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…Improving Health Through Technology




         UBS Global Life Sciences
              Conference
                 September 20, 2012
Safe Harbor Statement
“Safe Harbor” Statement under the Private Securities Litigation Reform Act of 1995:

To the extent any statements made in this presentation contain information that is not historical, these statements are
forward-looking in nature and express the beliefs and expectations of management. Such statements are based on current
expectations and involve a number of known and unknown risks and uncertainties that could cause the Company’s future
results, performance or achievements to differ significantly from the results, performance or achievements expressed or
implied by such forward-looking statements. Such risks and uncertainties include, but are not limited to, the effect of current
economic conditions on the Company’s industry, business, financial position and results of operations, fluctuations in the
Company’s revenues and operating income, the Company’s ability to successfully develop and commercialize pharmaceutical
products, reductions or loss of business with any significant customer, the impact of consolidation of the Company’s customer
base, the impact of competition, the Company’s ability to sustain profitability and positive cash flows, any delays or
unanticipated expenses in connection with the operation of the Company’s Taiwan facility, the effect of foreign economic,
political, legal and other risks on the Company’s operations abroad, the uncertainty of patent litigation, increased government
scrutiny on the Company’s agreements with brand pharmaceutical companies, consumer acceptance and demand for new
pharmaceutical products, the difficulty of predicting Food and Drug Administration filings and approvals, the Company’s
inexperience in conducting clinical trials and submitting new drug applications, the Company’s ability to successfully conduct
clinical trials, the Company’s reliance on third parties to conduct clinical trials and testing, the availability of raw materials and
impact of interruptions in the Company’s supply chain, the use of controlled substances in the Company’s products,
disruptions or failures in the Company’s information technology systems and network infrastructure, the Company’s reliance
on alliance and collaboration agreements, the Company’s dependence on certain employees, the Company’s ability to comply
with legal and regulatory requirements governing the healthcare industry, the regulatory environment, the Company’s ability to
protect the Company’s intellectual property, exposure to product liability claims, changes in tax regulations, the Company’s
ability to manage the Company’s growth, including through potential acquisitions, the restrictions imposed by the Company’s
credit facility, uncertainties involved in the preparation of the Company’s financial statements, the Company’s ability to
maintain an effective system of internal control over financial reporting, any manufacturing difficulties or delays, the effect of
terrorist attacks on the Company’s business, the location of the Company’s manufacturing and research and development
facilities near earthquake fault lines and other risks described in the Company’s periodic reports filed with the Securities and
Exchange Commission. Forward-looking statements speak only as to the date on which they are made, and Impax
undertakes no obligation to update publicly or revise any forward-looking statement, regardless of whether new information
becomes available, future developments occur or otherwise.

Note: All product sales data included herein are derived from data published by Wolters Kluwer Health for the 12 months
ended July 2012.
Trademarks referenced herein are the property of their respective owners.
©2012 Impax Laboratories, Inc. All Rights Reserved.
2
Impax’s Dual Strategic Focus




     Unique targeted ANDAs             Create valued CNS products
     First-to-File, First-to-Market    Develop strong IP positions
     Sustainability through            IPX066 (RYTARYTM) NDA
     technically challenging,          filed 4Q11 as 505(b)(2) filing
     difficult to formulate products
     Partnership for in-licensing      IPX159 in Phase IIb as
     or co-development of              505(b)(1) filing
     alternative dosage forms
                                       Licensed exclusive U.S.
     46 apps pending at FDA            commercialization rights to
     52 under development              Zomig®


3     Note: Data as of July 31, 2012
Healthy Balance Sheet Supports Ongoing M&A
    Significant cash and no debt for investments in growth initiatives




                                       Strategically
                         Financially      Right
                         Attractive


                                 Manageable
                                  Execution
                                    Risk




              Generic & Brand M&A Candidates
4
…A Leader in Generic Medicines
Generic Growth Initiatives




6
98 Products Pending or Under Development

                                                         Future Targeted Opportunities
                                                      $36 Billion Current U.S. Brand/Generic Sales


                       Present
                                                                                           46
                                                                                    Pending at FDA
                         41                                                             ($20 Billion)

                     Currently
                     Marketed
                      ANDAs                                                               52
                                                                               Under Development
                                                                                        ($16 Billion)

      Note: All product sales data included herein are derived from data published by
7     Wolters Kluwer Health for the 12 months ended July 2012.
Growing Alternative Dosage Form Partnership Portfolio
    Currently ADF portfolio of 24 products:
       – 9 approved
       – 5 pending at the FDA                             Brand and Generic sales >$2.5B…a number of them
       – 10 under development                             still First-to-File or First-to-Market opportunities

                                    •   Multiple development, supply and distribution agreements
                                    •   9 approved products
                                    •   2 topical products pending at FDA
                                    •   7 ADF products under development

                                    • Supply and commercialization agreement
                                    • 1 softgel capsule product pending at FDA
                                    • 1 softgel capsule product under development

                                    • Development and commercialization agreement
                                    • 2 nasal spray products pending at FDA

                                    • Development and supply agreement
                                    • 2 topical products under development

       Note: All product sales data included herein are derived from data published by
8
       Wolters Kluwer Health for the 12 months ended July 2012.
…Advancing CNS Treatment
Brand Growth Initiatives




                           Internal R&D
                             Programs



                        Approval and launch
                         of RytaryTM in U.S.
                          Commercialize
                          Zomig® in U.S.




10
RYTARY™ (IPX066): ER Carbidopa and Levodopa

     • Extended release capsule formulation of CD-LD intended to
       maintain consistent plasma concentration of levodopa for a longer
       duration verses competitive levodopa products

     • Indicated for the symptomatic treatment of adult patients with
       idiopathic Parkinson’s disease

     • Three phase III studies completed in naive and advanced patients,
       with primary endpoint measuring reduction of “off time”




11
RYTARYTM (IPX066): Next Steps in 2012

      Formulation Patent   Dec.   Feb.   Oct. 21,
                                                      Throughout 2012
         Information       2011   2012    2012

              Development Milestones
                                                    Pre-launch
 1st patent granted                                 preparation and
      Aug. 2006                  FDA               launch planning
      Expires May 2022    NDA acceptance PDUFA
                           filed of NDA    Date       Building
 2nd patent submission            Filing               marketing and
      Dec. 2008                                       sales team
      Expires Dec. 2028                              Conducting
                                                       commercial pre-
                                                       launch activities




12
Clinical Stage Pipeline - IPX159
                                        IPX159 – Restless Legs Syndrome (RLS)
      Product                     •    Ex-US compound (for a different indication), NCE US
      Overview                    •    Inhibits uptake of neurotransmitters



       IPX159                  Phase IIb study underway
     Development
      Overview                 US registration path 505(b)(1) – 5 year regulatory exclusivity


                                                         Significant Commercial Opportunity
     RLS Market                                                                  25 million in          ~$800 million
     Opportunity                   Large                   Limited                  U.S.
                                                                                                            total          Good
                                opportunity in             pipeline              experience
                                                                                                         prescription   commercial fit
                                  the U.S.               competition                RLS
                                                                                  symptoms               market size



       Note: Patient information derived from Datamonitor. All product sales data included herein are derived
       from data published by Wolters Kluwer Health and IMS NDTI June 2010.
       “Data on file, Impax Laboratories”
13
IPX159: Development Status

 Preclinical & POC   Phase I Phase IIa            Phase IIb – Initiated December 2011


                                              • Primary endpoint: International Restless
        Completed

                      Completed
                                  Completed
                                                Legs Syndrome Study Group (IRLSSG)
                                                Rating Scale
                                              • Safety and efficacy study
                                              • North America, randomized, double-
                                                blind, placebo-controlled trial
                                              • Approximately 120 subjects
                                              • 11 week trial
                                              • Results expected first-half 2013




14
Taiwan Manufacturing Expansion

     • July 2012 FDA preapproval inspection for RYTARYTM and
       undisclosed generic drug with no Form 483 observations
     • Primary manufacturing site for RYTARYTM
     • Two year expansion project to be completed mid 2013
     • Expanded footprint provides space for installation of additional
       equipment as needed
        – Capable of supporting annual production of 2B doses




15
Strong Platform for Long Term Growth



                  Generic                       Brand
              Unique Targeted             Offering Long-Term
             High Value ANDAs               Growth Drivers




                                Drug Delivery
                                  Expertise




                            Core Competency
                           Product         Formulation
                         Development       Technology

16

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UBS Global Life Sciences Conference

  • 1. …Improving Health Through Technology UBS Global Life Sciences Conference September 20, 2012
  • 2. Safe Harbor Statement “Safe Harbor” Statement under the Private Securities Litigation Reform Act of 1995: To the extent any statements made in this presentation contain information that is not historical, these statements are forward-looking in nature and express the beliefs and expectations of management. Such statements are based on current expectations and involve a number of known and unknown risks and uncertainties that could cause the Company’s future results, performance or achievements to differ significantly from the results, performance or achievements expressed or implied by such forward-looking statements. Such risks and uncertainties include, but are not limited to, the effect of current economic conditions on the Company’s industry, business, financial position and results of operations, fluctuations in the Company’s revenues and operating income, the Company’s ability to successfully develop and commercialize pharmaceutical products, reductions or loss of business with any significant customer, the impact of consolidation of the Company’s customer base, the impact of competition, the Company’s ability to sustain profitability and positive cash flows, any delays or unanticipated expenses in connection with the operation of the Company’s Taiwan facility, the effect of foreign economic, political, legal and other risks on the Company’s operations abroad, the uncertainty of patent litigation, increased government scrutiny on the Company’s agreements with brand pharmaceutical companies, consumer acceptance and demand for new pharmaceutical products, the difficulty of predicting Food and Drug Administration filings and approvals, the Company’s inexperience in conducting clinical trials and submitting new drug applications, the Company’s ability to successfully conduct clinical trials, the Company’s reliance on third parties to conduct clinical trials and testing, the availability of raw materials and impact of interruptions in the Company’s supply chain, the use of controlled substances in the Company’s products, disruptions or failures in the Company’s information technology systems and network infrastructure, the Company’s reliance on alliance and collaboration agreements, the Company’s dependence on certain employees, the Company’s ability to comply with legal and regulatory requirements governing the healthcare industry, the regulatory environment, the Company’s ability to protect the Company’s intellectual property, exposure to product liability claims, changes in tax regulations, the Company’s ability to manage the Company’s growth, including through potential acquisitions, the restrictions imposed by the Company’s credit facility, uncertainties involved in the preparation of the Company’s financial statements, the Company’s ability to maintain an effective system of internal control over financial reporting, any manufacturing difficulties or delays, the effect of terrorist attacks on the Company’s business, the location of the Company’s manufacturing and research and development facilities near earthquake fault lines and other risks described in the Company’s periodic reports filed with the Securities and Exchange Commission. Forward-looking statements speak only as to the date on which they are made, and Impax undertakes no obligation to update publicly or revise any forward-looking statement, regardless of whether new information becomes available, future developments occur or otherwise. Note: All product sales data included herein are derived from data published by Wolters Kluwer Health for the 12 months ended July 2012. Trademarks referenced herein are the property of their respective owners. ©2012 Impax Laboratories, Inc. All Rights Reserved. 2
  • 3. Impax’s Dual Strategic Focus Unique targeted ANDAs Create valued CNS products First-to-File, First-to-Market Develop strong IP positions Sustainability through IPX066 (RYTARYTM) NDA technically challenging, filed 4Q11 as 505(b)(2) filing difficult to formulate products Partnership for in-licensing IPX159 in Phase IIb as or co-development of 505(b)(1) filing alternative dosage forms Licensed exclusive U.S. 46 apps pending at FDA commercialization rights to 52 under development Zomig® 3 Note: Data as of July 31, 2012
  • 4. Healthy Balance Sheet Supports Ongoing M&A Significant cash and no debt for investments in growth initiatives Strategically Financially Right Attractive Manageable Execution Risk Generic & Brand M&A Candidates 4
  • 5. …A Leader in Generic Medicines
  • 7. 98 Products Pending or Under Development Future Targeted Opportunities $36 Billion Current U.S. Brand/Generic Sales Present 46 Pending at FDA 41 ($20 Billion) Currently Marketed ANDAs 52 Under Development ($16 Billion) Note: All product sales data included herein are derived from data published by 7 Wolters Kluwer Health for the 12 months ended July 2012.
  • 8. Growing Alternative Dosage Form Partnership Portfolio Currently ADF portfolio of 24 products: – 9 approved – 5 pending at the FDA Brand and Generic sales >$2.5B…a number of them – 10 under development still First-to-File or First-to-Market opportunities • Multiple development, supply and distribution agreements • 9 approved products • 2 topical products pending at FDA • 7 ADF products under development • Supply and commercialization agreement • 1 softgel capsule product pending at FDA • 1 softgel capsule product under development • Development and commercialization agreement • 2 nasal spray products pending at FDA • Development and supply agreement • 2 topical products under development Note: All product sales data included herein are derived from data published by 8 Wolters Kluwer Health for the 12 months ended July 2012.
  • 10. Brand Growth Initiatives Internal R&D Programs Approval and launch of RytaryTM in U.S. Commercialize Zomig® in U.S. 10
  • 11. RYTARY™ (IPX066): ER Carbidopa and Levodopa • Extended release capsule formulation of CD-LD intended to maintain consistent plasma concentration of levodopa for a longer duration verses competitive levodopa products • Indicated for the symptomatic treatment of adult patients with idiopathic Parkinson’s disease • Three phase III studies completed in naive and advanced patients, with primary endpoint measuring reduction of “off time” 11
  • 12. RYTARYTM (IPX066): Next Steps in 2012 Formulation Patent Dec. Feb. Oct. 21, Throughout 2012 Information 2011 2012 2012 Development Milestones Pre-launch 1st patent granted preparation and  Aug. 2006 FDA launch planning  Expires May 2022 NDA acceptance PDUFA filed of NDA Date  Building 2nd patent submission Filing marketing and  Dec. 2008 sales team  Expires Dec. 2028  Conducting commercial pre- launch activities 12
  • 13. Clinical Stage Pipeline - IPX159 IPX159 – Restless Legs Syndrome (RLS) Product • Ex-US compound (for a different indication), NCE US Overview • Inhibits uptake of neurotransmitters IPX159 Phase IIb study underway Development Overview US registration path 505(b)(1) – 5 year regulatory exclusivity Significant Commercial Opportunity RLS Market 25 million in ~$800 million Opportunity Large Limited U.S. total Good opportunity in pipeline experience prescription commercial fit the U.S. competition RLS symptoms market size Note: Patient information derived from Datamonitor. All product sales data included herein are derived from data published by Wolters Kluwer Health and IMS NDTI June 2010. “Data on file, Impax Laboratories” 13
  • 14. IPX159: Development Status Preclinical & POC Phase I Phase IIa Phase IIb – Initiated December 2011 • Primary endpoint: International Restless Completed Completed Completed Legs Syndrome Study Group (IRLSSG) Rating Scale • Safety and efficacy study • North America, randomized, double- blind, placebo-controlled trial • Approximately 120 subjects • 11 week trial • Results expected first-half 2013 14
  • 15. Taiwan Manufacturing Expansion • July 2012 FDA preapproval inspection for RYTARYTM and undisclosed generic drug with no Form 483 observations • Primary manufacturing site for RYTARYTM • Two year expansion project to be completed mid 2013 • Expanded footprint provides space for installation of additional equipment as needed – Capable of supporting annual production of 2B doses 15
  • 16. Strong Platform for Long Term Growth Generic Brand Unique Targeted Offering Long-Term High Value ANDAs Growth Drivers Drug Delivery Expertise Core Competency Product Formulation Development Technology 16