BUILD-AMR: Mitigating agriculture-associated
antimicrobial resistance in poultry value chains in
Uganda
B. Wieland1, A.Moodley1, I. Mbatidde1,2, D. Ndoboli1,2, B-A Tenhagen3, U.Roesler4, R.
Erechu5, A. Litta-Mulondo6, S. Kakooza7, J. Waiswa7 and C. Kankya2
1International Livestock Research Institute; 2Makerere University; 3Federal Institute for Risk Assessment (Bfr); 4Freie Universität Berlin; 5National Animal Disease
Diagnostic and Epidemiology Centre; 6National Livestock Resources Research Institute; 7VSF Germany
Cross component collaboration
Build AMR and VPH
• Sharing of laboratory protocols
• Potential for additional
collaborations since bacteriologic
analyses will be conducted in the
same labs at NaLIRRI and NADEC
Major achievements
• Capacity needs assessment
completed by VSFG
• Stakeholder mapping completed by
VSFG
• Development of PhD concept notes
Major challenges
• COVID-19
• Procurement difficulties
• Delayed recruitment
Problem: Antimicrobial resistance is a global One Health challenge, top ten
human health threat by WHO (2019), disproportionate burden in low- and
middle-income countries
Challenge: Limited national data AMU and AMR in LMICs
→ difficult to evaluate livestock associated AMR risks and identifying risk
pathways contributing to AMR in humans in LMICs.
→ no baseline data to measure success of AMR mitigating interventions.
Approach:
→ cross-sectional studies to identify AMR risks
longitudinal study to investigate temporal dynamics and transmission pathways
→ risk assessment to evaluate risks
→ identify interventions to reduce AMU
Graphical representation of the AMR studies, outputs and outcomes
This document is licensed for use under the Creative Commons
Attribution 4.0 International Licence. June 2020
Activities completed since June
2019
• Recruitment of two PhD fellows
and a Research Assistant
• NaLiRRI’s new lab is functional with
new equipment to boost capacity
for analyses
• VSFG recruited a staff for AMR
component
Outputs since June 2019
• Capacity needs assessment
• Stakeholder mapping
• PhD concept notes
PhD Dickson Ndoboli PhD Irene Mbatidde Dreck Ayebare
S. Kakooza
E.coli on a plate Antibiotic suscep. test
Funded by
ILRI thanks all donors and organizations which globally support its work
through their contributions to the CGIAR Trust Fund.
Risk assessment for
AMR in people
Modes of transmission of
AMR between sources
→Transmission modelling
Value of
training/interventions as a
risk mitigation measure
Study 1: Cross-sectiona study in 2 districts
(n=360 farms):
-AM use patterns
-AMR prevalence in poultry
Study 2: Longitudinal-transmission study (40
farms-dif.system)
-Patterns of AM use
-Monitoring production data
-Transmission pathway (molecular
epidemiology)
Training on AM use and other inteerventions to
mitigate AMR risks
-Monitor changes in KAP
-Monitor changes in AMR and production parameters
Study 2: Cross-sectional study
-Chicken meat and/or egges at
retail
-AMR and antibiotic residues
PolicyadvicetomitigateAMRrisksinpoultry
production
Develop
training
materials
AMUandAMR
capacityneeds
assessment,KAP
invaluechain
actors
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