Be the first to like this
Genetic variations at the leptin receptor gene locus have been linked to diseases accompanying obesity and/or
obesity-related diseases in different populations.
However, the results from Previous studies have reported conflicting results. The aim of this study was to investigate whether LEPR gene SNP Gln223Arg (rs1137101) is associated with obesity and type II diabetes in Saudi adult women.
Therefore, SNP rs1137101 in LEPR gene in a total of 425 women (150 obese diabetic, 130 obese non-diabetic, and 145 normal weight) was investigated using PCR and sequencing techniques.