLOGY – HOW IT WORKS IR light picks up blood volume and flow1 2 In- and deflating pressure cuff follows pulsation and keeps blood flow constant 1 3 High accuracy thru calibration with NBP 2 2 IR light 1 Sys Dia Mean 3 1 Jan Penaz, Brno, Czech Republic 1973 2 Fortin J et al.: Continuous noninvasive BP monitoring using concentrically interlocking control loops. Comput in Biol Med 36 (2006)
  8. 8. www.cnsystems.com 8 CNAP® TECHNOLOGY – HOW IT WORKS click to watch the video [advance to 10:05]
  9. 9. www.cnsystems.com 9 SETTING UP MEASUREMENTS IS EASY  Measurement settings measurement 30min setup 5min buffer 5min  Total time: ≈ 40min  Set CNAP Cal Interval to 40min (switch between fingers)  Set NBP Interval to 40min (calibration to upper arm)
  10. 10. www.cnsystems.com 10 PROVEN TECHNOLOGY OVER DECADES http://www.cnsystems.com/literature Task Force® Monitor NIBP100D Over 500 peer reviewed publications reflect the trust in the accuracy and utility in research & clinical settings
  11. 11. www.cnsystems.com 11 PERFORMANCE DURING VALSALVA Initial BP rise Impeded venous return (fall in BP) Compensation (pulse rate & vasoconstriction) Pressure release Overshoot (return of CO) 1 2a 3 4 2b 40 50 60 70 80 90 100 0 10 20 30 40 50 60 70 80 BloodPressure[mmHg] VALSALVA 1 2a 2b 3 4
  12. 12. www.cnsystems.com 12 PERFORMANCE DURING VALSALVA click to watch the video [advance to 14:36]
  13. 13. www.cnsystems.com 13 THE ROLE OF CARDIAC OUPUT & VASCULAR RESISTANCE Blood pressure Resistant Blood flow MABP = HR x SV x SVR The Ohm´s law applied to physiology
  14. 14. www.cnsystems.com 14 1 Kirby, L. D., & Wright, R. A. (2003). Cardiovascular correlates of challenge and threat appraisals: A critical examination of the Biopsychosocial Analysis. Personality and Social Psychology Bulletin,7, 216-233. 2 Tomaka, J., Blascovich, J., Kelsey, R. M., & Leitten, C. L. (1993). Subjective, physiological, and behavioral effects of threat and challenge appraisal. Journal of Personality and Social Psychology,65, 248-260. 3 Lackner, H. K., Weiss, E. M., Schulter, G., Hinghofer-Szalkay, H., Samson, A. C., & Papousek, I. (2013). I got it! Transient Cardiovascular Response to the Perception of Humor. BiologicalPsychology, 93, 33–40. BLOOD PRESSURE, CARDIAC OUTPUT AND VASCULAR RESISTANCE ARE IMPORTANT CV CORRELATES OF CHALLENGE & THREAT
  15. 15. www.cnsystems.com 15 HEMODYNAMIC MONITORING @ YOUR FINGERTIPS: CONTINUOUS & NONINVASIVE Calibrated blood pressure & hemodynamics Up & running in 1.5 minutes Quick set up of measurement Reliable short and longterm monitoring Easy integration (MP150 / 160)
  16. 16. Frazer Findlay CEO, BIOPAC Systems, Inc. Integrating NIBP with Human Physiology Measurements BIOPAC—Inspiring people and enabling discovery about life © BIOPAC Systems, Inc. 2016 www.biopac.com
  17. 17. BIOPAC—Inspiring people and enabling discovery about life © BIOPAC Systems, Inc. 2016 www.biopac.com 17 Over 97% of top universities run BIOPAC Systems THE WORLD DISCOVERS WITH BIOPAC Solutions for life science research and education
  18. 18. BIOPAC—Inspiring people and enabling discovery about life © BIOPAC Systems, Inc. 2016 www.biopac.com 18 Combining Noninvasive Blood Pressure with other Physiological Signals BioNomadix Wireless Physiological Data Mobita System 32-Channel EEG / Biopotentials B-Alert System 9-Channels of EEG and Cognitive States Metrics MP36R System 4-Universal Channels MP160 System 16-Channels of Tethered or Wireless Signals
  19. 19. BIOPAC—Inspiring people and enabling discovery about life © BIOPAC Systems, Inc. 2016 www.biopac.com 19 Stimulus Presentation with Triggers for Synchronization SuperLab® - E-Prime® Presentation® Virtual Reality BIOPAC VR Solutions offer real-time feedback loops and event marking
  20. 20. BIOPAC—Inspiring people and enabling discovery about life © BIOPAC Systems, Inc. 2016 www.biopac.com 20 Stationary Eye Tracking with Visual Stimulation Unrestrained Mobile Eye Tracking
  21. 21. BIOPAC—Inspiring people and enabling discovery about life © BIOPAC Systems, Inc. 2016 www.biopac.com 21
  22. 22. BIOPAC—Inspiring people and enabling discovery about life © BIOPAC Systems, Inc. 2016 www.biopac.com 22 Hardware Communication NIBP100D Continuous Noninvasive Blood Pressure System DA100C with TCI105 MP160 System 16-Channel Data Acquisition System
  23. 23. BIOPAC—Inspiring people and enabling discovery about life © BIOPAC Systems, Inc. 2016 www.biopac.com 23 Hardware Communication CBLNIBP100D-HD HLT100C and 4 x INISO Isolation Adapters NIBP100D-HD Continuous Noninvasive Blood Pressure System with Hemodynamics HemodynamicMeasurement Cardiac Output (CO), Stroke Volume (SV), Pulse Pressure Variation (PPV),Stroke Volume Variation (SVV),Systemic Vascular Resistance(SVR) MP160 System 16-Channel Data Acquisition System
  24. 24. BIOPAC—Inspiring people and enabling discovery about life © BIOPAC Systems, Inc. 2016 www.biopac.com 24 Hardware Communication with Visual Stimulus Stimulus is delivered to subject at a stationary monitor or by VR... SuperLab E-Prime Vizard Presentation Front FrontBack STP100C
  25. 25. BIOPAC—Inspiring people and enabling discovery about life © BIOPAC Systems, Inc. 2016 www.biopac.com 25 Hardware Communication with Visual Stimulus Stimulus is delivered to subject at a stationary monitor or by VR... Front FrontBack STP100C
  26. 26. BIOPAC—Inspiring people and enabling discovery about life © BIOPAC Systems, Inc. 2016 www.biopac.com 26 Hardware Communication with Visual Stimulus Stimulus is delivered to subject at a stationary monitor or by VR... Triggers sent to the MP160 System Front FrontBack STP100C
  27. 27. BIOPAC—Inspiring people and enabling discovery about life © BIOPAC Systems, Inc. 2016 www.biopac.com 27 AcqKnowledge Automated Analysis Software • Arterial Blood Pressure Analysis • Estimate Cardiac Output from Arterial Blood Pressure • Baroreflex Sequence Analysis • Baroreflex Slope Analysis
  28. 28. Demonstration of AcqKnowledge Software [click to watch the demonstration – advance to 31:11]
  29. 29. BIOPAC—Inspiring people and enabling discovery about life © BIOPAC Systems, Inc. 2016 www.biopac.com 29 • Combine Noninvasive Blood Pressure with a wide variety of signals • Interface with stimulus presentation systems such as E-Prime, SuperLab, Presentation and BIOPAC Virtual Reality systems • Monitor subject eye position, gaze path and facial expressions • Maintain synchronization across devices Summary
  30. 30. Walter Habenbacher office@cnsystems.com Frazer Findlay info@biopac.com For additional information on the products and applications presented during this webinar please visit www.cnsystems.com and www.biopac.com Thank You

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