Presented by Diallo Adama at the inception workshop of the project on epidemiology and control of peste des petits ruminants in West Africa, Ouagadougou, Burkina Faso, 25-27 June 2019.

1. Overview of PPR in West Africa
Diallo Adama, CIRAD
ECo-PPR - Epidemiology and Control of Peste des
Petits Ruminants Inception Workshop for West Africa
Ouagadougou, Burkina Faso, 25-27 June 2019

2. 1942-1972 1980-1982 1987
2007 2008 2009-2011
Evolution of PPR Distribution in the world (2011)
Importance of Peste de Petits Ruminants

3. Dr Adama Diallo: CIRAD, ISRA-LNERV, Dakar-Hann, Sénégal Adama.diallo@cirad.fr
World PPR GEOGRAPHICAL DISTRIBUTION

4. Morbillivirus Genus
4

5. 5
Molecular Epidemiology of PPR
N gene-based Tree

6. N gene-based Tree

7. N gene-based Tree

8. 8
Evolution in PPRV Lineage distribution
I
II
III
IV

9. 9
Evolution in PPRV Lineage distribution
I
II
III
IV

10. 10
Evolution in PPRV Lineage distribution
I
II
III
IV

11. PPRV Molecular Study in WA
• David Shamaki: 1998. More than 200 samples were
collected from different areas in Nigeria: lineage II

12. PPRV Molecular Study in WA
• David Shamaki: 1998. More than 200 samples were
collected from different areas in Nigeria: lineage II
• Woma (2013): A total of 140 clinical samples from 16
sheep and 63 goats with symptoms suggestive
of PPR were collected from different states of Nigeria
during a four-year period (2010-2013): lineage II and
lineage IV
• Salami (2010-2014). More than 100 samples from
Outbreaks attended in Senegal: lineage II
• K. Tounkara (2014-2017). 48/512 positifs collected in
Mali: Lineage I, II and IV.

13. 13
Monitoring of PPRV circulation
West Africa
CIV 2009
HQ131963 Senegal 2010
GHANA 2010
KJ124744 Nigeria 2012
BENIN 2010
KJ124742 Nigeria 2012
Benin 1969
DQ840160(75/1-Nigeria)
KJ124767 Nigeria 2011
DQ840163 Ghana 1976
DQ840167 Ghana Accra/78
DQ840164 Nigeria 76/1
Lineage II
HQ131960 Cameroon 1997
KJ124765 Nigeria 2011
Cameron 2010
KJ124739 Nigeria 2012
KJ124740 Nigeria 2012
DRC 2012
Lineage IV
DQ840165 Senegal 1968
DQ840199 CIV 1989
DQ840174 Senegal 1994
DQ840171(1989-Guinea-Bissau)
Lineage I

14. Monitoring of PPRV circulation
14
NG TA 2012 250A
NG TA 2012 253
NG YO 2013 2161
NG YO 2013 2162
NG KA 2010 2160
NG KA 2012 2159
NG AD 2012 2167
NG TA 2012 23
NG TA 2012 355
NG TA 2012 17LV
NG TA 2012 TR7
NG ON 2012 832LV
NG ON 2012 832KD
NG TA 2012 367
NG AN 2012 2152
NG CR 2012 1810
NG IM 2012 2150LG
NG IM 2012 2149LV
NG AN 2012 2154
NG CR 2012 1807
NG CR 2012 1811
NG AN 2012 2151LG
NG CR 2012 1808
NG CR 2012 1806
NG PL 2013 2171
NG PL 2013 2170
NG AD 2010 NJ13LN
NG AD 2010 NJ13LG
HQ131921 SD2008 SOBAKHARTOUMKH
HQ131917 SD2000 ALAZAZABNSUD00
HQ131960 CM1997 CAMEROON97
HQ131962 CF2004 CAR04
HQ131920 SD2000 SOBAKHARTOUMKH
HQ131929 SD2000 EDDAMARNSUD001
DQ840173 IL1993 ISRAELARABELLA
DQ840186 IR1998 IRAN983
DQ840198 TJ2004 TAJIKISTAN04
KC207868 PK2012 PAKISTANOKARAM
JN009673 PK2010 PAKFAISALABAD2
JN009674 PK2010 PAKMULTAN2010
KC207875 PK2012 PPRMM69SHEEP20
EU340363 CN2007 TIBET0702
KC207883 PK2012 PPRMM77CAMEL20
HQ131961 BD2009 BANGLADESH09
DQ840179 IN1994 SASSAYANA942
DQ840196 SA1999 SAUDI999
DQ840184 TR1996 TURKEY96
DQ840181 IL1995 ISREAL953
DQ840180 IN1994 THATAGULLAN941
DQ840176 IN1994 INDIA94
DQ840177 IN1995 CALCUTTA95
DQ840182 IL1995 TAMILNADU952
DQ840188 IL1998 ISRAEL982
DQ840195 SA1999 SAUDI997
HQ131931 SD2008 EDDAMARNSUD08
HQ131923 MA2008 MOROCCO081
HQ131927 MA2008 MOROCCO089
HQ131924 MA2008 MOROCCO082
DQ840185 IR1998 IRAN98
KC207867 PK2012 PAKISTANOKARAM
IV
NG OG 2011 31GYM
NG KW 2012 1111MSLN
NG KW 2012 LG
DQ840192 ML1999 MALI991
HQ131963 SD2010 SENEGAL10
JN602080 SL2009 SIERRALEONEKAB
NG AK 2013 2205
BJ1969 IAEA
NG AK 2013 2202
NG OY 2011 110GYM14
NG SO 2013 72
DQ837640 002005 VACRUSSIA05
DQ840163 NG1976 ACCRA76
DQ840161 NG1975 NIGERIA752
DQ840162 NG1975 NIGERIA753
NG OY 2011 127GYM31
DQ840160 NG1975 VACNIGERIA751
DQ840166 GH1978 GHANA78
II
DQ840165 SN1968 SENEGAL68
DQ840170 GN1988 GUINEA88
DQ840199 CI1989 CI89
DQ840172 BF1988 BURKINA88
DQ840171 GW1989 BISSAU89
DQ840174 SN1994 SENEGAL94
I
DQ840168 OM1983 IBIR83
DQ840169 AE1986 DORCAS86
HQ131918 SD1971 GEDARIFKSUD71
DQ840183 ET1996 ETHIOPIA96
DQ840175 ET1994 ETHIOPIA94
III
100
70
95
84
68
97
80
97
96
95
65
87
89
87
87
77
93
68
56
90
87
96
78
59
67
69
70
66
81
50
64
86
61
78
74
67
88
85
100
71
84
100
100
98
71
86
NIGERIA

15. Map of West Africa showing sampling location
according to their PPRV lineage II genetic cluster
Closely related strains (same genetic cluster = same color in map) found
in multiple West African countries
Rond= échantillons séquencés pendant l’étude de Kadidia
Carré = séquences disponibles sur GenBank.

16. Evolution PPRV lineages distribution: West Africa
16
SENEGAL 1969 - 1970 LINEAGE I
2010 LINEAGE II
NIGERIA 1975 - 1995 LINEAGE II
2008 LINEAGE IV
BENIN
1969 LINEAGE II
2011 LINEAGE II
Ghana
1976
2010
LINEAGE II
LINEAGE II

17. 17
Evolution in PPRV Lineage distribution
I
II
III
IV
Lineage II has evolved
further in Western Africa,
replacing Lineage I
Lineage IV has spread
further from North to South

18. PPRV Lineages Evolution in WA

19. PPRV LINEAGE DISTRIBUTION IN WA.
19

20. Livestock trade routes in West Africa

21. Livestock Mobility in WA
21

22. PPR-GCES

23. Approche par stades à l’échelon national
Les stades correspondent à une combinaison de niveaux décroissants de
risque épidémiologique et de niveaux croissants de prévention et de
contrôle.

24. OIE PPR – Statut indemne:
56 pays + 1 zône

25. Protection Against PPR: PART of the Fight for Poverty Alleviation
THANKS